Ranopill 500 Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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Old MRP ₹183.5

MRP ~~₹172.03~~

₹137.62

₹17.2/Units

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Prescription required for this medicine

Store Below 30° C

Composition

Ranolazine (500 Mg)

Ranopill 500 Tablet 10 is used to manage chronic angina. It is a single-ingredient antianginal medicine containing ranolazine.

This medicine reduces the frequency of angina episodes. It is also used when symptoms are not fully controlled by standard anti-anginal treatment.

Before starting, tell your doctor about your medical conditions and allergies. Tell the doctor about all other medicines, supplements or herbal products you take. Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding. Attend any monitoring appointments advised by your doctor. Report persistent or serious side effects to your doctor. Do not stop taking or using the medicine unless your doctor advises you to do so.

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Ranopill 500 Tablet 10 is used to manage chronic angina.

Uses of Ranopill 500 Tablet 10 are:

Chronic Angina: Reduces the frequency of angina episodes.
Add-on Therapy: Used when symptoms are not fully controlled by standard anti-anginal treatment.

Swallow the tablet whole with a glass of water.
Avoid crushing, breaking, or chewing the tablet.
Ensure you do not take more than the recommended dose without consulting your doctor.
Even if symptoms are not bothersome, continue to take this medicine regularly as prescribed for optimal results.
Lastly, it's crucial not to stop taking Ranopill 500 Tablet 10 without speaking to your doctor first.

Ranopill 500 Tablet 10 is taken orally.

Ranopill 500 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Ranopill 500 Tablet 10:

Digestive: constipation and feeling sick (nausea).
Neurological: dizziness and headache.

If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Ranopill 500 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Ranopill 500 Tablet 10 with food or milk to lessen this effect.
Dizziness: Consider taking this medicine at night if it causes dizziness during the day.

Ranopill 500 Tablet 10 contains ranolazine (500 mg), which acts on the body in the following ways:

Reduces Sodium Current: Ranolazine reduces the late sodium current in heart muscle cells, minimising the build-up of sodium within these cells.
Decreases Calcium Overload: By reducing intracellular sodium accumulation, ranolazine indirectly decreases calcium overload in heart muscle cells.
Improves Myocardial Relaxation: Ranolazine promotes better relaxation of myocardial cells (heart muscle cells) by maintaining ionic balance.
Reduces Left Ventricular Stiffness: By improving myocardial relaxation, ranolazine decreases left ventricular stiffness, which is a part of your heart's main pumping chamber. This makes it easier for your heart to pump blood, thus reducing the risk of angina attacks.

Pregnancy

Is it safe to use Ranopill 500 Tablet 10 during pregnancy?

Caution is advised when taking the Ranopill 500 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Is it safe to use Ranopill 500 Tablet 10 during breastfeeding?

The safety and efficacy of Ranopill 500 Tablet 10 in nursing mothers have not been established. It's advisable to discuss this with your doctor before starting this medication.

Alcohol

Is it safe to drink alcohol while using Ranopill 500 Tablet 10?

There's limited data on the interaction of Ranopill 500 Tablet 10 with alcohol. Nonetheless, caution is advised when consuming alcohol while on this medication. It's sensible to consult your doctor for guidance.

Liver

Is it advisable to use Ranopill 500 Tablet 10 when experiencing liver problems?

Ranopill 500 Tablet 10 should be used cautiously in patients with liver impairment. If you have any liver health issues, it's wise to discuss them with your doctor before beginning this medication.

Kidney

Is it advisable to use Ranopill 500 Tablet 10 when experiencing kidney problems?

If you have a history of kidney problems, it's prudent to consult your doctor before starting Ranopill 500 Tablet 10.

Use In Driving And Operating Machinery

Is it safe to operate heavy machinery or drive when using Ranopill 500 Tablet 10?

Ranopill 500 Tablet 10 may cause dizziness, a common side effect. If you experience this, avoid driving or operating heavy machinery until you feel normal again.

Allergy

Are there any specific conditions that should be considered before using Ranopill 500 Tablet 10?

This medicine is not suitable for patients allergic to ranolazine or any other ingredients in the tablet. If you have known allergies, inform your doctor before starting this medication.

Children

Is Ranopill 500 Tablet 10 suitable for infants or children?

The safety and efficacy of Ranopill 500 Tablet 10 in children under 18 years have not been established. It should only be used if potential benefits justify the risks.

Older Patients

Is Ranopill 500 Tablet 10 suitable for older patients?

