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Tacrolimus

Immunosuppressant

Uses of Tacrolimus

  • Tacrolimus is a medication primarily used to treat eczema or atopic dermatitis. It belongs to the class of immunosuppressants and helps reduce inflammation and immune responses in the skin.

Side effects of Tacrolimus

  • Itching
  • Burning sensation
  • Redness
  • Pain
  • Skin tingling

How Tacrolimus works

  • Tacrolimus works by suppressing the immune cells responsible for inflammation and skin swelling. It effectively reduces allergic reactions, redness, swelling, and itching associated with eczema by targeting specific immune cells called T-lymphocytes and inhibiting the release of inflammatory substances. Tacrolimus helps alleviate symptoms such as dryness, peeling, and rashes by controlling the immune response in the skin. It restores balance within the skin’s immune system, promoting healing and reducing symptoms of atopic dermatitis. This targeted action addresses the underlying cause of eczema, providing effective relief.

Certified content

Written By

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Amit SharmaMedical Content Writer| 4 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Medical Content Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Tacrolimus is available for use via the topical route (ointment).

Age and Dose Restrictions

  • This medicine is meant for adults and children above 16 years of age.

Contraindications

  • The medication is not recommended in patients with a known allergy to Tacrolimus.

Other Medications to Avoid

  • Inform your doctor if you are using oral corticosteroids (such as cortisone) or any other topical skin products.

Overdose and Missed Dose

  • An overdose of this medication may cause symptoms like skin sensitivity, burning or tingling sensations, pain, itching, irritation, rash, dryness, peeling, and redness. If you observe these symptoms, inform your doctor and follow the advice accordingly.
  • If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use in Driving and Operating Machinery

  • This medication will not impair your ability to drive and operate heavy machinery.

Use in Pregnancy and Lactation

  • Inform your doctor before using this medicine in pregnancy and during breastfeeding.

Caution in Other Conditions

  • If you have skin tumours, a weakened immune system, Netherton’s syndrome (a rare hereditary disorder affecting hair, skin, and the immune system), lamellar ichthyosis (extensive skin scaling), generalised erythroderma (widespread skin inflammation and redness), swollen lymph nodes, infected lesions, or cutaneous Graft Versus Host Disease (an immune reaction of the skin after a bone marrow transplant), inform your doctor before using Tacrolimus. Also, report any changes in your skin's appearance.

Special Dietary and Lifestyle Recommendations

  • Include foods rich in quercetin, a flavonoid found in apples, cherries, broccoli, spinach, and blueberries. 
  • Consume probiotic-rich foods to help strengthen the immune system against allergies. 
  • Limit foods that may trigger allergies, such as dairy, soy, eggs, and nuts. Avoid excessive sugar intake, as it can worsen inflammation. Maintain a balanced diet with fruits, vegetables, whole grains, healthy fats, and fish. 
  • Protect your skin by avoiding harsh soaps, detergents, cleaning agents, dust, sand, wool, synthetic fibers, and cigarette smoke.

Frequently asked questions

Tacrolimus may start showing improvement in eczema symptoms within a few days to a few weeks. However, the full benefits can take several weeks, depending on the severity of the condition.

Avoid exposure to direct sunlight and UV light, as Tacrolimus may increase skin sensitivity. Do not apply it to infected or broken skin, and inform your doctor if you have a weakened immune system, skin tumors, or any pre-existing skin conditions.

No, do not stop using Tacrolimus abruptly without consulting your doctor. Stopping suddenly may cause symptoms to return or worsen. Follow your doctor’s instructions for tapering or discontinuing the medication.

Tacrolimus is mainly used as a topical treatment for eczema, but if taken orally or systemically, it may affect kidney and liver function. Patients with kidney or liver issues should consult their doctor before using Tacrolimus.

There is no strong evidence that Tacrolimus affects fertility in men or women. However, if you are planning to conceive, discuss it with your doctor for personalised advice.

Terms & Conditions

List of Medicines for Tacrolimus

Pangraf 0.5 Capsule 10
Pangraf 0.5 Capsule 10
Panacea Biotec Ltd
Pack of 10 Units
₹187.43
MRP ₹231.39
19% OFF
Tacroz Forte Xl Ointment 40gm
Tacroz Forte Xl Ointment 40gm
Glenmark Pharmaceuticals Ltd.
Pack of 40 GM
₹800
MRP ₹1000
20% OFF
Tacmod Forte Ointment 30gm
Tacmod Forte Ointment 30gm
La Pristine Bioceuticals Pvt Ltd
Pack of 30 GM
₹472
MRP ₹590
20% OFF
Pangraf 0.25 Capsule 10
Pangraf 0.25 Capsule 10
Panacea Biotec Ltd
Pack of 10 Units
₹123.5
MRP ₹154.38
20% OFF
Pangraf 1.0 Capsule 10
Pangraf 1.0 Capsule 10
Panacea Biotec Ltd
Pack of 10 Units
₹386.7
MRP ₹454.94
15% OFF
Tacroz Forte Ointment 20gm
Tacroz Forte Ointment 20gm
Glenmark Pharmaceuticals Ltd.
Pack of 20 GM
₹624
MRP ₹780
20% OFF
Tacronol Ointment 10gm
Tacronol Ointment 10gm
Knoll Healthcare Pvt. Ltd.
Pack of 10 GM
₹156.34
MRP ₹313.3
50.1% OFF
Tacroz Forte Ointment 10gm
Tacroz Forte Ointment 10gm
Glenmark Pharmaceuticals Ltd.
Pack of 10 GM
₹440
MRP ₹550
20% OFF

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