Tacrokem Ointment 10gm

Tacrokem Ointment 10gm is used for the following:

• Managing moderate-to-severe atopic dermatitis in adults

• Assisting those with atopic dermatitis who haven't responded well to conventional therapies

• Providing relief for symptoms of intense itching, redness, and swelling associated with chronic atopic dermatitis

• Aiding in the reduction of skin dryness, cracking, oozing, and crusting caused by atopic dermatitis

Here's how to apply Tacrokem Ointment 10gm correctly:

• Ensure that the ointment area is clean and dry before application.

• Apply a thin layer of the ointment gently to the affected skin area as prescribed by your doctor.

• Rub the ointment gently and completely on the skin until it is fully absorbed.

• Continue applying as advised by your doctor until signs of atopic dermatitis resolve.

• If symptoms persist beyond 6 weeks or worsen, consult your doctor immediately.

Tacrokem Ointment 10gm is applied topically.

Tacrokem Ointment 10gm contains tacrolimus (0.03%), which acts on the body as follows:

• Binding to FKBP-12: Tacrolimus first binds with an intracellular protein named FKBP-12.

• Inhibition of Calcineurin: The complex formed by tacrolimus and FKBP-12 inhibits calcineurin, an enzyme that relies on calcium and calmodulin.

• Prevention of NFAT Dephosphorylation: By inhibiting calcineurin, tacrolimus prevents dephosphorylation and translocation of NFAT (Nuclear Factor of Activated T-cells), a key component in the production of inflammatory cytokines.

• Store Tacrokem Ointment 10gm at room temperature below 30°C.

• Keep away from direct sunlight and heat.

• Do not be exposed to moisture or excessively dry conditions.

• Keep out of reach of children.

• Regularly moisturise your skin, as dryness can intensify itching and inflammation associated with atopic dermatitis.

• Avoid food allergens known to trigger or worsen your eczema symptoms; common ones include dairy products, eggs, nuts and seeds, wheat and gluten.