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Empagliflozin + Linagliptin

Antidiabetic

Uses of Empagliflozin + Linagliptin

Empagliflozin + Linagliptin is a combination medicine used to manage type 2 diabetes in adults.

This combination is commonly used for:

• Type 2 diabetes mellitus: Helps lower and control blood glucose levels alongside diet and exercise.
• Blood sugar control through urinary glucose excretion: Helps the kidneys remove excess glucose from the body through urine.
• Combined blood sugar management: Used when increased insulin release and reduced glucose reabsorption by the kidneys are both needed to control blood sugar.

Side effects of Empagliflozin + Linagliptin

  • Nasopharyngitis
  • Urinary tract infection
  • Nausea
  • Vomiting
  • Constipation
  • Hypoglycemia
  • Cough
  • Genital Fungal Infection

How Empagliflozin + Linagliptin works

Empagliflozin + Linagliptin works through two different mechanisms that together help lower blood sugar levels in people with type 2 diabetes.

Empagliflozin belongs to a class of medicines called SGLT2 inhibitors. It blocks a protein in the kidneys responsible for reabsorbing glucose back into the blood, allowing excess glucose to be removed from the body through urine instead.

Linagliptin is a DPP-4 inhibitor. It blocks the enzyme that breaks down natural hormones called incretins, which help increase insulin release after meals and reduce the amount of glucose produced by the liver.

Together, Empagliflozin helps the body remove excess glucose through urine while Linagliptin improves the body's own insulin response after meals, providing complementary blood sugar control.

Certified content

Written By

docImg
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years

MBBS

Reviewed By

Dr. Mandeep Chadha
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Expert Advice

Dosage Forms Available

  • Empagliflozin + Linagliptin is available for use via the oral route (tablets).

Age and Dose Restrictions

  • This combination is meant for use in adults and children above 18 years of age.

Contraindications

  • This combination is contraindicated in patients with allergies to empagliflozin or linagliptin or in case of severe renal dysfunction and heart problems.

Other Medications To Avoid With This Medicine

  • The simultaneous use of medications, including beta-blockers (such as metoprolol, propranolol, and glaucoma eye drops like timolol), antidiabetic medications (such as glimepiride and insulin glargine), and antimanic agents (lithium), alongside [unspecified medication], is not recommended. Prior consultation with a doctor is essential before considering the use of any prescription or over-the-counter medications to ensure the safety of the combined treatment plan.

Overdose and Missed Dose

  • Taking more than the prescribed dose may worsen side effects such as low blood sugar, dehydration, or urinary tract infections. If you suspect an overdose, consult your doctor and follow the advice given.
  • If you miss a dose of Empagliflozin + Linagliptin, take it as soon as you remember. Avoid taking two doses together to make up for the missed one.

Use In Driving And Operating Machinery

  • This combination does not directly impact your ability to drive or operate machinery. However, they may lead to hypoglycemia, which can cause dizziness. Taking precautions to prevent low blood sugar while driving or handling machinery is essential.

Use in Pregnancy and Lactation

  • This combination is not recommended in pregnant and breastfeeding women.

Special Dietary & Lifestyle Recommendation

  • Making lifestyle changes, including dietary modifications and regular exercise, is essential when taking this combination to control blood sugar levels properly.
  • After initiating treatment with this combination, it's recommended to have your blood sugar levels reassessed after 15 days and, subsequently, at regular intervals every 3-6 months. This monitoring helps track the progress of the disease and allows for dose adjustments as needed.
  • If hypoglycemia occurs, it's essential to have a quick source of sugar readily available. Carry sugar candies, glucose tablets, or sugary foods and drinks without fat or protein, such as fruit juice, to promptly address low blood sugar episodes.

Frequently asked questions

This combination may start to work within a few hours, but it may take some time to see the full effects. It's important to continue taking it as your doctor prescribes, even if you start feeling better.

While taking this combination, be cautious to avoid hypoglycemia (low blood sugar). Avoid taking it if you are allergic to empagliflozin or linagliptin.

Do not stop taking this combination without consulting your doctor, even if you feel healthy. Abruptly discontinuing this medication can lead to uncontrolled blood sugar levels.

No, this combination typically does not affect fertility. However, if you have concerns about fertility and its impact on diabetes management, discuss them with your doctor.

Empagliflozin + Linagliptin is used to manage type 2 diabetes mellitus. It helps control blood sugar levels by increasing glucose excretion through urine and improving insulin regulation in the body.

Terms & Conditions


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Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346

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Name: Kishor Kumar

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