Megacholin Plus Tablet 10

Aristo Pharmaceuticals Pvt.ltd

Strip of 10 Units

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MRP ~~₹612~~

₹489.6

₹61.2/Units

20% off

*MRP inclusive of all taxes

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15 days Easy returns

Prescription required for this medicine

Store Below 30° C

Composition

Citicoline (500 Mg) + Piracetam (800 Mg)

Megacholin Plus Tablet is used as an adjunct in the management of acute stroke to help support neurological recovery. It is used alongside standard stroke treatment and rehabilitation.

It contains citicoline and piracetam, two medicines used to support brain cell health and function. Take it as prescribed by your doctor, with or after food if it causes stomach upset. Follow the full course as directed.

Rest, appropriate rehabilitation, and physiotherapy or speech therapy as recommended by your doctor or care team all support recovery alongside this medicine. Controlling blood pressure and blood sugar helps protect against further events.

Before taking this medicine, tell your doctor about any kidney problems, liver conditions, bleeding disorders, or epilepsy, and about all other medicines you take. Report any unusual mental changes. Speak to your doctor before use if you are pregnant or breastfeeding.

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Megacholin Plus Tablet is used in adults as an adjunct in the management of acute stroke to support neurological recovery.

Uses of Megacholin Plus Tablet are:

Acute Stroke: Used as an adjunct in the management of stroke.
Neurological Recovery: Helps support recovery following a stroke.

When using Megacholin Plus Tablet, ensure you follow these steps:

Swallow the tablet whole, with a glass of water.
Avoid crushing or chewing the tablet.
The medicine can be taken with or without food.
Do not exceed the prescribed dose without consulting your doctor.
Always consult your doctor before stopping this medicine.

Megacholin Plus Tablet is taken orally.

Megacholin Plus Tablet may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Megacholin Plus Tablet:

Neurological: Headache, agitation, and difficulty sleeping (insomnia).
Digestive: Feeling sick (nausea) and loose motions (diarrhoea). Taking it with food may help.
General: Weight gain.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Megacholin Plus Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Megacholin Plus Tablet with food or milk.
Insomnia: Consider taking this medicine in the morning to avoid sleep disturbances at night.

Megacholin Plus Tablet has two active ingredients:

Citicoline (500 mg): This neuroprotective agent stabilises cell membranes and reduces oxidative stress on cells. It boosts synthesis of phosphatidylcholine, a key component of cell membranes, which aids in neuron communication.
Piracetam (800 mg): As a nootropic, piracetam enhances neuroplasticity and improves blood microcirculation in the brain. It also optimises neuronal oxygen consumption and regulates neurotransmitter systems.

Pregnancy

Megacholin Plus Tablet should be used with caution during pregnancy. It's wise to discuss this with your doctor before starting this medicine.

Breastfeeding

Breastfeeding women should take Megacholin Plus Tablet with caution. It's best to consult your doctor to understand the potential risks and benefits.

Alcohol

There is no known interaction between alcohol and Megacholin Plus Tablet. However, alcohol consumption can affect your general health and may delay recovery from a stroke.

Liver

Caution is advised while taking Megacholin Plus Tablet if you have mild to moderate liver impairment. If you are experiencing liver problems, discuss them with your doctor before starting this medicine.

Kidney

If you have any kidney problems, it's advisable to talk to your doctor before taking Megacholin Plus Tablet.

Use In Driving And Operating Machinery

Megacholin Plus Tablet may cause dizziness or drowsiness. Avoid driving or operating machinery until you are sure about how it affects you.

Allergy

If you're allergic to citicoline, piracetam or any other components of Megacholin Plus Tablet, avoid using it.

Children

Megacholin Plus Tablet is not recommended for children under 18 years of age. Always consult your doctor before giving it to a child.

Older Patients

Older patients should take Megacholin Plus Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Megacholin Plus Tablet interacts with the following medicines:

Blood Thinners: This medicine may increase the risk of bleeding when taken with anticoagulants or antiplatelets like aspirin, clopidogrel and warfarin.
Central Nervous System (CNS) Depressants: When taken with CNS depressants such as diazepam, alprazolam, and lorazepam, this medicine could increase their sedative effects.
Thyroid Medicines: The effectiveness of thyroid hormones like levothyroxine may be reduced when used alongside Megacholin Plus Tablet.
Antiepileptic Medicines: The efficacy of antiepileptic medicines such as carbamazepine, phenytoin, and valproic acid might be decreased due to interaction.

