Zytanix 2.5 Tablet 15

Zydus Healthcare Ltd

STRIP of 15 Units
STRIP of 10 Units

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MRP ~~₹342.92~~

₹274.34

₹22.86/Units

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Composition

Metolazone (2.5 Mg)

Strength:

5 MG 2.5 MG

Zytanix 2.5 Tablet is used to treat high blood pressure and swelling (edema) caused by heart failure, kidney disease, or liver problems. It works as a diuretic, helping the body remove excess salt and water, which reduces strain on the heart and improves breathing. Regular use helps control blood pressure and lowers health risks.

This medicine can also be employed in managing high blood pressure, thereby reducing the risk of heart disease and strokes. It is beneficial in conditions where the body retains more water than it needs, such as in liver cirrhosis and some kidney disorders.

Before you start taking this medicine, ensure that your doctor knows about any pre-existing conditions or ongoing medications. If you notice any unusual reactions while on this medicine, inform your doctor promptly. For optimal results and to prevent health complications, it's essential to continue taking the medicine for the duration prescribed by your doctor.

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Zytanix 2.5 Tablet is used to manage high blood pressure, fluid retention (oedema), and symptoms of congestive heart failure. It also helps control fluid retention related to kidney disease and reduces swelling and bloating caused by liver disease.

Here's how you should take Zytanix 2.5 Tablet:

Swallow the tablet whole with a glass of water.
Avoid breaking, crushing, or chewing the tablet.
Always take the medicine at the same time each day for best results.
Do not stop taking this medicine without consulting your doctor, even if you feel better.

Zytanix 2.5 Tablet is taken orally.

Zytanix 2.5 Tablet may cause the following side effects:

Nausea
Weakness
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, and resolve upon discontinuing the use of Zytanix 2.5 Tablet. However, if you feel any serious side effects or worsening of any symptoms, please consult your doctor.

Here are some tips for managing some side effects:

Nausea: Try taking Zytanix 2.5 Tablet with a small meal or snack.
Weakness: If you feel weak after taking the medicine, it might be better to take it at bedtime.

Zytanix 2.5 Tablet contains metolazone (2.5 mg), which works on the body as follows:

Diuretic Action: Metolazone acts as a diuretic, which means it helps your kidneys remove extra water and salt from your body through urine.
Reduction of Fluid Retention: By facilitating the excretion of excessive salt and water, metolazone effectively reduces fluid buildup in the body.
Blood Pressure Reduction: The reduced volume of fluid in your blood vessels leads to lower blood pressure levels, thus helping manage hypertension effectively.

Pregnancy

Caution is advised while taking Zytanix 2.5 Tablet if you are pregnant or planning to conceive. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, Zytanix 2.5 Tablet should be used with caution. Your doctor can provide the best advice on whether this medication is suitable for you.

Alcohol

You should be careful when consuming alcohol while on Zytanix 2.5 Tablet as it may intensify the side effects of the medicine. Consulting your doctor would be a sensible course of action.

Liver

Zytanix 2.5 Tablet should be used with caution if you have liver issues. This medicine may affect liver function, so always discuss any liver-related concerns with your doctor before starting this medicine.

Kidney

Zytanix 2.5 Tablet is often prescribed to manage kidney conditions, but always inform your doctor if you have a history of kidney problems before using this medication.

Using Machines & Driving

This medicine might cause dizziness or fatigue. If you experience these symptoms, avoid driving or operating heavy machinery until they subside.

Allergy

If you are allergic to metolazone or any other ingredients in Zytanix 2.5 Tablet, it is advised not to take this medicine without consulting your doctor first.

Children

Zytanix 2.5 Tablet should be given to children under medical supervision only, as they may respond differently to it than adults do.

Older Patients

Older patients should use Zytanix 2.5 Tablet under medical supervision as they may be more susceptible to its side effects, especially liver and kidney issues, due to other medications they might be taking. Always consult your doctor who will guide you based on your health status.

Drug-Drug Interactions

Zytanix 2.5 Tablet interacts with the following medicines:

Antihypertensives: Using Zytanix 2.5 Tablet with medicines like lisinopril or amlodipine can increase the risk of low blood pressure (hypotension).
Diuretics: If taken with furosemide or hydrochlorothiazide, Zytanix 2.5 Tablet may amplify their diuretic effect, resulting in excessive loss of water from the body.
Anti-diabetic medicines: The diuretic effect of Zytanix 2.5 Tablet can affect your blood glucose levels, potentially reducing the effectiveness of anti-diabetic medicines like metformin.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Medicines such as ibuprofen and naproxen may reduce the diuretic and blood pressure-lowering effects of Zytanix 2.5 Tablet when taken together.