Older patients should take Ranopill 500 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Ranopill 500 Tablet 10 interacts with the following medicines:

Strong CYP3A Inhibitors: Medicines such as ketoconazole, clarithromycin, and ritonavir can significantly increase the concentration of ranolazine in your blood, which may lead to increased side effects.
Moderate CYP3A Inhibitors: Medicines like diltiazem, verapamil, and certain antibiotics can also raise the levels of ranolazine in your bloodstream.
P-glycoprotein Transported Medications: Taking Ranopill 500 Tablet 10 with medicines like digoxin can increase the latter's levels in your body.

Drug-Food Interactions

Certain foods can interact with Ranopill 500 Tablet 10:

Grapefruit Products: These should be avoided as they can increase the ranolazine levels in your body.

Drug-Disease Interactions

Ranopill 500 Tablet 10 interacts with the following diseases:

Liver Impairment: Patients with liver issues should use this medicine cautiously as it may exacerbate their condition.
Kidney Impairment: Those with kidney problems should also exercise caution while taking this medication.
QT Prolongation: This medicine should be used carefully by those with pre-existing QT prolongation due to the risk of further elongating the QT interval.

Daily Dose

Take your daily recommended dose of Ranopill 500 Tablet 10 as your doctor prescribes. This can vary depending on the severity of your condition and your response to the medicine.

Over Dose

If you accidentally take too much Ranopill 500 Tablet 10, common overdose symptoms might include feeling dizzy or having a headache. If such symptoms persist, consult your doctor.

Missed Dose

If you forgot to take your Ranopill 500 Tablet 10, take it as soon as you remember. If it's almost time for the next dose, skip the missed one. Always consult your doctor before making any changes to your dosage plan.

Store Ranopill 500 Tablet 10 in a cool, dry place below 30°C.
Protect the tablets from moisture and heat.
Always keep the medicine out of children's reach for safety.
Use the medicine before its expiry date, as mentioned on the packaging.

Since Ranopill 500 Tablet 10 is used to manage angina, try adopting a heart-friendly diet. Reduce saturated fats and include more fruits, vegetables, and whole grains.
Regular physical activity can also help. Begin with light activities like walking or cycling, but consult your doctor before starting any new exercise routine.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Chronic Stable Angina Pectoris
Drug Category	Late Sodium Current Reduction
Therapeutic Category	Anti-Anginal Agents

What is Ranopill 500 Tablet 10 used for?

Ranopill 500 Tablet 10 is prescribed to manage chronic stable angina, a type of chest pain caused by reduced blood flow to the heart.

How does Ranopill 500 Tablet 10 work?

Ranopill 500 Tablet 10 reduces sodium and calcium overload in heart cells, improves heart function and reduces oxygen demand, thus managing angina symptoms.

Can I take Ranopill 500 Tablet 10 while on other anti-anginal medicines?

Yes, Ranopill 500 Tablet 10 can be taken alongside other anti-anginal medicines such as beta-blockers or calcium channel blockers, as advised by your doctor.

What should I do if I miss a dose of Ranopill 500 Tablet 10?

If you miss a dose, take it as soon as you remember. If it's almost time for the next dose, skip the missed one.

Can I consume alcohol while taking Ranopill 500 Tablet 10?

It's better to avoid or limit alcohol while taking Ranopill 500 Tablet 10 as it can intensify certain side effects like dizziness and interfere with medicine efficacy.

Are there any dietary restrictions while taking Ranopill 500 Tablet 10?

While there are no specific dietary rules, grapefruit products should be avoided as they can affect how Ranopill 500 Tablet 10 is metabolised in the body.

Can anyone take Ranopill 500 Tablet 10?

No, certain people, like those with severe liver impairment or known hypersensitivity to ranolazine, shouldn't take this medicine. Always consult your doctor first.

Should Ranopill 500 Tablet 10 be taken before or after food?

Ranopill 500 Tablet 10 can be taken with or without food; however, taking it with food is often recommended to improve absorption and reduce the risk of stomach upset. Always follow the dosage and instructions provided by the doctor.

Last Updated On 18 Sep. 2026 | 1:05PM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 10 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 10 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

Expiry on or after: February 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Ranolazine. (n.d.). Medlineplus.Gov. Retrieved August 27, 2024, from https://medlineplus.gov/druginfo/meds/a606015.html
U.S. Food and Drug Administration. (2010). Ranolazine (Ranexa): Highlights of Prescribing Information. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021526s012lbl.pdf
Ranolazine - StatPearls - NCBI bookshelf. (2023, May 16). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK507828/
Ranolazine. (2024, April 9). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00243

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Email: grievance-officer@truemeds.in

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