Divalrex 500 Tablet 10 is used to manage epilepsy and bipolar disorder. As an antiepileptic and mood-stabilizing agent (containing valproate), this medication works by increasing the levels of the inhibitory neurotransmitter GABA, which helps stabilize mood, prevent the abnormal electrical activity that causes seizures, and balance overall brain chemicals. The extended-release (ER) formulation provides sustained blood levels for reliable control. Additionally, the tablet is effective in preventing migraine headaches, reducing their frequency and intensity.
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Divalrex 500 Tablet 10
Strip of 10 Units
MRP ₹140
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CompositionAbout Divalrex 500 Tablet 10
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Uses of Divalrex 500 Tablet 10
Divalrex 500 Tablet 10 is used for managing epilepsy and mood disorders. It works by stabilizing brain activity, controlling seizures, and preventing bipolar episodes. This medicine restores the balance of neurotransmitters, supporting improved nerve function. Additionally, it is effective in preventing migraines, offering long-term support for patients requiring continuous management of these neurological conditions.
Directions for Use of Divalrex 500 Tablet 10
- Swallow the tablet whole with a glass of water.
- Do not crush, chew, or break the tablet.
- This medicine can be taken with or without food as prescribed by the doctor.
- Always follow your doctor's instructions about when and how to take this medicine.
Route of Administration
Divalrex 500 Tablet 10 is taken orally.
Side Effects of Divalrex 500 Tablet 10
Divalrex 500 Tablet 10 may cause diarrhoea, constipation, dizziness, drowsiness, hair loss, weight gain, tremors, and blurred vision.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Divalrex 500 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- Diarrhoea: You can try taking Divalrex 500 Tablet 10 with food to help manage these side effects.
- Dizziness: If you feel light-headed or sleepy after taking this medication, it might be helpful to take it at bedtime.
How Divalrex 500 Tablet 10 Works?
Divalrex 500 Tablet 10 contains divalproex (500 mg) and works in the body through the following mechanisms:
- Increases GABA levels: Divalproex increases levels of gamma-aminobutyric acid (GABA) in your brain. GABA is a neurotransmitter that helps regulate brain activity.
- Controls seizures: By enhancing GABA activity, divalproex effectively controls seizures by inhibiting excessive neuron firing.
- Stabilises mood: The enhancement of GABA activity also helps in mood stabilisation, thereby managing symptoms associated with bipolar disorder.
- Prevents migraines: Through its effect on GABA activity, divalproex reduces the frequency and intensity of migraine headaches.
Safety Measures & Warnings
Pregnancy
Divalrex 500 Tablet 10 is not advisable during pregnancy. If you're pregnant or planning to conceive, consult your doctor before taking this medicine.
Breastfeeding
Breastfeeding mothers should refrain from using Divalrex 500 Tablet 10. It's always wise to discuss with your doctor the potential risks and benefits.
Alcohol
While on this medicine, it's best to limit or avoid alcohol as it may intensify side effects such as dizziness and drowsiness.
Liver
As Divalrex 500 Tablet 10 can affect liver function, caution is advised if you have mild-to-moderate liver impairment. The medicine isn't recommended for severe liver diseases. Discuss your liver health with your doctor before starting this medicine.
Kidney
If you have a history of kidney problems, use Divalrex 500 Tablet 10 with caution. Consult your doctor before taking this medicine.
Use In Driving And Operating Machinery
Divalrex 500 Tablet 10 can cause dizziness and drowsiness, affecting your ability to operate machinery or drive. Do not engage in such activities until you know how the medicine affects you.
Allergy
Do not take Divalrex 500 Tablet 10 if you are allergic to divalproex or any of its inactive ingredients. Always check with your doctor if you've had previous allergic reactions to similar medicines.
Children
Divalrex 500 Tablet 10 should be given to children below 18 years of age only under medical supervision. Always consult your doctor first.
Older Patients
Older patients may be more susceptible to side effects of Divalrex 500 Tablet 10 and might also have liver and kidney concerns. They should use this medicine under medical supervision. Your doctor will guide you based on your health status.
Interactions of Divalrex 500 Tablet 10
Drug-Drug Interactions
Divalrex 500 Tablet 10 interacts with the following medicines:
- Salicylates: Aspirin and other salicylates may interfere with Divalrex 500 Tablet 10, altering its effectiveness.
- Carbapenem antibiotics: Medications like meropenem and ertapenem can reduce the efficacy of Divalrex 500 Tablet 10.
- Anticonvulsants: Anticonvulsant medications such as phenytoin and phenobarbital could increase the risk of side effects when taken with Divalrex 500 Tablet 10.
- Blood thinners: Blood-thinning medicines like warfarin can lead to increased bleeding risk when used alongside this medication.
- Benzodiazepines: When used with benzodiazepines such as diazepam or lorazepam, Divalrex 500 Tablet 10 may enhance their sedative effects.
