Glucobay M 50 Tablet 10

Bayer Zydus Pharma Private Limited

Strip of 10 Units

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MRP ~~₹187~~

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Composition

Acarbose (50 Mg) + Metformin (500 Mg)

Glucobay M 50 Tablet 10 is used to manage Type 2 Diabetes mellitus by controlling blood sugar levels. It is a combination medicine that belongs to the class of antidiabetic medications.

In addition to controlling blood sugar, this medicine helps improve glycaemic control through multiple mechanisms. It is particularly beneficial for patients whose blood sugar levels are not adequately managed by single medicines alone. The combination provides a synergistic effect in managing high blood sugar levels.

The medicine should be taken as directed by your doctor. Before starting this medicine, inform your doctor about any pre-existing conditions you may have or any other medicines you are currently taking. If you experience any side effects while using this medicine, notify your doctor promptly. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Glucobay M 50 Tablet 10 is used for the following:

Managing type 2 diabetes mellitus
Controlling blood sugar levels
Improving glycaemic control in adults
Reducing postprandial hyperglycaemia
Supplementing diet and exercise for diabetes management
Regulating fasting blood glucose levels
Helping patients uncontrolled on single medicine therapy
Preventing diabetic complications

Follow these instructions while taking Glucobay M 50 Tablet 10:

Swallow the tablet whole with a full glass of water.
Do not crush, chew, or split the tablet.
Maintain a regular schedule for taking this medicine.

Glucobay M 50 Tablet 10 is taken orally.

Glucobay M 50 Tablet 10 may have the following common side effects:

Flatulence
Diarrhoea
Abdominal pain
Nausea
Vomiting
Rash
Headache
Weakness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glucobay M 50 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Flatulence: Taking Glucobay M 50 Tablet 10 with the first bite of a main meal can help reduce gas formation.
Nausea: Try taking this medicine with food rather than on an empty stomach to minimise feelings of sickness.

Glucobay M 50 Tablet 10 contains two active ingredients:

Acarbose (50 mg): This component works as an alpha-glucosidase inhibitor in your intestines. It slows down the digestion of complex carbohydrates (starches and sugars) by blocking specific enzymes, which delays glucose absorption and reduces post-meal blood sugar spikes.
Metformin (500 mg): As a biguanide, metformin decreases glucose production in your liver by inhibiting processes called gluconeogenesis and glycogenolysis. It also improves insulin sensitivity in your body tissues, helping them absorb and use glucose more effectively.

Pregnancy

Caution is advised while taking Glucobay M 50 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Glucobay M 50 Tablet 10 during breastfeeding. Discuss with your doctor before using this medicine if you are nursing.

Alcohol

Avoid alcohol while taking Glucobay M 50 Tablet 10. Drinking alcohol with this medicine increases your risk of developing lactic acidosis (a serious condition where there is too much acid in your blood) and low blood sugar levels.

Liver

Caution is advised while taking Glucobay M 50 Tablet 10 in case of mild to moderate liver impairment. It is contraindicated for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Glucobay M 50 Tablet 10 is contraindicated if you have kidney problems. Your doctor may check your kidney function before prescribing this medicine.

Using Machines & Driving

If you experience dizziness or low blood sugar after using Glucobay M 50 Tablet 10, avoid driving or operating heavy machinery until you feel better.

Allergy

This medicine is contraindicated if you are hypersensitive (allergic) to acarbose, metformin, or any other ingredients in the tablet. Inform your doctor if you have any allergies before taking Glucobay M 50 Tablet 10.

Children

Caution is advised while giving Glucobay M 50 Tablet 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Glucobay M 50 Tablet 10 under medical supervision. Elderly people may be more susceptible to side effects, especially if they have kidney or liver problems. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Glucobay M 50 Tablet 10 interacts with the following medicines:

Insulin secretagogues: Medicines like glimepiride or gliclazide may increase the risk of hypoglycaemia (low blood sugar) when taken with Glucobay M 50 Tablet 10.
Cationic medicines: Medications such as digoxin, procainamide, or quinidine that are eliminated by renal tubular secretion may compete with metformin, affecting medication levels.
Carbonic anhydrase inhibitors: Medicines like acetazolamide or topiramate may increase the risk of lactic acidosis (dangerous build-up of lactic acid) when combined with metformin.
Digestive enzyme preparations: Products containing amylase or pancreatin may reduce acarbose's effectiveness by breaking down its structure.

Drug-Food Interactions

Glucobay M 50 Tablet 10 has minimal food interactions. However:

Carbohydrate-rich foods: May increase the likelihood of flatulence and diarrhoea due to the acarbose component's action on carbohydrate digestion.

