Strip of 10 Units
Old MRP ₹28.87
MRP ₹27.07
₹21.66
₹2.71/Units
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CompositionNapilex Cr 133/58 MG Tablet Cr 10 is used to manage epilepsy by reducing seizures. It belongs to the anticonvulsant class and can also help control manic episodes in bipolar disorder and prevent migraines. It stabilizes brain activity, preventing abnormal electrical discharges.
Consult your doctor for the correct dosage and inform them of any pre-existing conditions. If you experience side effects, notify your doctor. Continue the medication as prescribed to maintain its effectiveness.
Napilex Cr 133/58 MG Tablet Cr 10 is used for the following:
Controlling and managing epilepsy or seizures
Dealing with manic episodes in bipolar disorder
Prevention of migraine headaches
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet; it is a controlled-release formulation.
You can take this medicine with or without food, but taking it with food can help prevent stomach upset.
Always use this medicine as per your doctor's advice. Do not alter the dose without consulting your doctor first.
Napilex Cr 133/58 MG Tablet Cr 10 is taken orally.
Napilex Cr 133/58 MG Tablet Cr 10 might cause these common side effects:
Nausea
Vomiting
Diarrhoea
Abdominal pain
Anorexia: This is a loss of appetite, which might result in weight loss.
Dizziness
Tremors
Sedation: You might feel calm, relaxed, or sleepy.
Hair loss
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Napilex Cr 133/58 MG Tablet Cr 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here's how you can manage two common side effects:
Diarrhoea: Try taking Napilex Cr 133/58 MG Tablet Cr 10 with food to lessen this effect.
Nausea: If you feel sick after taking this medicine, consider taking it after meals.
Napilex Cr 133/58 MG Tablet Cr 10 contains sodium valproate/valproic acid (200 mg) which works on your body as follows:
Increases Brain Concentrations of GABA: Sodium valproate increases the levels of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter that helps calm down the excessive electrical nerve activity seen in epileptic seizures.
Potentiates GABA Activity: By inhibiting GABA degradation and increasing its synthesis and turnover, sodium valproate enhances the inhibitory activity of GABA.
Regulates Mood: For bipolar disorder management, sodium valproate may increase the activity of serotonin, a brain chemical known as a 'mood stabiliser'. Increased serotonin activity can help control mood swings associated with bipolar disorder.
Napilex Cr 133/58 MG Tablet Cr 10 can cause harm to the unborn baby, especially neural tube defects. If you are pregnant or planning to conceive, it is essential to consult your doctor before taking this medicine.
This medicine is found in breast milk and may affect your baby. Hence, breastfeeding while using Napilex Cr 133/58 MG Tablet Cr 10 is not recommended. Please consult with your doctor for the best advice.
Drinking alcohol while on this medication might intensify side effects like drowsiness and dizziness. If you regularly drink alcohol, please consult your doctor.
This medication is contraindicated for individuals with significant liver dysfunction or disease. If you have any liver issues, it is crucial to discuss them with your doctor before starting Napilex Cr 133/58 MG Tablet Cr 10.
If you have a history of kidney problems, caution is advised before starting this medicine. Consulting your doctor would be a wise decision.
Napilex Cr 133/58 MG Tablet Cr 10 may make you feel dizzy or drowsy. It would be prudent not to drive or operate heavy machinery until you know how this medication affects you. Consult your doctor before use.
If you're allergic to sodium valproate or any other ingredient in Napilex Cr 133/58 MG Tablet Cr 10, inform your doctor so that alternative medicine can be advised.
The safety and effectiveness of Napilex Cr 133/58 MG Tablet Cr 10 for migraine prophylaxis have not been established in children under 16 years of age. Always consult your doctor before giving any medicine to a child.
Lower starting doses are recommended for elderly patients due to decreased medication clearance and potential existing health conditions. Older patients should take Napilex Cr 133/58 MG Tablet Cr 10 under medical supervision.
