Silodal M 25 Tablet 10

Sun Pharmaceutical Industries Ltd

Strip of 10 Units

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MRP ~~₹450~~

₹360

₹45/Units

20% off

*MRP inclusive of all taxes

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Composition

Mirabegron (25 Mg) + Silodosin (8 Mg)

Silodal-M 25 Tablet is used to manage symptoms of benign prostatic hyperplasia (BPH) in men. It helps reduce urinary symptoms like frequent urination and difficulty starting urination by relaxing the muscles in the prostate and bladder. It is a combination medicine that belongs to the class of bladder and prostate disorder treatments.

In addition to managing symptoms of BPH, this medicine also helps alleviate urinary difficulties such as frequent urination, especially at night; weak urine stream; difficulty starting urination; a sensation of incomplete bladder emptying; and sudden urges to urinate.

You should take this medicine orally as directed by your doctor. It's important to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. You should continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Silodal-M 25 Tablet is used for the following:

Managing symptoms related to benign prostatic hyperplasia, a non-cancerous enlargement of the prostate gland in men
Reducing frequent urination, particularly during the nighttime
Easing difficulty in beginning urination and a weak urine stream
Relieving the sensation of incomplete bladder emptying
Controlling sudden urges to urinate.

When using Silodal-M 25 Tablet, follow these steps:

Swallow the medicine whole with a glass of water.
Do not crush or chew the tablet.
Always consult your doctor for specific advice on how to take this medication properly.
Remember, abruptly stopping this medicine without your doctor's agreement may worsen your symptoms.

Silodal-M 25 Tablet is taken orally.

Silodal-M 25 Tablet may have the following common side effects:

Retrograde ejaculation: This is when semen, instead of being expelled out of the body, goes back into the bladder during orgasm.
Dizziness
Headache
Diarrhoea
Nasopharyngitis: This is inflammation of the throat and nasal passages.
Orthostatic hypotension: This refers to a sudden drop in blood pressure when standing up from sitting or lying down.
Nasal congestion

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Silodal-M 25 Tablet. However, if you experience any serious side effects or worsening of symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Silodal-M 25 Tablet with food to lessen this effect.
Orthostatic hypotension: Consider taking this medicine at bedtime to reduce the likelihood of experiencing a sudden drop in blood pressure when standing up.

Silodal-M 25 Tablet contains two active ingredients:

Mirabegron (25 mg): As a beta-3 adrenergic agonist, this ingredient works by relaxing the muscles of your bladder. This action increases the storage capacity of your bladder and reduces episodes of urgency and frequency of urination.
Silodosin (8 mg): This ingredient is an alpha-blocker. It works by relaxing the smooth muscles around your prostate gland and bladder neck. This action facilitates easier urine flow and reduces the symptoms of BPH.

Pregnancy

This medication is not indicated for use in women.

Breastfeeding

This medication is not indicated for use in women.

Alcohol

There is no known interaction between Silodal-M 25 Tablet and alcohol. However, it's always wise to discuss your alcohol consumption with your doctor before starting this medicine.

Liver

Silodal-M 25 Tablet is not recommended for individuals with severe liver impairment. If you have mild to moderate liver problems, consult your doctor before starting this medication.

Kidney

The use of Silodal-M 25 Tablet is contraindicated in individuals with severe kidney impairment. If you've had kidney issues, it's best to consult your doctor before taking this medicine.

Using Machines & Driving

This medication may cause dizziness or a sudden drop in blood pressure upon standing. These side effects could affect your ability to drive or operate machinery safely.

Allergy

If you have known allergies to mirabegron, silodosin, or any other ingredients in Silodal-M 25 Tablet, do not take this medicine. Talk to your doctor about your allergies beforehand.

Children

Silodal-M 25 Tablet is typically not indicated for children under 18 years of age. It's always best to consult a doctor before giving this medicine to a child.

Older Patients

Older patients should take Silodal-M 25 Tablet under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age due to potential liver and kidney issues.