Drug-Disease Interactions

Glucobay M 50 Tablet 10 interacts with the following diseases:

Renal impairment: This medicine may increase the risk of lactic acidosis in patients with kidney problems.
Hepatic impairment: Patients with liver disease should not use this medicine, as it may worsen their condition.
Diabetic ketoacidosis: This medicine is not suitable for patients experiencing this acute complication of diabetes.
Conditions causing tissue hypoxia: Situations like heart attack, severe infection, or cardiovascular collapse increase the risk of lactic acidosis with this medicine.

Daily Dose

The daily dose of Glucobay M 50 Tablet 10 should be taken as prescribed by your doctor. The dosage may vary based on your blood sugar levels and how well you respond to treatment. Never change your dosage without consulting your doctor first.

Over Dose

Overdosing on Glucobay M 50 Tablet 10 may cause stomach problems, diarrhoea, excessive gas, and abdominal pain. You might also experience weakness and dizziness. Contact your doctor if these symptoms occur.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one. Never take a double dose to make up for the missed one.

Keep at room temperature not exceeding 30°C.
Protect from light and moisture in its original packaging.
Store in a dry place away from direct sunlight.
Keep out of reach of children.
Do not use after the expiry date printed on the package.

Limit your intake of carbohydrate-rich foods such as white rice, potatoes, and sweets, as these can cause sharp rises in blood glucose (blood sugar) levels that Glucobay M 50 Tablet 10 helps to control.
Engage in regular physical activity, such as walking for 30 minutes daily, to improve insulin sensitivity, which helps your body use glucose more effectively alongside the action of metformin in this medicine.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes, Hyperglycaemia, Blood sugar control
Drug Category	Alpha-glucosidase inhibitor + Biguanide
Therapeutic Category	Antidiabetic medication

What is Glucobay M 50 Tablet 10 and how does it work?

Glucobay M 50 Tablet 10 contains acarbose and metformin to manage type 2 diabetes. It slows carbohydrate digestion and reduces glucose production in your liver.

Can Glucobay M 50 Tablet 10 cause stomach problems?

Yes, you might experience flatulence (gas), diarrhoea, or stomach discomfort, especially when starting the medicine. These side effects usually decrease over time.

Should I take Glucobay M 50 Tablet 10 before or after meals?

Take this medicine with the first bite of your main meals. This timing helps the acarbose component work effectively to slow down carbohydrate digestion.

Can I drink alcohol while taking Glucobay M 50 Tablet 10 ?

No, avoid alcohol while taking this medicine. Alcohol increases your risk of lactic acidosis, a rare but serious condition that affects blood chemistry.

What should I do if I miss a dose?

If you miss a dose, take it with your next meal. However, if it is almost time for your next regular dose, skip the missed one. Never take double doses.

Will Glucobay M 50 Tablet 10 affect my vitamin B12 levels?

Long-term use may reduce vitamin B12 absorption. Your doctor might recommend periodic blood tests to check your levels during extended treatment.

Can I take Glucobay M 50 Tablet 10 with insulin?

Yes, but with caution. Using both together may increase your risk of low blood sugar (hypoglycaemia). Your doctor may need to adjust your insulin dose.

Last Updated On 23 May. 2025 | 7:50AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

7238+35P, Digvijay Cooperative Housing Society, Kalher, Bhiwandi, Maharashtra 421302

Country of origin: INDIA

Expiry on or after: November 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MedlinePlus. (n.d.). Metformin. U.S. National Library of Medicine. Retrieved 1 April 2025, from https://medlineplus.gov/druginfo/meds/a696005.html
U.S. Food and Drug Administration. (2011). PRECOSE (acarbose tablets), USP [Label]. Retrieved 1 April 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020482s024lbl.pdf
U.S. National Library of Medicine. (n.d.). ACARBOSE – acarbose tablet [DailyMed]. Retrieved 1 April 2025, from https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=6cd185e6-3205-484c-be49-456acfc7eb11&type=display
Foretz, M., Guigas, B., & Viollet, B. (2023). Metformin: Update on mechanisms of action and repurposing potential. Nature Reviews Endocrinology, 19(8), 460–476. https://doi.org/10.1038/s41574-023-00833-4
Corcoran, C., & Jacobs, T. F. (2023, August 17). Metformin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK518983/
McIver, L. A., Preuss, C. V., & Tripp, J. (2024, February 12). Acarbose. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK493214/

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Chandrasekhar Swaminathan

Email: grievance-officer@truemeds.in

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