Drug-Food Interactions

High-sodium foods can interact with Zytanix 2.5 Tablet:

High-sodium foods: Consuming foods rich in sodium while taking this medicine may counteract its blood pressure-lowering effect.

Drug-Disease Interactions

Zytanix 2.5 Tablet interacts with the following diseases:

Kidney disease: Patients with kidney disease should use this medicine cautiously, as it could affect kidney function further.
Gout: This medicine might increase uric acid levels, potentially triggering a gout attack in susceptible individuals.
Diabetes: As this tablet can impact blood sugar control, frequent monitoring of glucose levels is necessary for diabetic patients on this medication.
Liver disease: Caution is advised for individuals with liver disease, as the medication could exacerbate their condition.

Daily Dose

The daily dose of Zytanix 2.5 Tablet should be as per your doctor's recommendation. This can vary depending on the severity of your condition and how you respond to the medicine. Always adhere to your prescribed dosage and avoid exceeding it without consulting your doctor. For further details regarding dosage instructions, read the package insert.

Over Dose

If you accidentally take more Zytanix 2.5 Tablets than prescribed, you might experience symptoms like dizziness or fainting due to low blood pressure. If these symptoms persist, inform your doctor.

Missed Dose

If you forget to take Zytanix 2.5 Tablet at the scheduled time, take it as soon as you remember. However, if it's time for your next dose, stick to your regular schedule and skip the missed one. Never adjust the dosage without speaking to your doctor.

Keep your Zytanix 2.5 Tablet in its original packaging to protect it from moisture.
Store the medicine at room temperature, ideally below 30 degrees Celsius.
Do not expose the tablet to direct sunlight.
Always keep this medication out of reach of children.

If you're taking Zytanix 2.5 Tablet, try to limit your salt intake as this medicine is often prescribed to manage conditions related to fluid retention and high blood pressure. Excessive salt can worsen these conditions.
Engage in regular physical activity, such as walking or cycling. This helps improve your body's ability to control fluid levels and maintain a healthy blood pressure, supporting the effectiveness of the medicine.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Oedema
Drug Category	Diuretic
Therapeutic Category	Antihypertensive

What is Zytanix 2.5 Tablet used for?

Zytanix 2.5 Tablet is primarily used to manage high blood pressure and fluid retention in people with heart, liver, or kidney disease.

How should I take Zytanix 2.5 Tablet?

Zytanix 2.5 Tablet is taken orally, as directed by your doctor. Always follow the dosage instruction given by your doctor.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it's time for the next dose, continue with your schedule and skip the missed one.

What are the side effects of Zytanix 2.5 Tablet?

Some people may experience dizziness, lightheadedness or stomach upset. If these symptoms persist or worsen, consult your doctor immediately.

Is it safe to consume alcohol while taking Zytanix 2.5 Tablet?

Drinking alcohol may increase certain side effects of Zytanix 2.5 Tablet such as dizziness and light-headedness. It's recommended to avoid alcohol.

Can Zytanix 2.5 Tablet be taken during pregnancy or while breastfeeding?

Always consult your doctor before taking any medicine during pregnancy or breastfeeding, including Zytanix 2.5 Tablet.

How should I store Zytanix 2.5 Tablet?

Store Zytanix 2.5 Tablet at room temperature away from moisture and heat; out of sight and reach of children.

Last Updated On 01 Sep. 2025 | 8:01AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Zydus Tower, Satellite Cross Roads, Sarkhej - Gandhinagar Highway, Ahmedabad Ahmedabad GJ 380015 IN

Country of origin: INDIA

Expiry on or after: January 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Metolazone: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682345.html
Bond, G., Adnan, G., Dua, A., Singh, K., & Crew, C. M. (2023, August 28). Metolazone. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK534203/
Sica, D. A. (2003). Metolazone and its role in edema management. Congestive Heart Failure, 9(2), 100–105. https://doi.org/10.1111/j.1527-5299.2003.01907.x
Metolazone: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00524
Metolazone. (2016). In Elsevier eBooks (p. 982). https://doi.org/10.1016/b978-0-444-53717-1.01074-x

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