Strip of 10 Units
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CompositionPrusent 2 Tablet is a gastrointestinal prokinetic agent primarily used to manage chronic idiopathic constipation in adults. It belongs to the class of selective serotonin-4 ($\text{5-HT}_4$) receptor agonists. The active ingredient, prucalopride, stimulates intestinal motility and promotes effective bowel movements when other laxatives fail to provide sufficient relief.
Prusent 2 Tablet used for the management of chronic idiopathic constipation (CIC) in adults. It is typically prescribed when other standard treatments, such as laxatives, have failed to provide sufficient relief. By enhancing bowel movements and increasing intestinal motility (promoting gastric emptying), it helps those who struggle to pass stools regularly and easily without a known cause.
Here are some instructions while taking Prusent 2 Tablet:
Swallow the tablet whole with a glass of water.
You can take this medicine with or without food.
Avoid crushing, chewing or breaking the tablet.
Always take your medicine at the same time each day for optimal results.
Always consult your doctor before changing any aspects of how you take this medicine.
Prusent 2 Tablet is taken orally.
Prusent 2 Tablet may cause side effects such as headache, nausea, vomiting, abdominal pain, diarrhoea, dizziness, fatigue, low appetite and indigestion. If these side effects do not improve, consult your doctor.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Prusent 2 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Try taking Prusent 2 Tablet with food.
Dyspepsia: If you have indigestion, take this medicine after meals to lessen this effect.
Prusent 2 Tablet contains prucalopride (2 mg), which acts on the body as follows:
Activates 5-HT4 Receptors: Prucalopride works by activating specific receptors known as serotonin 5-HT4 receptors in your intestinal walls.
Promotes Gastrointestinal Peristalsis: By activating these receptors, prucalopride indirectly increases the release of acetylcholine, a neurotransmitter that promotes contractions in your intestines. These contractions help move food and waste through your digestive tract more effectively.
Relieves Chronic Constipation: The increased peristalsis and contractions induced by prucalopride effectively restore normal bowel function and provide relief from chronic constipation.
You should exercise caution if you are pregnant and considering Prusent 2 Tablet. It's advisable to consult your doctor prior to taking this medicine.
Prusent 2 Tablet is not recommended for breastfeeding women. Discuss with your doctor the potential risks and benefits before starting this medicine.
It's wise to limit alcohol intake while on Prusent 2 Tablet as it could intensify dizziness, a possible side effect.
If you have issues related to liver health, caution is advised when taking Prusent 2 Tablet. Please discuss your health history with your doctor before initiating this medicine.
Patients with severe renal impairment or end-stage renal disease should use Prusent 2 Tablet with caution. Consultation with your doctor is recommended before starting this medication.
Since Prusent 2 Tablet can cause fatigue or dizziness, especially during the initial days of treatment, be cautious while driving or operating machinery until you know how you react to the medicine.
Avoid taking Prusent 2 Tablet if you have known hypersensitivity to prucalopride or any of the excipients present in it.
Prusent 2 Tablet is not advised for use in children under 18 years of age due to lack of established safety and efficacy. Always consult your doctor before administering any medicine to a child.
Older patients should use Prusent 2 Tablet under medical supervision due to increased susceptibility to its side effects. If you are above 70 years of age, especially if you have liver or kidney issues or are on other medication, please consult your doctor before starting this medicine.
Serotonin Modulators: Medicines such as selective serotonin reuptake inhibitors (SSRIs) like fluoxetine, serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine, or monoamine oxidase inhibitors (MAOIs) like phenelzine may interact with Prusent 2 Tablet, potentially increasing the risk of serotonin syndrome.
Gastrointestinal Transit Time Modifiers: Medicines that slow down the movement of food and waste through your digestive system, like anticholinergics such as atropine and opioids like morphine, can reduce the effectiveness of Prusent 2 Tablet.
No specific food interactions with Prusent 2 Tablet have been reported. It can be taken with or without food.
Liver Diseases: People with severe liver impairment should use this medicine cautiously as its effects could be altered.
Psychiatric Conditions: If you have a history of depression, suicidal tendenc,ies or any other psychiatric illness, you should exercise caution when taking Prusent 2 Tablet.
Your doctor will prescribe the daily dose of Prusent 2 Tablet based on your specific needs. Factors such as your condition's severity and your response to treatment can influence this. It's crucial to stick to your prescribed dosage and never exceed it without consulting your doctor.
Taking more than the recommended dose of Prusent 2 Tablet may lead to symptoms like headache, nausea, or fatigue. If you've taken too much, keep calm and reach out to your doctor.
If you forget to take your Prusent 2 Tablet dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and resume your regular schedule. Always consult your doctor before making any changes to your dosage.
Store Prusent 2 Tablet in a cool, dry place.
The temperature should not exceed 30°C.
Protect the medicine from exposure to direct light and moisture.
Always keep this medicine out of sight and reach of children.
Use the medicine before the expiry date printed on the product label.
To manage constipation, include dietary fiber-rich foods like whole grains, fruits, and vegetables in your meals. This can aid regular bowel movements.
Regular physical activity can support intestinal motility. Try maintaining a consistent routine with moderate exercises such as walking or cycling.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Chronic Idiopathic Constipation |
| Drug Category | Serotonin 5-HT4 Agonist |
| Therapeutic Category | Gastrointestinal Prokinetic Agent |
Prusent 2 Tablet is used to manage chronic idiopathic constipation in adults, which means long-lasting constipation without any identifiable cause.
Prusent 2 Tablet works by increasing the movement and activity of the bowel, helping the stool move through the digestive tract more effectively.
Yes, Prusent 2 Tablet may be taken with or without food. It should be swallowed whole, not chewed or crushed, with a glass of water.
If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose; don't double up.
Common side effects can include headache, nausea, abdominal pain, diarrhoea, dizziness, fatigue, decreased appetite and flatulence. Usually these are mild and subside over time.
No, people with certain conditions like intestinal perforation or severe inflammatory conditions shouldn't use it. Also, its use is not recommended in pregnancy and lactation.
Limiting alcohol intake is advised as it can exacerbate side effects like dizziness. Always consult your doctor about such lifestyle choices when on medication.
Check out Editorial Policy
Shire. (2018). Highlights of prescribing information for motegrity [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210166s000lbl.pdf
Prucalopride: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a619011.html
DailyMed - MOTEGRITY- prucalopride tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bca1e4c6-4b2b-4876-8ab3-654629c4ff1b
Prucalopride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06480
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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