Tacvido Ointment 20gm is used to manage moderate to severe atopic dermatitis (eczema) in adults. It contains tacrolimus, a calcineurin inhibitor from the macrolide class of immunosuppressive medicines, and is generally prescribed when other treatments have not worked well or are unsuitable.
Tacrolimus works by calming an overactive immune response in the skin, which reduces the inflammation, redness and itching that occur in eczema, without the thinning effects associated with long-term steroid use.
Apply a thin layer to the affected skin as prescribed as your doctor directs, gently rubbing it in until absorbed, and wash your hands afterwards unless the hands are being treated. Use only on affected areas and avoid covering the skin tightly (occlusive dressings) unless advised.
Avoid excessive sun exposure and use sun protection on treated areas, as the skin may become more sensitive to sunlight. Tell your doctor if the treated skin shows signs of infection, such as increasing redness, warmth or pus, and avoid applying to broken or infected skin.
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Tacvido Ointment 20Gm
Tube of 20 GM
Old MRP ₹253
MRP ₹237.19
₹199.24
₹11.86/GM
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15 days Easy returns
Prescription required for this medicine
Store Below 25°C
CompositionAbout Tacvido Ointment 20Gm
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Uses of Tacvido Ointment 20Gm
Tacvido Ointment 20gm is used to manage moderate to severe atopic dermatitis in adults.
Uses of Tacvido Ointment 20gm are:
- Eczema Relief: Relieves itching, redness, swelling and dryness associated with atopic dermatitis.
- Second-Line Treatment: Used when other eczema treatments have not been effective or are not suitable for continued use.
Directions for Use of Tacvido Ointment 20Gm
Here's how to apply Tacvido Ointment 20gm correctly:
Ensure that the ointment area is clean and dry before application.
Apply a thin layer of the ointment gently to the affected skin area as prescribed by your doctor.
Rub the ointment gently and completely on the skin until it is fully absorbed.
Continue applying as advised by your doctor until signs of atopic dermatitis resolve.
If symptoms persist beyond 6 weeks or worsen, consult your doctor immediately.
Route of Administration
Tacvido Ointment 20gm is applied topically.
Side Effects of Tacvido Ointment 20Gm
Tacvido Ointment 20gm may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Tacvido Ointment 20gm are:
- Application Site: A burning or tingling sensation at the site of application, especially during the first few days.
- Skin: Acne or inflammation of the hair follicles may occur.
- General: Headache may occur in some people.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve upon discontinuing Tacvido Ointment 20gm. However, if you experience serious side effects or worsening symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Application site reactions: If you feel discomfort at the application site, try applying a cold compress to soothe the area.
Acne: Maintaining good skin hygiene can help manage acne; wash your face gently with mild soap and warm water twice daily.
How Tacvido Ointment 20Gm Works?
Tacvido Ointment 20gm contains tacrolimus (0.03%), which acts on the body as follows:
Binding to FKBP-12: Tacrolimus first binds with an intracellular protein named FKBP-12.
Inhibition of Calcineurin: The complex formed by tacrolimus and FKBP-12 inhibits calcineurin, an enzyme that relies on calcium and calmodulin.
Prevention of NFAT Dephosphorylation: By inhibiting calcineurin, tacrolimus prevents dephosphorylation and translocation of NFAT (Nuclear Factor of Activated T-cells), a key component in the production of inflammatory cytokines.
Safety Measures & Warnings
Pregnancy
If you are pregnant or planning to conceive, discuss this with your doctor before starting Tacvido Ointment 20gm.
Breastfeeding
The use of Tacvido Ointment 20gm while breastfeeding has not been thoroughly studied. It is best to consult your doctor if you are lactating before using this medicine.
Alcohol
If you consume alcohol while using this medicine, you might experience a heat sensation or redness in your face. Talk to your doctor about any concerns.
Liver
Even though systemic absorption of Tacvido Ointment 20gm is minimal, caution is advised if you have severe liver disease. Discuss your liver health with your doctor before using this medicine.
Kidney
As with liver health, the systemic absorption of Tacvido Ointment 20gm into the bloodstream is quite low. However, if you have severe kidney problems, consult your doctor before applying this ointment.
Use In Driving And Operating Machinery
Tacvido Ointment 20gm application is unlikely to affect your ability to drive or use machines as it's a topical medication.
Allergy
Do not apply Tacvido Ointment 20gm if you're allergic to tacrolimus or any other ingredients in the formulation. Always inform your doctor about any known allergies before starting this medicine.