Drug-Drug Interactions

Silodal-M 25 Tablet interacts with the following medicines:

Antifungals: Medicines like ketoconazole and itraconazole may interact with Silodal-M 25 Tablet, potentially affecting the absorption and effectiveness of this medication.
Antiretrovirals: Ritonavir, an antiretroviral medicine, can interact with Silodal-M 25 Tablet, possibly increasing the risk of side effects.
Immunosuppressants: Cyclosporine, an immunosuppressant medicine, may interact with Silodal-M 25 Tablet, potentially altering its efficacy or increasing side effect risks.
Alpha-blockers: Medicines such as tamsulosin and doxazosin, which are other alpha-blockers like silodosin, can interact with Silodal-M 25 Tablet. This could lead to enhanced effects or increased side effects.
Erectile dysfunction medicines: PDE5 inhibitors like sildenafil could interact with Silodal-M 25 Tablet, potentially enhancing their effects and side effects.

Drug-Food Interactions

Drug-Disease Interactions

Silodal-M 25 Tablet interacts with the following diseases:

Liver disease: If you have liver disease, you need to exercise caution while taking Silodal-M 25 Tablet, as it could exacerbate your condition.
Kidney disease: Those with kidney problems should also be cautious while using this medication, as it can impact kidney function further.
Hypertension: Uncontrolled high blood pressure can be a concern while taking Silodal-M 25 Tablet. Regular monitoring is advised during the course of this medication.

Daily Dose

The daily dose of Silodal-M 25 Tablet should be taken as advised by your doctor. It's essential to stick to the prescribed dosage and not modify it without your doctor's permission.

Over Dose

If you've accidentally taken more Silodal-M 25 Tablet than prescribed, you might experience common symptoms like diarrhoea or dizziness. If these problems persist, do inform your doctor.

Missed Dose

If you missed a dose, take it as soon as you remember. But if it's nearly time for your next one, skip the missed dose and continue with your regular schedule.

Store Silodal-M 25 Tablet in a cool, dry place away from direct sunlight and moisture.
The ideal storage temperature is below 30°C.
Avoid storing the medicine in areas of high humidity, such as bathrooms or kitchens.
Always keep this medicine out of sight and out of reach of children.
Remember to use the tablet before its expiry date.

Limiting your intake of caffeine and alcohol, especially before bedtime, can help manage symptoms associated with benign prostatic hyperplasia (BPH), a condition Silodal-M 25 Tablet is prescribed for.
Regular physical activity and maintaining a healthy body weight can also assist in managing BPH symptoms.

Fact Box

Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Benign Prostatic Hyperplasia, Urinary Difficulty
Drug Category	Beta-3 adrenergic agonist, Alpha-blocker
Therapeutic Category	Bladder and Prostate Disorder Treatments

What is Silodal-M 25 Tablet used for?

Silodal-M 25 Tablet is used to manage symptoms of benign prostatic hyperplasia, including frequent urination, weak urine stream, and sudden urges to urinate.

How does Silodal-M 25 Tablet work?

This medicine contains two active components: mirabegron, which relaxes bladder muscles to increase urine storage and reduce urgency, and silodosin, which relaxes prostate and bladder muscles to improve urine flow.

How should I take Silodal-M 25 Tablet?

Take this medicine exactly as your doctor directs. Swallow it whole with water at the same time each day; don't crush, chew, or alter the tablet.

Are there any side effects?

Common side effects include retrograde ejaculation, dizziness, headache, diarrhoea, throat inflammation, sudden blood pressure drop upon standing, and nasal congestion. Consult your doctor if they persist.

Are there any precautions I should take before using Silodal-M 25 Tablet?

Inform your doctor about any allergies to mirabegron or silodosin, other medications you're taking, a history of liver or kidney problems, planned eye surgeries, and high blood pressure.

Can Silodal-M 25 Tablet interact with other medicines?

Yes, it can interact with antifungals like ketoconazole, antiretrovirals like ritonavir, other alpha-blockers, blood pressure medicines, and erectile dysfunction medications. Always inform your doctor about all medicines you are taking.

How should I store my Silodal-M 25 Tablet?

Store the tablet at room temperature (below 30°C) in a cool, dry place away from direct sunlight and moisture. Keep them out of reach of children.

Last Updated On 18 Aug. 2025 | 6:41AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SCO No. 14, Sector 5, Panchkula – 134114, Haryana

Country of origin: INDIA

Expiry on or after: January 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Astellas Pharma US, Inc. (2012). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202611s000lbl.pdf
Mirabegron: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB08893
Watson Pharmaceuticals, Inc. (2013). RAPAFLO prescribing information [Prescribing information]. In RAPAFLO Prescribing Information (pp. 1–22). https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022206s012lbl.pdf
Silodosin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06207

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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