Osteofos 35 Tablet 4

Cipla Ltd.

Strip of 4 Units

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MRP ~~₹188.01~~

₹150.41

₹47/Units

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Composition

Alendronate / Alendronic Acid (35 Mg)

Strength:

35 MG 70 MG

Osteofos 35 Tablet is used to treat and prevent osteoporosis and Paget's disease of bone. It contains alendronate, a bisphosphonate that helps increase bone density and reduce the risk of fractures.

Apart from managing osteoporosis in postmenopausal women and men, this tablet is also used to manage glucocorticoid-induced osteoporosis and Paget's disease of the bone. These conditions can lead to pain, fractures, and other complications due to weakened bones.

It's crucial to take this medicine as directed by your doctor. Before starting this medicine, make sure you inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. To get the best results, continue taking the medicine for the duration prescribed by your doctor.

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Prevention and management of postmenopausal osteoporosis in women
Assisting with osteoporosis in men
Managing glucocorticoid-induced osteoporosis
Dealing with Paget's disease of bone

Swallow the tablet whole with a plain glass of water.
Do not chew or suck the tablet.
Always take the tablet on an empty stomach, at least 30 minutes before your first meal or other medication.
After taking the medicine, remain upright (sitting, standing or walking) for at least 30 minutes and until after your first meal.
Avoid taking this medicine at bedtime or before rising for the day.
For specific advice tailored to your needs, it's best to consult your doctor.

Osteofos 35 Tablet is taken orally.

Abdominal pain
Nausea
Vomiting
Constipation or diarrhoea
Flatulence
Headache
Dizziness or vertigo
Joint, muscle or bone pain
Acid regurgitation: This refers to the backflow of stomach acid into the oesophagus, causing heartburn.
Difficulty swallowing
Rash or itching

Managing the Side Effects:

Abdominal pain, nausea, vomiting, constipation, diarrhoea: Try taking your Osteofos 35 Tablet with food to minimise these gastrointestinal issues.
Acid regurgitation: If you have heartburn after taking this medication, consider taking it with a glass of water before meals.

Osteofos 35 Tablet consists of (alendronic acid 35 mg), which works as follows:

Binds to Bone Hydroxyapatite: Alendronic acid attaches itself to a compound in your bones called hydroxyapatite. This helps it focus its activity on areas where it's needed most.
Inhibits Osteoclasts: Alendronic acid works by blocking the activity of cells called osteoclasts. These cells break down bone tissue, so inhibiting them slows down bone loss.
Increases Bone Mass: With fewer osteoclasts breaking down bone tissue, there's an overall increase in bone mass. This leads to stronger bones less prone to fractures.

Pregnancy

Osteofos 35 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

If you are breastfeeding, consult your doctor to understand the potential risks and benefits of this medication.

Alcohol

There's no specific interaction of Osteofos 35 Tablet with alcohol. However, it's always a good idea to check with your doctor about potential interactions.

Liver

This medicine is often prescribed for older patients, who may be more susceptible to liver health issues. It is advisable to discuss liver-related concerns with your doctor before starting treatment with Osteofos 35 Tablet. They will evaluate if this medicine is suitable.

Kidney

Caution is advised before using Osteofos 35 Tablet if you have a history of any kidney problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

There are no known effects of Osteofos 35 Tablet on your ability to drive or operate machinery. However, if you experience side effects like dizziness or vertigo, it might be best to avoid such activities until you feel better.

Allergy

Avoid using Osteofos 35 Tablet if you have known hypersensitivity towards alendronic acid or any other component of the product. If you suspect an allergic reaction after taking this medicine, seek medical attention immediately.

Children

Osteofos 35 Tablet is not recommended for children under 18 years as safety and efficacy have not been established in this age group. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Osteofos 35 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Supplements: This medicine's absorption can be lessened by supplements containing calcium, magnesium, iron or aluminium, such as multivitamins and antacids. Make sure to take these at a different time of day.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Care should be taken when using NSAIDs like aspirin, ibuprofen, and naproxen with this medicine as they could increase the chance of gastrointestinal side effects.

Drug-Food Interactions

Foods rich in calcium, like milk or cheese, can decrease the absorption of this medicine. It's better to consume such foods at a different time of day.

Drug-Disease Interactions

Oesophagus problems: If you have oesophagal issues that slow down emptying, this medicine may not be suitable for you.
Hypocalcaemia: If your blood calcium levels are lower than normal, taking this medication might make it worse.
Dental issues: If you're planning on any dental surgery or procedures, you need to be cautious when using this medicine.

Daily Dose

Your doctor will prescribe the daily dose of Osteofos 35 Tablet based on your individual needs. It's crucial to adhere to the prescribed dosage and not to adjust it without your doctor's guidance.

Over Dose

If you accidentally take more than your prescribed dose of Osteofos 35 Tablet, you might experience symptoms like stomach upset, heartburn, or a drop in calcium levels in your blood. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take your regular dose of Osteofos 35 Tablet, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one and resume your usual schedule. Always consult your doctor before making any changes to your dosage.

Store Osteofos 35 Tablet at room temperature, ideally below 25°C.
Protect the medicine from moisture and light.
Keep it safely out of reach of children.
Always use this medicine before the expiry date printed on the pack.

Maintaining a balanced diet rich in calcium and vitamin D helps manage osteoporosis. Include dairy products, green leafy vegetables, and foods fortified with calcium and vitamin D in your daily meals.
Regular, low-impact exercises like walking, dancing or yoga can improve bone health and reduce the risk of fractures associated with osteoporosis.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Postmenopausal Osteoporosis, Male Osteoporosis, Paget's Disease
Drug Category	Osteoclast Inhibitor
Therapeutic Category	Bisphosphonate

What is Osteofos 35 Tablet used for?

Osteofos 35 Tablet is primarily used to manage osteoporosis and Paget's disease, conditions that weaken bones and may cause fractures.

How does Osteofos 35 Tablet work?

It contains alendronate which restricts the function of osteoclasts, the cells that break down bone, thereby increasing bone density.

How should I take Osteofos 35 Tablet?

Take it exactly as advised by your doctor.

Can I take this medicine with food or other medications?

No, avoid food, beverage or other medication for at least 30 minutes after taking Osteofos 35 Tablet to ensure proper absorption.

What are the common side effects of Osteofos 35 Tablet?

Common side effects include abdominal pain, nausea, vomiting, diarrhoea, constipation, flatulence, headache, dizziness, vertigo, muscle or bone pain.

Are there any precautions to be aware of before taking Osteofos 35 Tablet?

Avoid if you have oesophagus abnormalities, hypocalcemia or known hypersensitivity to any component of the product. Consult your doctor for other precautions.

What should I do if I miss a dose of Osteofos 35 Tablet?

If you miss a dose, take it the morning after remembering. Do not take two tablets on the same day. Resume your regular schedule.

Last Updated On 11 Aug. 2025 | 7:27AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

Expiry on or after: January 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Highlights of prescribing information. (2012). https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021575s017lbl.pdf
Merck Sharp & Dohme Corp. (1995). Highlights of prescribing information. In FOSAMAX. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020560s068,021575s024lbl.pdf
Mission Pharmacal Company. (1995). Highlights of prescribing information for Binosto [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/202344s011lbl.pdf
Parker, L. R. W., & Preuss, C. V. (2023, November 12). Alendronate. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK526073/
Alendronic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00630
Cummings, S. R., Santora, A. C., Black, D. M., & Russell, R. G. G. (2020). History of alendronate. Bone, 137, 115411. https://doi.org/10.1016/j.bone.2020.115411

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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