Children
Tacvido Ointment 20gm should not be used on children under 2 years of age. For children above 2, it's best to consult a doctor before application.
Older Patients
Older patients should use Tacvido Ointment 20gm under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients above 70 due to potential liver and kidney issues. Your doctor will guide you based on your health status.
Interactions of Tacvido Ointment 20Gm
Drug-Drug Interactions
Tacvido Ointment 20gm interacts with the following medicines:
Immunosuppressive agents: Medicines like corticosteroids (cortisone) could potentially enhance the immunosuppressive effects of Tacvido Ointment 20gm.
Drug-Food Interactions
There are no known food interactions with Tacvido Ointment 20gm. As it's applied topically, what you eat or drink isn't likely to affect the medication's action.
Drug-Disease Interactions
Tacvido Ointment 20gm interacts with the following diseases:
Netherton's Syndrome: This skin disorder can weaken the skin barrier, possibly leading to increased absorption of Tacvido Ointment 20gm.
Liver Disease: As tacrolimus is metabolised in the liver, patients with liver disease should use this ointment cautiously.
Severe Renal Impairment: Although systemic absorption is minimal, caution is advised in patients with severe renal impairment.
Dosage of Tacvido Ointment 20Gm
Daily Dose
The daily application of Tacvido Ointment 20gm should be as directed by your doctor. This could vary based on factors like the severity of your condition and how you respond to the ointment. Always adhere to the prescribed dosage and don’t use more without consulting your doctor.
Over Dose
If you accidentally apply too much Tacvido Ointment 20gm, you might experience some side effects such as skin redness or itching. In such cases, wash off the excess ointment gently with water. If symptoms persist, inform your doctor.
Missed Dose
If you miss an application of Tacvido Ointment 20gm, apply it as soon as you remember. But if it's almost time for your next scheduled application, simply skip the missed one and continue with your regular schedule. Never increase the number of applications without consulting your doctor.
Storage
Store Tacvido Ointment 20gm at room temperature below 30°C.
Keep away from direct sunlight and heat.
Do not be exposed to moisture or excessively dry conditions.
Keep out of reach of children.
Special Dietary And Lifestyle Recommendation
Regularly moisturise your skin, as dryness can intensify itching and inflammation associated with atopic dermatitis.
Avoid food allergens known to trigger or worsen your eczema symptoms; common ones include dairy products, eggs, nuts and seeds, wheat and gluten.
Fact Box
| Dosage Forms Available | Ointment |
| Habit Forming | No |
| Ailment | Atopic Dermatitis, Eczema |
| Drug Category | Immunosuppressive Agent |
| Therapeutic Category | Dermatological Medicine |
Frequently Asked Questions (FAQs)
What is Tacvido Ointment 20gm used for?
Tacvido Ointment 20gm is used to manage moderate-to-severe atopic dermatitis or eczema in adults who have not responded well to other therapies.
How does Tacvido Ointment 20gm work?
Tacrolimus, the active ingredient, works by suppressing the immune response that causes inflammation and symptoms in atopic dermatitis or eczema.
Can Tacvido Ointment 20gm be used on children?
Yes, Tacvido Ointment 20gm can be used on children aged 2 years and older with a doctor's advice.
Is Tacvido Ointment 20gm safe for long-term use?
Consult your doctor before using this medicine long-term.
Can Tacvido Ointment 20gm be used on the face?
Yes, if affected by atopic dermatitis and advised by the doctor. Avoid contact with eyes and mucous membranes.
Does Tacvido Ointment 20gm cause skin thinning like steroids?
No, unlike topical corticosteroids, Tacvido Ointment 20gm does not cause skin atrophy or thinning with prolonged use.
How long does it take for Tacvido Ointment 20gm to work?
Improvement in atopic dermatitis symptoms is usually seen within 1 week of starting treatment, with maximal benefits after 6 weeks of continuous use.
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Manufacturer details
Country of origin: INDIA
References
Tacrolimus: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00864
Tacrolimus topical: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a602020.html
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 445643, Tacrolimus. Retrieved June 15, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Tacrolimus
Martins, J. C., Martins, C., Aoki, V., Gois, A. F., Ishii, H. A., & Da Silva, E. M. (2015). Topical tacrolimus for atopic dermatitis. Cochrane Library, 2016(10). https://pubmed.ncbi.nlm.nih.gov/26132597/
Araya, A. A., & Tasnif, Y. (2023, May 29). Tacrolimus. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK544318/
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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