Biodib M 15 Tablet 10 is a combination oral antidiabetic medicine used to treat type 2 diabetes mellitus in adults. It helps lower blood glucose levels when diet, exercise, and single antidiabetic medicines are not sufficient to achieve adequate blood sugar control.
It contains pioglitazone and metformin. Take this tablet with food as prescribed by your doctor to reduce stomach discomfort. Swallow it whole and do not crush or chew extended-release tablets. Take it regularly to maintain steady blood sugar levels.
Lifestyle management is essential in type 2 diabetes care. Follow a healthy, balanced diet with controlled carbohydrate intake, engage in regular physical activity, monitor your blood sugar levels regularly, and avoid smoking and excessive alcohol consumption.
Before taking this medicine, inform your doctor if you have heart failure, kidney or liver conditions, or a history of bladder cancer. Seek immediate medical attention if you experience unusual fatigue, severe muscle pain, or swelling in your feet or ankles. It is not recommended during pregnancy or breastfeeding.
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Biodib M 15 Tablet 10
Strip of 10 Units
MRP ₹120
₹42
₹4.2/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Biodib M 15 Tablet 10
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Uses of Biodib M 15 Tablet 10
Biodib M 15 Tablet 10 is used in the long-term management of high blood sugar in adults with type 2 diabetes mellitus.
Uses of Biodib M 15 Tablet 10 are:
- Type 2 Diabetes Management: Helps lower fasting and post-meal blood sugar levels in adults.
- Improved Insulin Sensitivity: Reduces insulin resistance in body tissues to allow better glucose utilization.
- Prevention of Diabetic Complications: Helps reduce the long-term risk of kidney, nerve, and eye complications from high blood sugar.
Directions for Use of Biodib M 15 Tablet 10
Follow these instructions while taking Biodib M 15 Tablet 10:
Swallow the tablet whole with a glass of water.
Do not break, crush, or chew the tablet as it is an extended-release formulation.
Take this medicine regularly at the same time each day.
Do not stop taking this medicine suddenly without consulting your doctor.
If you miss taking your medicine, consult your doctor for advice.
Route of Administration
Biodib M 15 Tablet 10 is taken orally.
Side Effects of Biodib M 15 Tablet 10
Biodib M 15 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Biodib M 15 Tablet 10:
- Digestive: Feeling sick (nausea), loose motions (diarrhoea), and stomach pain.
- Neurological: Headache.
- Circulatory: Fluid retention causing swelling in the ankles, feet, or hands (oedema).
- Respiratory: Common cold symptoms or upper respiratory tract infections.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Biodib M 15 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:
Nausea: Taking Biodib M 15 Tablet 10 with meals can help reduce feelings of sickness.
Diarrhoea: Try taking this medicine with food to lessen this digestive disturbance.
How Biodib M 15 Tablet 10 Works?
Biodib M 15 Tablet 10 contains two active ingredients that work together to control blood glucose levels:
Pioglitazone (15 mg): Acting as a peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonist, it improves insulin sensitivity in fat tissue, skeletal muscle, and the liver, enabling your body to use insulin more efficiently.
Metformin (500 mg): This is a biguanide that enhances insulin sensitivity in peripheral tissues such as muscles, allowing your cells to absorb and use glucose more effectively.
Safety Measures & Warnings
Pregnancy
Take care while taking Biodib M 15 Tablet 10 if you are pregnant. It is ideal to discuss with your doctor before taking this medicine.
Breastfeeding
Be careful while taking Biodib M 15 Tablet 10 if you are breastfeeding. Both metformin and pioglitazone can pass into breast milk. It is best to talk with your doctor before taking this medicine.
Alcohol
Avoid alcohol while taking Biodib M 15 Tablet 10. Combining alcohol with this medicine may increase your risk of developing lactic acidosis (a condition where there's too much acid in your blood) and low blood sugar.
Liver
Biodib M 15 Tablet 10 should be used carefully if you have mild to moderate liver issues. Regular monitoring of liver function may be needed during treatment.
Kidney
Care is advised before using Biodib M 15 Tablet 10 if you have a history of kidney problems. This medicine contains metformin, which is removed from your body by your kidneys. It is a good idea to discuss this with your doctor before taking it.
Use In Driving And Operating Machinery
You may drive and use machines while taking Biodib M 15 Tablet 10. However, if you experience dizziness or low blood sugar symptoms, avoid these activities until you feel better.
Allergy
Inform your doctor about any previous allergic reactions to metformin, pioglitazone, or other medicines. Stop taking this medicine and seek immediate medical help if you develop a rash, itching, swelling, or breathing difficulties.
Children
Biodib M 15 Tablet 10 is not recommended for children as it is meant for managing type 2 diabetes in adults. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Biodib M 15 Tablet 10 under medical supervision, as they may be more sensitive to side effects. They might also have liver and kidney issues and might be on other medications.
