Gluconorm P 15 Tablet 10

Lupin Ltd

Strip of 10 Units

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MRP ~~₹162.7~~

₹130.16

₹16.27/Units

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Composition

Metformin (500 Mg) + Pioglitazone (15 Mg)

Gluconorm P 15 Tablet is used to manage high blood sugar levels in people with type 2 diabetes mellitus. It is a combination medicine that belongs to a class of medications known as oral antidiabetic agents.

This medicine helps when diet, exercise, and single medicines are insufficient to control blood sugar levels. It works by improving insulin sensitivity and decreasing glucose production in the body, which helps maintain normal blood sugar levels throughout the day.

You should take this medicine exactly as your doctor has prescribed. Before starting this medicine, inform your doctor about any pre-existing health conditions you have or any other medicines you are currently taking. If you notice any unusual side effects while using this medicine, notify your doctor promptly. Continue taking the medicine for the full duration prescribed by your doctor to get the most benefit.

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Gluconorm P 15 Tablet is used for the following:

Management of type 2 diabetes mellitus
Control of high blood sugar levels
Improving insulin sensitivity in the body
Second-line treatment when single medicines fail
Decreasing glucose production in the liver
Enhancing peripheral glucose uptake and utilisation
Regulating glucose metabolism
Regulating lipid metabolism

Swallow the tablet whole with a glass of water.
Do not crush, break, or chew the tablet.
Keep the medication in its original packaging and protect it from light and moisture.
If you have any questions about how to take this medicine, consult your doctor.

Gluconorm P 15 Tablet is taken orally.

Gluconorm P 15 Tablet may have the following common side effects:

Headache
Diarrhoea
Abdominal pain
Myalgia: This refers to muscle pain or aching that can occur in any part of your body.
Sinusitis: This is inflammation of the sinuses, causing pain and pressure around your nose, eyes, and forehead.
Upper respiratory tract infection
Oedema: This is swelling caused by fluid build-up in the body tissues, often noticeable in the ankles, feet, and legs.
Weight gain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gluconorm P 15 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Diarrhoea: Try taking Gluconorm P 15 Tablet with meals to reduce the likelihood of this side effect.
Abdominal pain: Taking this medicine after food rather than on an empty stomach may help minimise stomach discomfort.

Gluconorm P 15 Tablet contains two active ingredients that work together to control blood sugar:

Metformin (500 mg): As an antidiabetic agent, metformin decreases the amount of glucose your liver produces and improves how your body responds to insulin, helping muscle cells use glucose more effectively.
Pioglitazone (15 mg): This component activates special receptors called peroxisome proliferator-activated receptor gamma (PPARγ) in your body. These receptors help control the genes involved in glucose and fat metabolism, improving insulin sensitivity in fat tissues, muscles, and the liver.

Pregnancy

Gluconorm P 15 Tablet is not recommended during pregnancy, especially during the second and third trimesters. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while taking Gluconorm P 15 Tablet if you are breastfeeding. Metformin, one of the ingredients, passes into breast milk. It is best to consult your doctor before taking this medicine, as they can help weigh the benefits against potential risks to your baby.

Alcohol

Avoid alcohol while taking Gluconorm P 15 Tablet. Drinking alcohol with this medicine may increase your risk of developing lactic acidosis (a dangerous build-up of acid in your blood) and can affect your blood sugar control.

Liver

Caution is advised while taking Gluconorm P 15 Tablet if you have liver problems. This medicine may affect liver function. If you have a history of liver disease, inform your doctor before starting this medicine.

Kidney

Gluconorm P 15 Tablet is not recommended for use if you have severe kidney problems. Your doctor should check your kidney function before and during treatment, as metformin is removed from your body through the kidneys.

Using Machines & Driving

You may drive and use machines while taking Gluconorm P 15 Tablet unless you experience dizziness or low blood sugar (hypoglycaemia). If you notice these effects, avoid driving or operating complex machinery until you feel better.

Allergy

Do not take Gluconorm P 15 Tablet if you have a known allergy to metformin, pioglitazone, or any other ingredients in this medicine. Tell your doctor about any previous allergic reactions to medicines before starting treatment.

Children

Gluconorm P 15 Tablet is not recommended for children under 18 years of age. The safety and effectiveness of this medicine have not been established in children.

Older Patients

Older patients should take Gluconorm P 15 Tablet under medical supervision. If you are elderly, you may be more prone to side effects, including lactic acidosis, heart failure, and bone fractures. Your doctor may start you on a lower dose and monitor you more closely.

