Monotrate 20 Tablet 10

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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MRP ~~₹44.5~~

₹35.6

₹4.45/Units

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Composition

Isosorbide-5-mononitrate / Isosorbide Mononitrate (20 Mg)

Strength:

20 MG 40 MG 10 MG

Monotrate 20 Tablet is used to manage chest pain (angina) and improve heart function. It works by relaxing blood vessels, improving blood flow, and reducing the heart’s workload. It belongs to the class of drugs known as nitrate vasodilators.

Before using the Monotrate 20 Tablet, inform your doctor about any history of liver or kidney diseases, glaucoma, thyroid issues, or if you have experienced low body temperature. This information is essential for your doctor to consider for safe and effective treatment.

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The Monotrate 20 Tablet is used for the prevention and treatment of:

Angina pectoris (chest pain)

When taking the medication, swallow the tablet without crushing or breaking it.
You have the flexibility to take it with or without food, but for optimal results, it's recommended to take it at the same time every day.

Monotrate 20 Tablet is taken orally.

Common side effects of Monotrate 20 Tablet include:

Dizziness
Nausea
Decreased blood pressure (hypotension)
Headache
Tiredness
Rapid heartbeat

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing Monotrate 20 Tablet. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

The Monotrate 20 Tablet contains the following component:

Isosorbide mononitrate (20 mg): It is a nitrate vasodilator that works by dilating the blood vessels, improving blood flow, and reducing the pressure on the heart. This helps to reduce the chest pain associated with angina and may also reduce the frequency and severity of angina attacks.

Pregnancy

If you are pregnant or planning to become pregnant, inform your doctor before starting Monotrate 20 Tablet. The use of Monotrate 20 Tablet during pregnancy should only be done if needed and prescribed by a doctor.

Breastfeeding

Consult your doctor before taking Monotrate 20 Tablet while breastfeeding. The medication may cross into breast milk, and its safety during breastfeeding is not well-established.

Alcohol

Avoid consuming alcohol while on Monotrate 20 as it may increase the risk of side effects such as dizziness and low blood pressure.

Liver

Individuals with liver problems should exercise caution while taking the Monotrate 20 Tablet. Your doctor may adjust the regimen based on your liver function.

Kidney

If you have kidney issues, inform your doctor before using Monotrate 20 Tablet. Dosing adjustments may be necessary based on your kidney function.

Using Machines & Driving

The use of Monotrate 20 Tablet can cause dizziness or fainting. Be cautious while driving or heavy work until you know how the medication affects you.

Allergy

If you are allergic to any of the components in Monotrate 20 Tablet, avoid using it. If you experience allergic reactions like rash, itching, or swelling, seek medical attention immediately. Read the label carefully before taking this medicine.

Children

The safety and effectiveness of the Monotrate 20 Tablet in children have not been established, so it should only be used in children if prescribed by a doctor.

Older Patients

Older patients may be more sensitive to the adverse effects of the Monotrate 20 Tablet. Dosing adjustments may be necessary for elderly individuals to avoid adverse reactions.

Drug-Drug Interactions

The Montrate 20 Tablet can interact with the following medications, including:

Phosphodiesterase-5 inhibitors, like sildenafil, tadalafil, and vardenafil, can cause severe hypotension, syncope, or myocardial ischemia when taken concomitantly with Monotrate 20 Tablet.
Medicines used to treat heart failure, such as riociguat can cause the risk of hypotension when taken along with this medication.
Calcium channel blockers such as amlodipine can cause orthostatic hypotension when taken along with this medication.

Drug-Disease Interactions

Monotrate 20 Tablet can interact with the following conditions/diseases:

Anaemia (low red blood cell count): The Monotrate 20 Tablet can cause complications in the anaemia.
Hypotension (low blood pressure): The Monotrate 20 Tablet can decrease blood pressure further.
Liver disease: The Monotrate 20 Tablet can further worsen this condition.
Kidney failure (dialysis): The Monotrate 20 Tablet can further worsen this condition.

Daily Dose

The daily dose of Monotrate 20 Tablet should be taken as your doctor prescribes. The dosage may change based on individual factors such as age, severity of the condition, and response to treatment.

Over Dose

Taking more than the recommended dosage of Monotrate 20 Tablet can result in unwanted side effects such as pulsating/throbbing headache, reddening of the skin, increased temperature, blurred vision, rapid drop in blood pressure, and fainting. If you suspect an overdose, it is vital to seek immediate medical help to prevent any potential harm.

