Kerendia 10mg Tablet is used to slow the progression of kidney damage in patients with chronic kidney disease (CKD) associated with type 2 diabetes. It is a specialized renal-protective agent that significantly reduces the risk of heart failure, kidney failure, and cardiovascular death. By protecting the heart and kidneys simultaneously, it helps manage the complex complications often seen in diabetic patients.
The active ingredient, Finerenone, works by blocking the mineralocorticoid receptor (MR) overactivation, which is known to contribute to inflammation and scarring in the heart and kidneys. By reducing this overactivation, the medicine helps slow the decline of the estimated glomerular filtration rate (eGFR) and protects against end-stage kidney disease. It is a vital advancement in the long-term management of diabetic kidney complications.
Consult your doctor for the appropriate dosage based on your kidney function tests and electrolyte levels. It is essential to monitor your potassium levels regularly while on this medication. Always inform your healthcare provider about any pre-existing heart conditions or other medications you are taking to ensure safe and effective therapy.
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Kerendia 10mg Tablet 14
Bayer Zydus Pharma Private Limited
Strip of 14 Units
Old MRP ₹1495
MRP ₹1401.56
₹1121.25
₹100.11/Units
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CompositionAbout Kerendia 10mg Tablet 14
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Uses of Kerendia 10mg Tablet 14
Kerendia 10mg Tablet is used in adults with type 2 diabetes and chronic kidney disease (CKD) to help slow kidney damage. It reduces the risk of kidney failure, heart problems, and hospitalization, and protects overall heart and kidney health. This medication plays a crucial role in managing CKD and preventing complications in diabetic patients.
Directions for Use of Kerendia 10mg Tablet 14
- Swallow the tablet whole with a glass of water.
- You can take the tablet with or without food.
- Do not crush, chew, or split the tablet.
- Follow your doctor’s prescribed dosage carefully.
Route of Administration
Kerendia 10 mg Tablet is taken orally.
Side Effects of Kerendia 10mg Tablet 14
Kerendia 10 mg Tablet may cause common side effects such as hyperkalemia (high potassium levels), hypotension (low blood pressure), and hyponatremia (low sodium levels). If you experience serious side effects, such as severe symptoms of hyperkalemia (e.g., muscle weakness, irregular heartbeat), contact your healthcare provider immediately.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Kerendia 10 mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are two tips for managing common side effects:
- Hyperkalemia: Avoid potassium-rich foods and consult your doctor about dietary modifications.
- Hypotension: Stay hydrated and avoid sudden position changes to prevent dizziness.
How Kerendia 10mg Tablet 14 Works?
Kerendia 10 mg Tablet contains Finerenone (10 mg), which works as follows:
- It works by selectively blocking the mineralocorticoid receptor, reducing inflammation and fibrosis in the kidneys and heart. This helps slow CKD progression and mitigates cardiovascular risks associated with type 2 diabetes.
Safety Measures & Warnings
Pregnancy
You should not take this medicine during pregnancy unless your doctor states it is clearly necessary. Consult your doctor if you are pregnant or planning to become pregnant.
Breastfeeding
Kerendia 10 mg Tablet is not recommended during breastfeeding. Inform your doctor before this tablet is prescribed.
Alcohol
Alcohol consumption may increase the risk of side effects like dizziness or low blood pressure. Avoid or limit alcohol intake during treatment.
Liver
This tablet is not recommended in patients with severe hepatic impairment. Patients with mild to moderate hepatic impairment should use Kerendia 10 mg Tablet with caution. Regular liver function tests may be required. Inform your doctor if you have a history of liver disease.
Kidney
Kerendia 10 mg Tablet is primarily indicated for patients with kidney disease, but it should be used carefully in patients with advanced renal impairment. Monitor kidney function and serum potassium levels regularly.
Use In Driving And Operating Machinery
Kerendia 10 mg Tablet may cause dizziness. Avoid driving or operating heavy machinery until you know how the medication affects you.
Allergy
Do not use Kerendia 10 mg Tablet if you are allergic to Finerenone or any of its components. Seek immediate medical attention if you experience symptoms of an allergic reaction, such as rash, itching, or difficulty breathing.
Children
Kerendia 10 mg Tablet is not recommended for patients under 18 years of age.
Older Patients
Elderly patients should use Kerendia 10 mg Tablet with caution due to the increased risk of hyperkalemia. Regular monitoring is essential.
