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CompositionClopivas AP 150 Tablet is used to prevent serious heart attacks, strokes, and other cardiovascular events in individuals at high risk. It is a class of antiplatelet agents (combining Clopidogrel 75 mg and Aspirin 150 mg). Both components work synergistically to inhibit the formation of blood clots, making it crucial for managing conditions like acute coronary syndrome and unstable angina, and for preventing clots after certain cardiac procedures like stenting.
Clopivas AP 150 Tablet is used for the prevention of heart attacks and strokes, especially for individuals at high risk or with a history of such events. It also helps manage acute coronary syndrome and unstable angina, and prevents blood clots after procedures like coronary artery bypass graft and percutaneous coronary intervention.
Here's how you should take Clopivas AP 150 Tablet:
Swallow the tablet whole, without crushing, chewing, or breaking it.
You can take this medicine with or without food.
It's crucial to take this medicine regularly as directed by your doctor for optimal benefits.
Don't stop taking this medicine without consulting your doctor first.
Clopivas AP 150 Tablet is taken orally.
Clopivas AP 150 Tablet may cause gastrointestinal disturbances (stomach discomfort, bloating, gas), bleeding (nosebleeds, gum bleeding), bruising, dizziness, and headache.
Most side effects are temporary and generally harmless, and they resolve when you discontinue using Clopivas AP 150 Tablet. However, if you experience serious side effects or worsening symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Gastrointestinal disturbances: Try taking Clopivas AP 150 Tablet with food to reduce stomach discomfort.
Dizziness: Consider taking this medicine at night to manage this effect.
Clopivas AP 150 Tablet contains two active ingredients:
Aspirin (150 mg): Aspirin acts by irreversibly inactivating enzymes called cyclooxygenases (COX), which are involved in the production of substances known as prostaglandins and thromboxanes. These substances cause platelets in your blood to clump together, a process known as aggregation. By inhibiting their production, aspirin effectively reduces platelet aggregation.
Clopidogrel (75 mg): This is classified as a prodrug, meaning it needs to be activated by certain enzymes in your body (predominantly CYP2C19) before it takes effect. After activation, clopidogrel forms a metabolite that prevents a substance called ADP from binding to its receptor found on platelets. This action helps inhibit platelet aggregation, reducing the likelihood of clot formation.
Clopivas AP 150 Tablet may cause harm to the unborn baby, especially in the third trimester. If you're pregnant or planning to conceive, it's best to consult your doctor prior to taking this medicine.
Breastfeeding while taking Clopivas AP 150 Tablet is generally not advised. It's recommended to discuss with your doctor to understand potential risks and benefits.
While taking Clopivas AP 150 Tablet, you're advised to limit alcohol consumption. Alcohol can increase the risk of stomach bleeding.
If you have liver issues, particularly severe liver impairment, caution is advised before starting Clopivas AP 150 Tablet. Discuss this with your doctor who can assess if this medicine is suitable for you.
People with kidney conditions should exercise caution before using Clopivas AP 150 Tablet. It's advisable to consult your doctor if you have any history of kidney issues.
Clopivas AP 150 Tablet may cause dizziness. If affected, avoid driving or operating machinery until you feel well again.
If you are allergic to aspirin, clopidogrel or any other components of Clopivas AP 150 Tablet, avoid taking this medicine.
This medicine isn't typically given to children under 18 years of age. Always consult your doctor before giving any medication to a child.
Older patients should take Clopivas AP 150 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Clopivas AP 150 Tablet interacts with the following medicines:
Anticoagulants: Medicines like warfarin and heparin may interact with Clopivas AP 150 Tablet, potentially increasing the risk of bleeding.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): When taken with this tablet, NSAIDs such as ibuprofen and naproxen can increase the risk of gastrointestinal bleeding and reduce the antiplatelet efficacy of aspirin.
Antidepressants: Medicines like fluoxetine and venlafaxine can potentially increase your risk of bleeding when taken with Clopivas AP 150 Tablet.
Antacids: Medicines like omeprazole and esomeprazole can reduce the antiplatelet efficacy of clopidogrel when used concomitantly with this tablet.
There are no specific known food interactions with Clopivas AP 150 Tablet.
Clopivas AP 150 Tablet interacts with the following diseases:
Gastrointestinal bleeding or ulcer: If you have a history of these conditions, you might experience an increased risk of bleeding when using this medicine.
Bleeding disorders: Patients suffering from any bleeding disorders need to be cautious, as it may exacerbate the condition.
Severe liver or kidney impairment: The use of Clopivas AP 150 Tablet in patients with severe liver or kidney disease could lead to increased medicine levels in the body.
The daily dose of Clopivas AP 150 Tablet should be as advised by your doctor. Your dosage could vary based on your health condition and how well you respond to the medicine. Sticking to the prescribed dosage and not exceeding it without consulting your doctor is crucial.
Taking more than the recommended dose of Clopivas AP 150 Tablet may lead to common side effects such as nausea, vomiting, or abdominal pain. If you experience discomfort after taking this medication, you should inform your doctor.
If you forget to take your Clopivas AP 150 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your normal schedule. Never increase your dosage without consulting your doctor.
Store Clopivas AP 150 Tablet at room temperature.
Keep this medicine in a dry place, away from direct sunlight and moisture.
Always keep the tablet out of reach of children.
Ensure to use the medicine before its expiry date.
If you're taking Clopivas AP 150 Tablet, try to eat a balanced diet that's low in saturated fats and cholesterol. This can help reduce your risk of heart disease and stroke, which this medicine helps manage.
Limit alcohol intake. Alcohol can increase the risk of bleeding, a potential side effect of Clopivas AP 150 Tablet.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Heart attacks, Strokes, Acute coronary syndrome |
| Drug Category | Antiplatelet Agents |
| Therapeutic Category | Cardiovascular Medication |
It is useful in preventing heart attacks, strokes, and managing acute coronary syndrome amongst high-risk individuals.
It comprises aspirin and clopidogrel that reduce platelet aggregation, hence decreasing the chances of blood clot formation.
Take the tablet daily, orally, with or without food. Swallow it whole, without crushing, chewing, or breaking it.
Common side effects may include gastrointestinal disturbances, bleeding, bruising, dizziness, and headache.
Its use during pregnancy or breastfeeding may not be safe. Please consult your doctor before taking it.
Yes, inform your doctor about its usage before any surgical procedures and avoid if you have a history of severe bleeding disorders.
Avoid consuming alcohol while on this medication and consult your doctor regarding dietary restrictions.
Check out Editorial Policy
Unknown. (n.d.). Summary of Product Characteristics (Product Data Sheet) (pp. 81–83). https://rwandafda.gov.rw/wp-content/uploads/2023/03/Instaclop-Plus-Clopidogrel-75-mg-and-Aspirin-75-mg-Capsules-SmPC.pdf
Clopidogrel: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00758
Aspirin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00945
Payne, D. A., Hayes, P. D., Jones, C. I., Belham, P., Naylor, A. R., & Goodall, A. H. (2002). Combined therapy with clopidogrel and aspirin significantly increases the bleeding time through a synergistic antiplatelet action. Journal of Vascular Surgery, 35(6), 1204–1209. https://doi.org/10.1067/mva.2002.122027
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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