Drug-Food Interactions

Megacholin Plus Tablet does not have any known interactions with food items.

Drug-Disease Interactions

Megacholin Plus Tablet interacts with the following diseases:

Bleeding Disorders: In patients with disorders that increase bleeding, this medicine might enhance the risk of haemorrhage.
Kidney Disease: For those suffering from severe renal impairment, Megacholin Plus Tablet usage needs caution due to potential excessive medicine accumulation.
Liver Disease: In individuals with severe liver disease, caution is advised due to potential altered medicine metabolism and clearance.

Daily Dose

Your doctor will prescribe the daily dose of Megacholin Plus Tablet for you. This will depend on various factors such as how severe your condition is and how you respond to the medicine. Ensure you stick to the dosage suggested by your doctor and don't alter it without consulting them first.

Over Dose

If you accidentally take more Megacholin Plus Tablets than prescribed, you might feel agitated, confused, or unusually restless. You might also experience tremors or excessive sleepiness. If these symptoms occur, reach out to your doctor.

Missed Dose

If you forget to take your Megacholin Plus Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and continue with your usual schedule. Don't increase the dose without consulting your doctor.

Store the Megacholin Plus Tablet in a cool, dry place.
The ideal temperature for storage is below 30 degrees Celsius.
Protect the medicine from light and moisture.
Keep this medicine out of reach of children.
Always check the expiry date before taking the tablet.

Include foods rich in omega-3 fatty acids in your diet. These healthy fats, found in fish and walnuts, support brain health and could help manage stroke recovery.
Regular physical activity can aid recovery after a stroke. Start with gentle exercises and gradually increase intensity as you build strength, always under your doctor's guidance.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Acute Stroke
Drug Category	Neuroprotective, Nootropic
Therapeutic Category	Stroke Management

What Is Megacholin Plus Tablet Used For?

Megacholin Plus Tablet is used to manage acute stroke. It helps speed up recovery, reduce brain damage, and promote healing.

How Does Megacholin Plus Tablet Work?

This medicine works by protecting and repairing damaged brain cells. It stabilises cell membranes, reduces oxidative stress, and enhances communication between neurons.

Can I Take Megacholin Plus Tablet with Food?

Yes, you can take Megacholin Plus Tablet with or without food. Always follow your doctor's instructions for taking this medicine.

Are There Any Side Effects of Megacholin Plus Tablet?

Some common side effects include headache, nausea, diarrhoea, agitation, insomnia, and weight gain. If these persist or worsen, consult your doctor.

Who Should Not Take Megacholin Plus Tablet?

Those with hypersensitivity to citicoline or piracetam should not take this medicine. Also, use with caution if you're pregnant, breastfeeding or have severe renal impairment.

Can I Drive After Taking Megacholin Plus Tablet?

This medicine may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how it affects you.

What Should I Do In Case of an Overdose?

In case of an overdose, symptoms include agitation and confusion. Contact a poison control centre or emergency services immediately.

Last Updated On 22 Jul. 2026 | 11:38AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 10 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

23 A, Shah Industrial Estate, Off Veera Desai Rd, Andheri West, Mumbai, Maharashtra 400053

Country of origin: INDIA

Expiry on or after: December 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. Food and Drug Administration. (2012). Nootropil (piracetam) Tablets: U.S. Prescribing Information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203155s000lbl.pdf
U.S. Food and Drug Administration. (2015). CerAxon (citicoline) Oral Solution: U.S. Prescribing Information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/019651s025lbl.pdf
Zhang, Y., Dai, Y., & Zhang, Y. (2020). Efficacy of Citicoline for the Treatment of Acute Ischemic Stroke: A Meta-Analysis. Neuropsychiatric Disease and Treatment, 16, 2383–2391. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601330/
Shao, Y., Le, W., & Zhang, Y. (2019). Citicoline (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database of Systematic Reviews, (4). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741724/
Citicoline: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB12153
PubChem. (n.d.-q). Citicoline. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/citicoline

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

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