Interactions of Kerendia 10mg Tablet 14
Drug-Drug Interactions
Kerendia 10 mg Tablet interacts with the following medicines:
- Strong CYP3A4 Inhibitors such as ketoconazole, and clarithromycin: Concomitant use is contraindicated as it increases Finerenone levels.
- Moderate or Weak CYP3A4 Inhibitors such as verapamil, diltiazem: Monitor potassium levels and adjust Kerendia 10 mg Tablet dosage as needed.
- Potassium-Sparing Diuretics or Supplements: The concomitant use can increased the risk of hyperkalemia.
Drug-Food Interactions
Avoid grapefruit or grapefruit juice during treatment as it may increase Finerenone levels.
Drug-Disease Interactions
Kerendia 10 mg Tablet interacts with the following diseases:
- Adrenal Insufficiency: Avoid use in patients with adrenal insufficiency.
- Hyperkalemia: Patients with baseline high potassium levels should be closely monitored.
Dosage of Kerendia 10mg Tablet 14
Daily Dose
Take the daily recommended dose of Kerendia 10 mg Tablet as directed by your doctor. The dosage may vary depending on factors like your health condition and how you respond to the medicine. Make sure you stick to the prescribed dosage and consult your doctor before making any changes.
Over Dose
Taking more than the prescribed dose can increase the risk of hyperkalemia or other side effects. If you suspect an overdose, contact your healthcare provider immediately.
Missed Dose
If you forget to take Kerendia 10 mg Tablet at the scheduled time, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your usual schedule. Never alter your dosage without consulting your doctor.
Storage
- Store Kerendia 10 mg Tablet in a cool, dry place away from direct sunlight.
- Keep the medication out of reach of children.
- Do not use after the expiry date printed on the package.
Special Dietary And Lifestyle Recommendation
- Follow a low-potassium diet to minimise the risk of hyperkalemia. Avoid foods like bananas, oranges, and potatoes unless otherwise advised.
- Stay hydrated and avoid dehydration, which can affect kidney function.
- Maintain a healthy lifestyle with regular physical activity suitable for your condition.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Chronic Kidney Disease, Cardiovascular Complications |
| Drug Category | Non-Steroidal Mineralocorticoid Receptor Antagonist (MRA) |
| Therapeutic Category | Cardiovascular and Renal Protective Agent |
Frequently Asked Questions (FAQs)
What is Kerendia 10 mg Tablet used for?
This tablet is used to reduce the risk of kidney and cardiovascular complications in adults with CKD associated with type 2 diabetes.
How does Kerendia 10 mg Tablet work?
This tablet blocks the mineralocorticoid receptor, reducing inflammation and fibrosis in the kidneys and heart.
What are the side effects of Kerendia 10 mg Tablet?
The common side effects include hyperkalemia, hypotension, and hyponatremia. Report any severe or persistent side effects to your doctor.
Can Kerendia 10 mg Tablet interact with other medications?
Yes, this tablet interacts with strong CYP3A4 inhibitors, potassium-sparing diuretics, and certain other medications. Always inform your doctor about your current medications.
Is Kerendia 10 mg Tablet safe during pregnancy and breastfeeding?
You should not take this medicine during pregnancy unless your doctor states it is clearly necessary. This tablet is not recommended during breastfeeding.
Can I take Kerendia 10 mg Tablet with grapefruit juice?
No, avoid grapefruit juice as it may increase the levels of Finerenone in your body.
What should I do if I miss a dose?
Take the missed dose as soon as you remember, but skip it if it is close to your next dose. Never double your dose.
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Manufacturer details
Country of origin: GERMANY
References
- Warnings, -----------------------, & ----------------------, P. (n.d.). This label may not be the latest approved by FDA. For current labeling information, please visit https://www.fda.gov/drugsatfda. Fda.Gov. Retrieved January 14, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/215341s000lbl.pdf
- Kerendia Tablet. (N.d.). Org.Uk. Retrieved January 14, 2025, from https://www.medicines.org.uk/emc/files/pil.13438.pdf
- Kerendia 10 mg film-coated tablets. (N.d.). Europa.Eu. Retrieved January 14, 2025, from https://ec.europa.eu/health/documents/community-register/2022/20220216154593/anx_154593_en.pdf
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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