Methora 15 Tablet 4

Hetero Healthcare Ltd

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Composition

Methotrexate (15 Mg)

Strength:

7.5 MG 15 MG 10 MG

Methora 15 Tablet 4 is primarily prescribed to manage severe rheumatoid arthritis, a chronic autoimmune condition that causes painful inflammation and damage to the joints. It belongs to the group of medicines classified as an antimetabolite.
Beyond rheumatoid arthritis, this tablet is also indicated for treating psoriasis, a skin condition marked by red, scaly patches that can be painful and lead to excessive skin cell growth. By slowing down the proliferation of these cells, this medicine helps improve the symptoms and appearance of the skin in psoriasis patients.
Before starting this medicine, consult your doctor who will determine the appropriate dosage and frequency. Make sure you inform your doctor about any pre-existing conditions or ongoing medication. If you notice any side effects while on this medicine, notify your doctor immediately. It's important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Methora 15 Tablet 4 is used for the following:

Management of severe rheumatoid arthritis in adults
Reducing symptoms of severe psoriasis in adults
Controlling symptoms of certain types of cancer, such as breast and lung cancer
Reducing the growth of certain cells in adults with severe leukaemia
Managing advanced stages of non-Hodgkin's lymphoma in adults
Control of severe or disabling psoriatic arthritis in adults
Helping to reduce symptoms in adults with severe ankylosing spondylitis.

Take Methora 15 Tablet 4 as advised below:

Swallow the tablet whole with water. Don't crush or chew it.
Follow your doctor's directions about dosage and duration carefully. Remember, exceeding the recommended dose can have adverse effects.

Methora 15 Tablet 4 can be taken orally.

Methora 15 Tablet 4 may cause the following side effects:

Diarrhoea
Hair loss
Skin rash
Liver function abnormality
Mucositis (Inflammation and soreness of the mucous membranes - the soft tissues lining your digestive tract)

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Methora 15 Tablet 4. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Diarrhoea: Try to ensure that you stay hydrated by drinking plenty of fluids throughout the day.
Hair loss: You might consider using a gentle, mild shampoo and avoiding heat styling to reduce further damage to your hair.

Methora 15 Tablet 4 contains methotrexate (15 mg), which works on the body as follows:

Antimetabolite activity: Methotrexate functions as an antimetabolite, meaning it interferes with cellular metabolism. In simple terms, it disrupts the normal functioning of cells.
Folic acid antagonist: As a folic acid antagonist, methotrexate inhibits an enzyme crucial for the synthesis of folic acid in your body. Folic acid is needed for cell growth and division.
Inhibits inflammation: By inhibiting certain enzymes, methotrexate reduces inflammation in your body. This helps manage symptoms in inflammatory conditions like rheumatoid arthritis and psoriasis.

Pregnancy

Methora 15 Tablet 4 is strictly contraindicated during pregnancy. It poses risks to foetal development and should not be used during pregnancy unless specifically prescribed by a specialist.

Breastfeeding

This medication is also not recommended for breastfeeding mothers, as its components can pass into breast milk and may adversely affect the infant. Consult your doctor to discuss alternatives or to weigh the potential risks and benefits before using this medicine if you are breastfeeding.

Alcohol

Combining Methora 15 Tablet 4 with alcohol can exacerbate side effects, especially those affecting the liver. It is advisable to avoid alcohol entirely or consult your doctor regarding alcohol intake while on this medication.

Liver

Methora 15 Tablet 4 may affect liver function, particularly in individuals with pre-existing liver conditions. If you have a history of liver issues, it’s crucial to inform your doctor. Your doctor may suggest periodic liver function tests and adjust the dosage to minimise potential complications.

Kidney

If you have a history of kidney disease, it’s essential to exercise caution with Methora 15 Tablet 4, as it can impact kidney function. Make sure to inform your doctor about any kidney-related health issues before beginning treatment.

Using Machines & Driving

Methora 15 Tablet 4 may cause side effects such as dizziness, fatigue, or drowsiness, which can impair your ability to drive or operate machinery. If you experience these symptoms, take extra care and avoid activities that require mental alertness until you know how the medication affects you.

Allergy

If you're allergic to methotrexate or any other component of Methora 15 Tablet 4, this medication should be avoided. Your doctor can help determine whether this medicine is suitable for you based on your allergy history.

Children

Methora 15 Tablet 4 is not intended for use in children under 18 years.

Older Patients

Older patients should take Methora 15 Tablet 4 under medical supervision as they may be more susceptible to its side effects. Caution is advised, especially if patients are above 70 years of age. Your doctor can guide you based on your health status.

