Canditral 200mg Capsule 4

Glenmark Pharmaceuticals Ltd.

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Composition

Itraconazole (200 Mg)

Strength:

200 MG 100 MG

Canditral 200 Capsule is primarily used to manage various fungal infections. It is an antifungal medication that belongs to the azole class of medicines, which are known for their potency against a range of fungal pathogens.

In addition to its main use, this medicine helps manage fungal infections in different parts of your body, such as the lungs (pulmonary aspergillosis), fingernails and toenails (onychomycosis), mouth and throat (oropharyngeal candidiasis), and the oesophagus (oesophageal candidiasis).

It's crucial that you take this medicine as directed by your doctor. Before starting this medicine, inform your doctor about any pre-existing health conditions or any medications you might be on. If you notice any side effects while using this medicine, immediately report them to your doctor. It's crucial to continue taking the medication for the duration prescribed by your doctor for optimal results.

Canditral 200 Capsule is used for:

Managing fungal infections in the lungs, also known as pulmonary aspergillosis
Managing fungal infections in the fingernails and toenails, a condition called onychomycosis
Controlling fungal infections of the mouth and throat, termed oropharyngeal candidiasis
Managing fungal infections in the oesophagus, which is known as oesophageal candidiasis

Directions for Use of Canditral 200mg Capsule 4

Here are some instructions to follow while taking Canditral 200 Capsule:

Swallow the capsule whole with a full meal to aid its absorption.
Avoid breaking open, chewing, or crushing the capsule.
Continue taking this medicine for the full duration recommended by your doctor, even if symptoms improve.
If you have any doubts or concerns about your medication, it's always wise to consult your doctor.

Canditral 200 Capsule is taken orally.

Side Effects of Canditral 200mg Capsule 4

Canditral 200 Capsule may have the following common side effects:

Nausea
Diarrhoea
Abdominal pain
Headache
Dizziness
Rash
Fatigue

Managing the Side Effects:

Most side effects are temporary, generally mild, and resolve upon discontinuing the use of Canditral 200 Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Canditral 200 Capsule with food to lessen this effect.
Abdominal pain: If you experience stomach discomfort after taking this medicine, consider taking it after a meal.

Canditral 200 Capsule contains itraconazole (200 mg), which acts on your body in the following ways:

Inhibition of ergosterol synthesis: Itraconazole works by inhibiting the synthesis of ergosterol, a vital component in the cell membrane of fungi.
Increase in cell membrane permeability: Due to the disruption in ergosterol synthesis, the cell membrane of the fungi becomes more permeable or leaky. This leads to a loss of essential cellular components.
Fungal cell death: The increased permeability eventually causes the death of the fungal cells, thereby helping manage your infection.

Pregnancy

Canditral 200 Capsule is not recommended for use during pregnancy, especially for nail fungus. If you are pregnant or planning to conceive, it's best to discuss this with your doctor before starting this medicine.

Breastfeeding

Consult your doctor before taking this medicine if you are breastfeeding.

Alcohol

It's always wise to consult your doctor about alcohol consumption while on medication, as alcohol can worsen the side effects of this medicine, like dizziness.

Liver

If you have a history of liver disease or impairment, be cautious while taking Canditral 200 Capsule. This medicine is metabolised by the liver, so it's advisable to discuss your liver health with your doctor before starting this medicine.

Kidney

Canditral 200 Capsule is eliminated mainly by the kidneys. If you have kidney problems, discuss them with your doctor before starting this medication.

Using Machines & Driving

Canditral 200 Capsule may cause dizziness or blurred vision. Avoid driving or operating heavy machinery until you know how this medicine affects you.

Allergy

If you are allergic to itraconazole or any other ingredients in Canditral 200 Capsule, avoid taking this medicine. Discuss your allergies with your doctor beforehand.

Children

Canditral 200 Capsule is meant for adult use only. It's not recommended to give this medication to children under 18 years of age without medical supervision.

Older Patients

Older patients should take Canditral 200 Capsule under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Canditral 200mg Capsule 4

Drug-Drug Interactions

Canditral 200 Capsule interacts with the following medicines:

Gastrointestinal (GI) acid reducers: Antacids such as aluminium hydroxide; H2 blockers like ranitidine; and proton pump inhibitors like omeprazole and rabeprazole may decrease the absorption of itraconazole in the body, reducing its effectiveness.
Medications metabolised by CYP3A4 enzymes: Itraconazole may increase the levels of statins like atorvastatin and rosuvastatin, calcium channel blockers like amlodipine and verapamil, and benzodiazepines like alprazolam and diazepam. This could lead to enhanced and more intense side effects.
Medications that prolong the QT interval: Medicines such as quinidine and dofetilide can interact with itraconazole, increasing the risk of an irregular heartbeat.