Napilex Cr 133/58 MG Tablet Cr 10 interacts with the following medicines:
Anticonvulsants: Medicines such as phenytoin and carbamazepine may have their levels increased when taken alongside Napilex Cr 133/58 MG Tablet Cr 10.
CNS Depressants: This medicine may boost the effects of central nervous system depressants like alcohol, barbiturates, and benzodiazepines.
Salicylates: Medicines such as Aspirin can potentially increase the levels of valproate in your body.
Antibiotics: Certain antibiotics like carbapenems and rifampin might decrease valproate levels.
None
Napilex Cr 133/58 MG Tablet Cr 10 interacts with the following diseases:
Hepatic Disease: This medicine is contraindicated if you have liver disease or significant liver dysfunction.
Renal Impairment: If you have kidney problems, caution is advised due to potential alterations in drug clearance.
HIV Infection: Extra care should be taken if you have HIV infection as there could be possible interaction risks.
The daily dose of Napilex Cr 133/58 MG Tablet Cr 10 should be taken as directed by your doctor. The amount may vary depending on your specific needs and how well the medicine manages your symptoms. Don't change your dosage without consulting with your doctor first.
Taking more than the recommended dose of Napilex Cr 133/58 MG Tablet Cr 10 could lead to drowsiness or lethargy. If you've taken too much, let your doctor know right away to help avoid any potential complications.
If you forgot to take your Napilex Cr 133/58 MG Tablet Cr 10, take it as soon as you remember. If it's nearing time for your next dose, skip the one you missed and return to your normal schedule. Never double up on doses without consulting your doctor first.
Store Napilex Cr 133/58 MG Tablet Cr 10 at temperatures not exceeding 30°C.
Protect the medicine from moisture to maintain its effectiveness.
Keep it out of reach and sight of children for safety purposes.
Always check the expiry date on the pack before using the medicine.
If you're taking Napilex Cr 133/58 MG Tablet Cr 10 for epilepsy, avoiding alcohol is crucial as it can increase the risk of seizures.
For those using it to manage bipolar disorder, regular exercise can be beneficial as it helps improve your mood and reduce stress.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Epilepsy, Bipolar disorder, Migraine prevention |
| Drug Category | Anticonvulsant, Mood-stabilizer |
| Therapeutic Category | Antiepileptic |
Napilex Cr 133/58 MG Tablet Cr 10 is used to manage epilepsy, bipolar disorder, and prevent migraine headaches. Always take it as directed by your doctor.
This medicine works by increasing certain chemicals in the brain that help reduce seizure activity and stabilise mood.
Yes, Napilex Cr 133/58 MG Tablet Cr 10 can be taken with or without food. However, taking it with food may help reduce stomach upset. Please consult with your doctor for the best advice.
Certain medications containing ingredients such as Alprazolam and Aripiprazole may interact with Napilex Cr 133/58 MG Tablet Cr 10. Always inform your doctor about all the medicines you're currently taking.
If you miss a dose, take it as soon as you remember. If it's close to your next dose time, skip the missed dose - don't double up. Never adjust your dosage without consulting your doctor.
Napilex Cr 133/58 MG Tablet Cr 10 may cause dizziness or drowsiness. Don't drive or operate machinery until you know how this medicine affects you. Consult your doctor before use.
Avoid alcohol as it can worsen side effects like drowsiness and dizziness. Also, don't start new medications without informing your doctor. Consult your doctor for individualized directions and advice.
Check out Editorial Policy
Rahman, M., Awosika, A. O., & Nguyen, H. (2024, March 19). Valproic acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559112/
National Health Service (NHS). (n.d.). Valproic acid: medicine to treat epilepsy and bipolar disorder. Retrieved April 1, 2024, from https://www.nhs.uk/medicines/valproic-acid/
U.S. Food and Drug Administration (FDA). (n.d.). Depakene (valproic acid) capsules and oral solution. Retrieved April 1, 2024, from https://www.fda.gov/media/71502/download
Valproic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00313
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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