Interactions of Biodib M 15 Tablet 10
Drug-Drug Interactions
Biodib M 15 Tablet 10 interacts with the following medicines:
Cationic medicines: Medications like amiloride, digoxin, and morphine may reduce metformin elimination, potentially increasing the risk of side effects.
Carbonic anhydrase inhibitors: Medicines such as topiramate and zonisamide can increase your risk of lactic acidosis (dangerous acid buildup in your blood) when taken with Biodib M 15 Tablet 10.
CYP2C8 inhibitors: Medicines like gemfibrozil may enhance pioglitazone exposure in your body, potentially increasing side effects.
Insulin or insulin secretagogues: Using these with Biodib M 15 Tablet 10 can increase your risk of hypoglycaemia (low blood sugar).
Drug-Disease Interactions
Biodib M 15 Tablet 10 interacts with the following diseases:
Kidney impairment: This medicine is not recommended if you have severe kidney problems (eGFR below 30 ml/min/1.73m²) due to the increased risk of lactic acidosis.
Liver impairment: Use with caution if you have liver problems as it may affect how your body processes the medicine.
Congestive heart failure: The Pioglitazone component may worsen fluid retention in patients with heart failure.
Metabolic acidosis: This medicine is not recommended if you have this condition, as it may worsen the acid imbalance.
Dosage of Biodib M 15 Tablet 10
Daily Dose
The daily dose of Biodib M 15 Tablet 10 should be taken as prescribed by your doctor. Your dosage may vary based on your blood glucose levels and how well you respond to treatment. Never change your dose without consulting your doctor.
Over Dose
Taking more than the prescribed dosage of Biodib M 15 Tablet 10 may cause stomach discomfort, nausea, vomiting, diarrhoea, excessive hunger, sweating, and dizziness. You might also experience swelling in your legs and ankles. Contact your doctor if these symptoms occur.
Missed Dose
If you forget to take Biodib M 15 Tablet 10, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never double your dose to make up for a missed one.
Storage
Store Biodib M 15 Tablet 10 at room temperature (below 30°C).
Keep the tablets in their original container and protected from light and moisture.
Store in a dry place away from direct heat or sunlight.
Keep all medicines out of sight and reach of children.
Do not use this medicine after the expiry date printed on the packaging.
Special Dietary And Lifestyle Recommendation
Follow a low-carbohydrate diet with plenty of vegetables, whole grains, and lean proteins to help manage your blood glucose levels and improve insulin sensitivity.
Engage in regular physical activity, such as brisk walking for 30 minutes daily. Exercise helps your body use glucose more effectively and reduces insulin resistance.
Fact Box
| Dosage Forms Available | Tablet ER |
| Habit Forming | No |
| Ailment | Type 2 diabetes |
| Drug Category | Insulin sensitiser |
| Therapeutic Category | Anti-diabetic medication |
Frequently Asked Questions (FAQs)
What is Biodib M 15 Tablet 10 used for?
Biodib M 15 Tablet 10 is used to manage type 2 diabetes when diet, exercise, or single medicines alone don't control your blood sugar levels adequately.
How does Biodib M 15 Tablet 10 work?
It works through two mechanisms: metformin reduces glucose production in your liver, while pioglitazone helps your body use insulin more effectively.
Can I stop taking Biodib M 15 Tablet 10 after I feel better?
No, don't stop taking this medicine even if you feel better. Stopping suddenly can cause your blood sugar levels to rise dangerously.
What are the common side effects of Biodib M 15 Tablet 10?
Common side effects include stomach discomfort, nausea, diarrhoea, headache, and mild swelling. Most side effects typically improve with time.
Can I take Biodib M 15 Tablet 10 during pregnancy?
The safety during pregnancy isn't fully established. Consult your doctor if you're pregnant or planning pregnancy before taking this medicine.
Should I take Biodib M 15 Tablet 10 with or without food?
Take this medicine with meals. This helps reduce stomach-related side effects and improves how your body absorbs the medicine.
What should I do if I miss a dose of Biodib M 15 Tablet 10?
Take the missed dose as soon as you remember. If it's nearly time for your next dose, skip the missed dose and continue with your regular schedule.
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Country of origin: INDIA
References
Ceriello, A., Johns, D., Widel, M., Eckland, D. J., Gilmore, K. J., & Tan, M. H. (2005). Comparison of effect of pioglitazone with metformin or sulfonylurea (monotherapy and combination therapy) on postload glycemia and composite insulin sensitivity index during an oral glucose tolerance test in patients with type 2 diabetes. Diabetes Care, 28(2), 266-272.https://doi.org/10.2337/diacare.28.2.266
Kaku, K. (2009). Efficacy and safety of therapy with metformin plus pioglitazone in the treatment of patients with type 2 diabetes: a double-blind, placebo-controlled clinical trial. Current Medical Research and Opinion, 25(5), 1111-1119. https://doi.org/10.1185/03007990902820816
Pioglitazone: MedlinePlus drug information. (2024, December 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a699016.html
Metformin - StatPearls - NCBI bookshelf. (2023, August 17). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK518983/
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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