Drug-Food Interactions

Canditral 200 Capsule has known interactions with certain foods:

Acidic beverages: Drinking acidic beverages like cola can increase the absorption of itraconazole.

Drug-Disease Interactions

Canditral 200 Capsule interacts with the following diseases:

Heart problems: Itraconazole may cause or worsen heart failure. If you have a history of cardiac issues, caution is advised.
Liver disease: Since itraconazole is metabolised by the liver, people with liver disease should use this medication cautiously.
Kidney disease: As itraconazole is excreted by the kidneys, caution should be exercised in patients with kidney disease.

Daily Dose

The daily dose of Canditral 200 Capsule will be determined according to your doctor's prescription. This dosage may vary depending on factors such as the severity of your condition and your response to the medicine. Always adhere to the prescribed dosage and refrain from exceeding it without consulting your doctor.

Over Dose

In case of an accidental overdose, you may experience common side effects such as nausea, vomiting, abdominal pain, or headache in a more intense form. If these symptoms persist or worsen, inform your doctor immediately.

Missed Dose

Should you miss a dose of Canditral 200 Capsule, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust or increase your dosage without consulting your doctor.

Store your Canditral 200 Capsule at room temperature in a cool, dry place.
Keep it protected from excessive heat and light.
Always ensure the medicine is kept out of reach of children.
Ensure you use this medicine before the expiration date mentioned on the pack.

If you're using Canditral 200 Capsule to manage pulmonary aspergillosis, avoid areas with dust or mould to prevent the condition from worsening.
For those dealing with fungal infections like onychomycosis, maintain good hygiene practices for your nails. Keep them clean and dry to fight off fungal growth. Regularly change your socks and shoes if they get damp.

Fact Box

Drug Category	Ergosterol Synthesis Inhibitor
Therapeutic Category	Antifungal
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Pulmonary Aspergillosis, Onychomycosis, Oropharyngeal Candidiasis

What is Canditral 200 Capsule used for?

Canditral 200 Capsule is used for managing fungal infections in different areas of the body, like the lungs, nails, mouth, and throat.

How does Canditral 200 Capsule work?

It contains itraconazole, which inhibits the growth of fungi by disrupting their cell membranes, aiding in managing the infection.

Should I discontinue Canditral 200 Capsule if my symptoms improve?

No, you should continue taking Canditral 200 Capsule for the full course prescribed by your doctor to ensure optimal results.

Can pregnant women take Canditral 200 Capsule?

Pregnant women should avoid Canditral 200 Capsule unless really needed and recommended by a doctor.

What precautions should I take while using Canditral 200 Capsule?

Inform your doctor about your medical history, especially of heart problems and liver or kidney disease. Also, mention all other medicines you're currently taking.

What are some common side effects of Canditral 200 Capsule?

Common side effects include nausea, vomiting, headache, rash, and fatigue. If any severe symptoms occur, consult your doctor immediately.

How should I store my Canditral 200 Capsule?

Store your capsules at room temperature, away from excess heat and moisture. Keep them out of reach of children.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Glenmark House, HDO-Corporate Building, Wing-A, B.D. Sawant Marg, Chakala Off. Western Express Highway, Andheri (East), Mumbai, Maharashtra, 400099 India

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2018, Dec). Tolsura label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208901s000lbl.pdf
U.S. Food and Drug Administration. (2018, Dec). Tolsura - other review. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/208901Orig1s000OtherR.pdf
DrugBank Online. (2024, May 17). Itraconazole. https://go.drugbank.com/drugs/DB01167
AHFS Patient Medication Information. (2023, Apr 15). Itraconazole: MedlinePlus drug information. MedLine. https://medlineplus.gov/druginfo/meds/a692049.html
Tripathi, K. D. (2013). Antifungal Drugs. In Essentials of Medical Pharmacology (7th ed., p. 794).
Kurn, H., & Wadhwa, R. (2022, April). Itraconazole. In StatPearls [Internet]. NIH National Library of Medicine, National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK557874/
De Beule, K., & Van Gestel, J. (2001). Pharmacology of itraconazole. Drugs, 61 Suppl 1, 27–37. https://doi.org/10.2165/00003495-200161001-00003

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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