Metrotrex 15 Tablet 10

Steris Healthcare

Strip of 10 Units

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Old MRP ₹155

MRP ~~₹145.31~~

₹72.51

₹14.53/Units

50.1% off

*MRP inclusive of all taxes

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Prescription required for this medicine

Store Below 30^o C

Composition

Methotrexate (15 Mg)

Strength:

5 MG 7.5 MG 10 MG 15 MG 2.5 MG

Metrotrex 15 Tablet 10 is used for managing severe rheumatoid arthritis, a chronic autoimmune condition that causes joint inflammation. It is also used to treat psoriasis and other inflammatory conditions. This tablet helps slow the proliferation of skin cells and reduce inflammation in joints, improving symptoms and quality of life.

Before starting this medicine, consult your doctor about your medical history, ongoing treatments, and other medications. Follow your doctor’s prescribed dosage and continue taking the medicine for optimal results.

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Metrotrex 15 Tablet 10 is used for managing severe rheumatoid arthritis, reducing symptoms of severe psoriasis, and controlling certain types of cancer, such as breast and lung cancer. It also reduces cell growth in severe leukaemia and advanced non-Hodgkin's lymphoma, and controls severe psoriatic arthritis and ankylosing spondylitis.

Take Metrotrex 15 Tablet 10 as advised below:

Swallow the tablet whole with water. Don't crush or chew it.
Follow your doctor's directions about dosage and duration carefully. Remember, exceeding the recommended dose can have adverse effects.

Metrotrex 15 Tablet 10 can be taken orally.

Metrotrex 15 Tablet 10 may cause diarrhoea, hair loss, skin rash, liver function abnormalities, and mucositis (inflammation and soreness of the mucous membranes).

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Metrotrex 15 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Diarrhoea: Try to ensure that you stay hydrated by drinking plenty of fluids throughout the day.
Hair loss: You might consider using a gentle, mild shampoo and avoiding heat styling to reduce further damage to your hair.

Metrotrex 15 Tablet 10 contains methotrexate (15 mg), which works on the body as follows:

Antimetabolite activity: Methotrexate functions as an antimetabolite, meaning it interferes with cellular metabolism. In simple terms, it disrupts the normal functioning of cells.
Folic acid antagonist: As a folic acid antagonist, methotrexate inhibits an enzyme crucial for the synthesis of folic acid in your body. Folic acid is needed for cell growth and division.
Inhibits inflammation: By inhibiting certain enzymes, methotrexate reduces inflammation in your body. This helps manage symptoms in inflammatory conditions like rheumatoid arthritis and psoriasis.

Pregnancy

Metrotrex 15 Tablet 10 is strictly contraindicated during pregnancy. It poses risks to foetal development and should not be used during pregnancy unless specifically prescribed by a specialist.

Breastfeeding

This medication is also not recommended for breastfeeding mothers, as its components can pass into breast milk and may adversely affect the infant. Consult your doctor to discuss alternatives or to weigh the potential risks and benefits before using this medicine if you are breastfeeding.

Alcohol

Combining Metrotrex 15 Tablet 10 with alcohol can exacerbate side effects, especially those affecting the liver. It is advisable to avoid alcohol entirely or consult your doctor regarding alcohol intake while on this medication.

Liver

Metrotrex 15 Tablet 10 may affect liver function, particularly in individuals with pre-existing liver conditions. If you have a history of liver issues, it’s crucial to inform your doctor. Your doctor may suggest periodic liver function tests and adjust the dosage to minimise potential complications.

Kidney

If you have a history of kidney disease, it’s essential to exercise caution with Metrotrex 15 Tablet 10, as it can impact kidney function. Make sure to inform your doctor about any kidney-related health issues before beginning treatment.

Using Machines & Driving

Metrotrex 15 Tablet 10 may cause side effects such as dizziness, fatigue, or drowsiness, which can impair your ability to drive or operate machinery. If you experience these symptoms, take extra care and avoid activities that require mental alertness until you know how the medication affects you.

Allergy

If you're allergic to methotrexate or any other component of Metrotrex 15 Tablet 10, this medication should be avoided. Your doctor can help determine whether this medicine is suitable for you based on your allergy history.

Children

Metrotrex 15 Tablet 10 is not intended for use in children under 18 years.

Older Patients

Older patients should take Metrotrex 15 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised, especially if patients are above 70 years of age. Your doctor can guide you based on your health status.