Drug-Drug Interactions

Gluconorm P 15 Tablet can interact with the following medicines:

CYP2C8 Inhibitors: Medicines like gemfibrozil may increase pioglitazone concentrations in your blood, raising the risk of side effects. Dose reduction might be necessary.
CYP2C8 Inducers: Medicines like rifampin can decrease pioglitazone levels, potentially reducing the effectiveness of Gluconorm P 15 Tablet.
Carbonic Anhydrase Inhibitors: Medicines such as topiramate and zonisamide may increase your risk of lactic acidosis (a serious condition where lactic acid builds up in your blood) when taken with metformin.
Corticosteroids: Medicines like prednisolone and dexamethasone can raise your blood sugar levels, potentially reducing the effectiveness of Gluconorm P 15 Tablet.

Drug-Food Interactions

Drug-Disease Interactions

Gluconorm P 15 Tablet may interact with the following diseases:

Heart failure: Pioglitazone can cause fluid retention and worsen heart failure, especially in patients with NYHA Class III or IV heart failure.
Bladder cancer: Pioglitazone may increase the risk of bladder cancer. It should not be used if you have active bladder cancer.

Daily Dose

The daily dose of Gluconorm P 15 Tablet should be taken as prescribed by your doctor. The dosage may vary based on your blood sugar levels and how well your body responds to the medicine. Follow your doctor's instructions carefully.

Over Dose

Taking too much of this medicine may cause low blood sugar (hypoglycaemia), stomach discomfort, nausea, or swelling in your legs and ankles. Contact your doctor if you experience these symptoms after taking an extra dose.

Missed Dose

If you forget to take Gluconorm P 15 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double your dose.

Store Gluconorm P 15 Tablet in its original packaging.
Always store the tablet below 30°C.
Keep the medicine protected from light and moisture.
Store in a dry place away from direct sunlight.
Keep all medicines out of reach of children.
Do not use this medicine after the expiry date printed on the package.

Monitor your carbohydrate intake by limiting sugary foods and refined carbohydrates, as this helps maintain stable blood glucose (sugar) levels when managing type 2 diabetes.
Engage in regular physical activity (at least 30 minutes daily) to improve insulin sensitivity, which helps your body use glucose more effectively.

Fact Box

Drug Category	Insulin sensitiser
Therapeutic Category	Anti-diabetic medication
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Type 2 diabetes, Insulin resistance

What is Gluconorm P 15 Tablet used for?

It is used to manage type 2 diabetes when diet, exercise, and single medicines don't adequately control blood sugar levels. It contains metformin and pioglitazone, which work together to lower glucose.

How does Gluconorm P 15 Tablet work in the body?

Metformin reduces glucose production in your liver, while pioglitazone makes your cells more responsive to insulin. Together, they improve how your body uses insulin to control blood sugar.

What should I do if I miss a dose?

Take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue your regular schedule. Don't take extra tablets to make up.

Can I take Gluconorm P 15 Tablet with insulin?

Yes, you can take it alongside insulin, but this combination may increase your risk of low blood sugar (hypoglycaemia). Always seek your doctor's advise before making any changes to your medications. This is so the you can be monitored closely when starting or adjusting either medicine.

What are the common side effects I should know about?

Common side effects include headache, respiratory infections, stomach problems (diarrhoea, nausea, tummy pain), muscle pain, weight gain, and fluid retention (oedema).

Is Gluconorm P 15 Tablet safe during pregnancy?

This medicine is not recommended during pregnancy.

How should I store Gluconorm P 15 Tablet?

Store away from light and moisture at temperatures below 30°C in the original packaging. Keep all medicines out of children's reach.

Last Updated On 24 Apr. 2025 | 7:57AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

Expiry on or after: November 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed - PIOGLITAZONE tablet. (n.d.-b). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5e36173a-2b5f-4ed7-bf81-6e79d78df0c4
PubChem. (n.d.-e). Pioglitazone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Pioglitazone
Singh, G., Can, A. S., & Correa, R. (2023, July 4). Pioglitazone. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK544287/
DailyMed - METFORMIN HYDROCHLORIDE- metformin tablet. (n.d.-c). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=45cc673a-e125-4d76-8013-89a089eb0ae9
PubChem. (n.d.-e). Metformin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Metformin
Metformin: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a696005.html

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

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