Drug-Drug Interactions

Methora 15 Tablet 4 interacts with the following medicines:

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Medicines such as ibuprofen and naproxen can interact with this tablet, potentially increasing the risk of side effects like liver damage.
Immunosuppressants: When taken with this tablet, medicines like cyclosporine can increase the toxicity levels in the body.
Antibiotics: Certain types of antibiotics, like tetracycline, may interact adversely with this tablet, potentially leading to increased side effects.

Drug-Food Interactions

Certain foods may interact with Methora 15 Tablet 4.

High protein foods: Foods rich in protein might affect the absorption of methotrexate from the stomach, impacting its efficacy.

Drug-Disease Interactions

Methora 15 Tablet 4 interacts with the following diseases:

Liver disease: People with liver disease should be cautious as this tablet could potentially exacerbate their condition.
Kidney disease: The medicine could have an adverse effect on patients suffering from kidney disease, as it may further impair kidney function.
Blood disorders: Patients with blood disorders need to exercise caution while using this medication, as it could potentially decrease white blood cells and platelets.

Daily Dose

The dose of this injection should be administered as recommended by your doctor. The dosage may vary based on individual factors, such as the severity of the condition and response to treatment. It is usually administered once weekly.

Over Dose

Overdosing of Methora 15 Tablet 4 is less likely to occur as it is administered by a healthcare professional. In case of accidental overdose, symptoms such as severe bone marrow suppression, gastrointestinal bleeding, liver damage, and pneumonitis can occur.

Missed Dose

If you have forgotten to take your Methora 15 Tablet 4 as scheduled, take it as soon as you remember. However, if your next dose is due soon, skip the missed one and continue with your regular dosage schedule. Don't increase your dosage without consulting your doctor.

Store Methora 15 Tablet 4 in a cool place.
Keep it away from direct sunlight and damp areas like the bathroom or kitchen.
Ensure it's stored out of the reach and sight of children.
Make sure to use this medicine before its expiry date

Since this tablet is typically used to manage conditions like rheumatoid arthritis, embrace a balanced diet rich in omega-3 fatty acids. Foods like fish, walnuts and flaxseeds can reduce inflammation.
Regular exercise improves joint flexibility. However, switch to gentle activities like swimming or yoga during flare-ups to avoid straining your joints. Always consult your doctor before starting any new exercise regime.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Rheumatoid Arthritis, Psoriasis
Drug Category	Anti-metabolite
Therapeutic Category	Anti-rheumatic

What is Methora 15 Tablet 4 used for?

This tablet is commonly prescribed for managing rheumatoid arthritis and certain types of cancers. It works by reducing the growth of abnormal cells and moderating immune activity, making it effective in autoimmune conditions and cancer treatment.

Can I drink alcohol while using Methora 15 Tablet 4?

It’s advised to avoid alcohol while taking this tablet, as alcohol can increase the risk of liver damage and intensify side effects. Discuss any alcohol consumption with your doctor before beginning treatment.

Can I use this medicine during pregnancy or breastfeeding?

No, this tablet should not be used during pregnancy or breastfeeding, as it can pose risks to both foetal development and breastfeeding infants. Consult your doctor for alternative options if you are pregnant, planning a pregnancy, or breastfeeding.

What are the potential side effects of Methora 15 Tablet 4?

Possible side effects of this tablet include nausea, vomiting, fatigue, appetite loss, mouth sores, and diarrhoea. Consult your doctor if these symptoms persist or worsen, as adjustments may be necessary.

Does this medicine interact with other medicines or food?

Yes,this tablet can interact with other medications and foods. Always inform your doctor of any other medications you are taking to avoid potential interactions that could affect the medication’s effectiveness.

How should I store Methora 15 Tablet 4?

Store it in a cool and dry place, away from sunlight and out of reach of children. Do not freeze the tablet.

Last Updated On 21 Aug. 2025 | 9:57AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 9 years

PhD in Chemistry

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

A-201/202/B-201, Dipti Classic, 32/34, W.T. Suren Rd, Andheri East, Mumbai, Maharashtra 400093

Country of origin: INDIA

Expiry on or after: January 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

METHOTREXATE TABLETS. (N.d.). Fda.Gov. Retrieved November 9, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/008085s066lbl.pdf
Methotrexate. (n.d.). Medlineplus.Gov. Retrieved November 9, 2024, from https://medlineplus.gov/druginfo/meds/a682019.html
Hanoodi, M., & Mittal, M. (2024). Methotrexate. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK556114/
Methotrexate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00563

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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