Drug-Drug Interactions

Metrotrex 15 Tablet 10 interacts with the following medicines:

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Medicines such as ibuprofen and naproxen can interact with this tablet, potentially increasing the risk of side effects like liver damage.
Immunosuppressants: When taken with this tablet, medicines like cyclosporine can increase the toxicity levels in the body.
Antibiotics: Certain types of antibiotics, like tetracycline, may interact adversely with this tablet, potentially leading to increased side effects.

Drug-Food Interactions

Certain foods may interact with Metrotrex 15 Tablet 10.

High protein foods: Foods rich in protein might affect the absorption of methotrexate from the stomach, impacting its efficacy.

Drug-Disease Interactions

Metrotrex 15 Tablet 10 interacts with the following diseases:

Liver disease: People with liver disease should be cautious as this tablet could potentially exacerbate their condition.
Kidney disease: The medicine could have an adverse effect on patients suffering from kidney disease, as it may further impair kidney function.
Blood disorders: Patients with blood disorders need to exercise caution while using this medication, as it could potentially decrease white blood cells and platelets.

Daily Dose

The dose of this injection should be administered as recommended by your doctor. The dosage may vary based on individual factors, such as the severity of the condition and response to treatment. It is usually administered once weekly.

Over Dose

Overdosing of Metrotrex 15 Tablet 10 is less likely to occur as it is administered by a healthcare professional. In case of accidental overdose, symptoms such as severe bone marrow suppression, gastrointestinal bleeding, liver damage, and pneumonitis can occur.

Missed Dose

If you have forgotten to take your Metrotrex 15 Tablet 10 as scheduled, take it as soon as you remember. However, if your next dose is due soon, skip the missed one and continue with your regular dosage schedule. Don't increase your dosage without consulting your doctor.

Store Metrotrex 15 Tablet 10 in a cool place.
Keep it away from direct sunlight and damp areas like the bathroom or kitchen.
Ensure it's stored out of the reach and sight of children.
Make sure to use this medicine before its expiry date

Since this tablet is typically used to manage conditions like rheumatoid arthritis, embrace a balanced diet rich in omega-3 fatty acids. Foods like fish, walnuts and flaxseeds can reduce inflammation.
Regular exercise improves joint flexibility. However, switch to gentle activities like swimming or yoga during flare-ups to avoid straining your joints. Always consult your doctor before starting any new exercise regime.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Rheumatoid Arthritis, Psoriasis
Drug Category	Anti-metabolite
Therapeutic Category	Anti-rheumatic

What is Metrotrex 15 Tablet 10 used for?

This tablet is commonly prescribed for managing rheumatoid arthritis and certain types of cancers. It works by reducing the growth of abnormal cells and moderating immune activity, making it effective in autoimmune conditions and cancer treatment.

Can I drink alcohol while using Metrotrex 15 Tablet 10?

It’s advised to avoid alcohol while taking this tablet, as alcohol can increase the risk of liver damage and intensify side effects. Discuss any alcohol consumption with your doctor before beginning treatment.

Can I use this medicine during pregnancy or breastfeeding?

No, this tablet should not be used during pregnancy or breastfeeding, as it can pose risks to both foetal development and breastfeeding infants. Consult your doctor for alternative options if you are pregnant, planning a pregnancy, or breastfeeding.

What are the potential side effects of Metrotrex 15 Tablet 10?

Possible side effects of this tablet include nausea, vomiting, fatigue, appetite loss, mouth sores, and diarrhoea. Consult your doctor if these symptoms persist or worsen, as adjustments may be necessary.

Does this medicine interact with other medicines or food?

Yes,this tablet can interact with other medications and foods. Always inform your doctor of any other medications you are taking to avoid potential interactions that could affect the medication’s effectiveness.

How should I store Metrotrex 15 Tablet 10?

Store it in a cool and dry place, away from sunlight and out of reach of children. Do not freeze the tablet.

Last Updated On 30 Dec. 2025 | 6:11AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 9 years

PhD in Chemistry

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

Tanaji Chowk, Ambedkar Nagar, Kurla West, Kurla, Mumbai, Maharashtra 400070

Country of origin: INDIA

Expiry on or after: May 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

METHOTREXATE TABLETS. (N.d.). Fda.Gov. Retrieved November 9, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/008085s066lbl.pdf
Methotrexate. (n.d.). Medlineplus.Gov. Retrieved November 9, 2024, from https://medlineplus.gov/druginfo/meds/a682019.html
Hanoodi, M., & Mittal, M. (2024). Methotrexate. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK556114/
Methotrexate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00563

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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