- Antidepressants: Antidepressant medicines like fluoxetine and sertraline could interact negatively with this medicine.
Drug-Food Interactions
No known specific food interactions with Divalrex 500 Tablet 10 have been reported.
Drug-Disease Interactions
Divalrex 500 Tablet 10 interacts with the following diseases:
- Liver disease: This medicine should be taken with caution by individuals suffering from liver disease, as it could exacerbate their condition.
- Pancreatic disorders: Individuals with pancreatic disorders should use this medicine cautiously, as it may worsen their symptoms.
- Urea cycle disorders: Patients with urea cycle disorders might experience increased symptoms when taking this medicine.
Dosage of Divalrex 500 Tablet 10
Daily Dose
The daily dose of Divalrex 500 Tablet 10 should be taken exactly as prescribed by your doctor. The dosage may vary depending on personal factors, such as the severity of your condition and your response to the medicine. It’s crucial that you follow this prescribed dosage and don't exceed it without consulting your doctor.
Over Dose
If you happen to take an excess amount of Divalrex 500 Tablet 10, you might experience common symptoms like nausea, dizziness, or drowsiness. If these symptoms persist or become severe, inform your doctor right away.
Missed Dose
If you've missed a dose of Divalrex 500 Tablet 10, take it as soon as you recall. But if it's nearly time for the next dose, skip the missed one and continue with your regular dosage schedule. Please don't increase your dosage without consulting your doctor.
Storage
- Store Divalrex 500 Tablet 10 at a temperature below 30°C.
- Keep the medicine away from light and moisture to maintain its effectiveness.
- Ensure the medicine is kept out of reach of children and pets for safety.
- Always check the expiry date before use.
Special Dietary And Lifestyle Recommendation
- As Divalrex 500 Tablet 10 is used to manage epilepsy, try to maintain a balanced diet. Certain foods may affect your seizures, so consult your doctor about any dietary restrictions.
- If you're managing bipolar disorder with this medicine, regular exercise can help boost your mood. Activities like walking or yoga can make a big difference, but consult your doctor before starting any new fitness regimen.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Epilepsy, Bipolar Disorder, Migraine Prevention |
| Drug Category | Mood Stabiliser |
| Therapeutic Category | Anticonvulsant |
Frequently Asked Questions (FAQs)
Can I take Divalrex 500 Tablet 10 without food?
You can take Divalrex 500 Tablet 10 with or without food. Always follow your doctor's instructions on how to take this medicine.
What if I miss a dose of Divalrex 500 Tablet 10?
If you miss a dose, try to take it as soon as you remember. However, if it's close to your next dose, skip the missed dose and continue your regular schedule.
Can I drink alcohol while using Divalrex 500 Tablet 10?
Avoid alcohol while using this medicine, as it might increase side effects and potentially harm your liver.
How fast does Divalrex 500 Tablet 10 start working?
The time it takes for this medicine to work varies depending on what you take it for. It could take weeks for epilepsy and bipolar disorder and possibly up to three months for preventing migraines.
Can I suddenly stop taking Divalrex 500 Tablet 10?
No, don't stop taking this medicine suddenly. Always consult your doctor for guidance on gradually reducing your dosage to avoid withdrawal symptoms.
Should I take Divalrex 500 Tablet 10 if I'm pregnant?
If you're pregnant, avoid taking Divalrex 500 Tablet 10, as it may cause birth defects or developmental problems in the fetus. Always consult your doctor before starting any medication.
Does Divalrex 500 Tablet 10 interact with other medicines?
Yes, Divalrex 500 Tablet 10 can interact with certain medicines, such as aspirin, antibiotics, anticonvulsants, blood thinners, and others. Let your doctor know about all the other medicines you are currently taking.
What is Divalrex 500 Tablet 10 Tablet used for?
Divalrex 500 Tablet 10 is used to treat epilepsy (seizures), bipolar disorder (mania/mixed episodes), and to prevent migraines. Its active ingredient divalproex stabilizes brain activity and mood, reducing seizure frequency and managing manic symptoms.
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Manufacturer details
M17, Pharma Tower,, Phase-1, Badli Industrial Area,, Badli, Delhi, 110042
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: July 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- U.S. Food and Drug Administration. (n.d.). NDA 20-592/S-019. https://www.fda.gov/media/71427/download. Accessed 1 April 2024.
- Stoner SC, Dahmen MM. Extended-release divalproex in bipolar and other psychiatric disorders: A comprehensive review. Neuropsychiatr Dis Treat. 2007 Dec;3(6):839-46. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656326/
- Schwartz TL, Massa JL, Gupta S, Al-Samarrai S, Devitt P, Masand PS. Divalproex Sodium Versus Valproic Acid in Hospital Treatment of Psychotic Disorders. Prim Care Companion J Clin Psychiatry. 2000 Apr;2(2):45-48. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC181204/
- Valproic acid: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682412.html
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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