Missed Dose

If you forget a dose of Monotrate 20 Tablet, take it as soon as you remember. However, avoid repeating the dose.

The storage instructions for Monotrate 20 Tablet are as follows:

Monotrate 20 Tablet should be stored at room temperature, under 30°C.
Please protect it from light and moisture.
Keep the tablets away from children and pets.
Do not use this medicine after the expiry date has passed.

Include abundant fruits, vegetables, whole grains, and low-fat protein sources like nuts and fish.
Engage in regular physical activities to promote heart health.
Maintain a healthy weight and manage diabetes effectively.
Quit smoking to protect your heart and overall well-being.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Angina (chest pain)
Drug Category	Nitrate vasodilators
Therapeutic Category	Cardiac

Does Monotrate 20 Tablet decrease heart rate?

Yes, Monotrate 20 Tablet can decrease heart rate as it helps reduce the workload on the heart.

What is the composition of the Monotrate 20 Tablet?

Monotrate 20 Tablet contains the active ingredient isosorbide mononitrate, which belongs to the class of medications known as nitrate vasodilators.

Is Monotrate 20 Tablet blood thinner?

No, Monotrate 20 Tablet is not a blood thinner. It treats angina (chest pain) by relaxing and widening blood vessels and, therefore, improving blood flow to the heart.

Does Monotrate 20 Tablet affect BP?

Yes, the use of Monotrate 20 Tablet can affect blood pressure. It helps lower blood pressure by dilating the blood vessels, leading to easy blood flow.

What does Monotrate 20 Tablet do for the heart?

Monotrate 20 Tablet helps manage angina by reducing the heart's workload and improving blood flow to the heart muscle, which helps relieve chest pain and reduce the risk of heart-related complications.

When is the best time to take the Monotrate 20 Tablet?

The best time to take Monotrate 20 Tablet is as your doctor prescribes. It is usually taken on an empty stomach in the morning to maintain consistent blood levels throughout the day.

How long is the effect of the Monotrate 20 Tablet?

The effect of Monotrate 20 Tablet may vary depending on the dosage and individual response. Extended-release formulations are designed to provide a continuous effect over 12 to 24 hours.

Is Monotrate 20 Tablet a beta blocker?

No, Monotrate 20 Tablet is not a beta blocker. It is a nitrate vasodilator medication used to treat angina by dilating blood vessels.

Can Monotrate 20 Tablet be given twice daily?

The dosing frequency of Monotrate 20 Tablet depends on the individual's condition and the formulation prescribed by the doctor. Some formulations may require twice-daily dosing, while others are taken once a day.

Does Monotrate 20 Tablet cause back pain?

Back pain is not a common side effect of Monotrate 20. However, if you experience any unusual or severe side effects while taking Monotrate 20, it is essential to consult your doctor.

Is Monotrate 20 Tablet nitroglycerin?

Monotrate 20 Tablet contains isosorbide mononitrate, which is closely related to nitroglycerin. Both are nitrates used to treat angina, but they differ in how they are absorbed and metabolised in the body.

Can you take Monotrate 20 Tablet long-term?

Your doctor determines the duration of Monotrate 20 Tablet treatment based on your medical condition. In some cases, Monotrate 20 Tablet may be prescribed for long-term use to manage chronic conditions like angina. It is critical to follow your doctor's instructions concerning the duration of treatment.

Last Updated On 29 Jul. 2025 | 11:37AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead & Reviewer | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

Expiry on or after: November 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

1. (isosorbide mononitrate, USP) Rx only - food and drug administration. (n.d.-d). https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020215s024lbl.pdf

2. Center for Drug Evaluation and Research. (n.d.). DRUGS@FDA data files. U.S. Food and Drug Administration. https://www.fda.gov/drugs/drug-approvals-and-databases/drugsfda-data-files

3. Isosorbide mononitrate tablets 10 MG - patient information leaflet (PIL) - (EMC). (n.d.). https://www.medicines.org.uk/emc/product/2697/pil#gref

4. NHS. (n.d.). NHS choices. https://www.nhs.uk/medicines/isosorbide-mononitrate-dinitrate/

5. KD. Tripathi. Antianginal and Other Anti-ischaemic Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page 539-588

6. McDermott Laboratories Limited trading as Gerard Laboratories. Health Products Regulatory Authority (HPRA). Available from: https://www.hpra.ie/img/uploaded/swedocuments/eaf73f71-5d63-415f-be5e-d37e58d92ccf.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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