Bivamax 250 Mg Injection 1

BIVAMAX 250 MG INJECTION 1 is used in adults undergoing PCI for safe anticoagulation, particularly in heparin-sensitive patients.

Uses of BIVAMAX 250 MG INJECTION 1 are:

• PCI Anticoagulation: Prevents coronary clots during angioplasty and stenting.

• HIT Management: Provides a safe alternative to anticoagulation in heparin-induced thrombocytopenia.

Follow these instructions when BIVAMAX 250 MG INJECTION 1 is administered:

• This medicine is administered by medical professionals in hospital settings only.

• The medicine should not be mixed with other medicines in the same intravenous line.

• The reconstituted solution should be clear and colourless.

• Healthcare staff will monitor your blood clotting parameters during administration.

BIVAMAX 250 MG INJECTION 1 is administered intravenously.

BIVAMAX 250 MG INJECTION 1 contains bivalirudin (250 mg), which works on the body as follows:

• Direct Thrombin Inhibition: Bivalirudin selectively and reversibly binds to thrombin, a key enzyme in blood clotting, preventing it from performing its normal function in the clotting process.

• Fibrinogen Conversion Prevention: It blocks thrombin from converting fibrinogen (a protein in blood plasma) to fibrin, which is essential for forming stable blood clots.

• Coagulation Factor Inhibition: Bivalirudin inhibits thrombin-mediated activation of several coagulation factors, including factors V, VIII, and XIII, which are necessary for proper blood clot formation.

• Platelet Aggregation Reduction: It prevents thrombin-induced platelet aggregation, where platelets clump together, which is an important step in the formation of blood clots.

• Store BIVAMAX 250 MG INJECTION 1 vials at 20-25°C, protected from light in the original carton.

• Keep reconstituted solutions at room temperature and use within 24 hours.

• Do not freeze or expose to excessive heat.

• Store all medicines out of reach of children.

• Do not use after the expiry date printed on the packaging.

• Maintain a heart-healthy diet low in saturated fats and sodium to reduce your risk of atherosclerosis (narrowing of arteries).

• Regular moderate physical activity, as recommended by your doctor, may help improve heart health and circulation when managing conditions requiring anticoagulation therapy.