The active ingredient in Angispan-TR Capsule is nitroglycerin/glyceryl trinitrate.
Nitroglycerin/glyceryl trinitrate works by relaxing the smooth muscles within the blood vessels. This relaxation leads to the widening of blood vessels, which improves blood supply to the muscles of the heart. By improving blood flow, it helps relieve chest pain associated with angina pectoris.
The chemical and physiological processes involved include:
- Nitroglycerin/glyceryl trinitrate releases nitric oxide in the body.
- Nitric oxide then activates an enzyme called guanylate cyclase.
- Guanylate cyclase increases levels of cyclic guanosine monophosphate (cGMP).
- Increased cGMP causes the relaxation of smooth muscles in blood vessel walls.
- Relaxed blood vessels allow for improved blood flow to the heart muscles.
By widening blood vessels and improving blood supply, Angispan-TR Capsule helps relieve chest pain and reduce blood pressure associated with angina pectoris.