Fexuclue Tablet 10 is used for the treatment of erosive oesophagitis in adults. It belongs to a class of medicines known as potassium-competitive acid blockers.
Oesophagitis commonly occurs as a complication of gastro-oesophageal reflux disease (GERD) and may lead to symptoms such as heartburn, chest discomfort, acid regurgitation, and difficulty swallowing. When used as prescribed, this tablet helps relieve inflammation, promotes mucosal recovery, and prevents further acid-induced injury.
Before starting Fexuclue Tablet 10, consultation with your doctor is essential. The dosage and duration of therapy depend on the severity of oesophageal damage, symptom persistence, liver and kidney function, and overall health status. Any unexpected symptoms or side effects observed during treatment should be reported promptly. Consistent use as prescribed is necessary to achieve optimal results.
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Fexuclue Tablet 10
Strip of 10 Units
Old MRP ₹280
MRP ₹262.5
₹210
₹26.25/Units
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CompositionAbout Fexuclue Tablet 10
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Uses of Fexuclue Tablet 10
Fexuclue Tablet 10 is used for:
- Treatment of erosive oesophagitis
- Healing of acid-related damage to the oesophagus
- Relief of symptoms associated with gastro-oesophageal reflux disease
Directions for Use of Fexuclue Tablet 10
- Swallow the tablet whole with water.
- Do not crush, chew, or split the tablet.
- Fexuclue Tablet 10 may be taken with or without food.
- Take the tablet once daily at the same time each day for optimal acid control.
Route of Administration
Fexuclue Tablet 10 is taken orally.
Side Effects of Fexuclue Tablet 10
Fexuclue Tablet 10 may cause the following side effects:
- Dizziness
- Altered taste sensation
- Muscle pain
- Skin itching or rash
- Facial swelling
- Chest discomfort
- Runny nose
- Gastrointestinal discomfort
Managing the Side Effects:
Most side effects are mild and resolve during continued use or after completion of therapy. Consult your doctor if symptoms persist or worsen.
- Dizziness: Avoid sudden posture changes and ensure adequate hydration.
- Skin itching or rash: Maintain skin hydration and report persistent reactions.
- Muscle pain: Gentle stretching and adequate rest may help relieve discomfort.
How Fexuclue Tablet 10 Works?
Fexuclue Tablet 10 contains the following active component:
- Fexuprazan (40 mg): Fexuprazan is a potassium-competitive acid blocker that inhibits gastric acid secretion by reversibly blocking the potassium-binding site of the H⁺/K⁺-ATPase enzyme in gastric parietal cells. This results in rapid, sustained suppression of stomach acid production, supporting healing of acid-related oesophageal damage.
Safety Measures & Warnings
Pregnancy
Fexuclue Tablet 10 is not recommended during pregnancy Inform your doctor if you are pregnant or planning pregnancy.
Breastfeeding
Breastfeeding should be discontinued during treatment with Fexuclue Tablet 10, as it is not known whether fexuprazan passes into human breast milk.
Alcohol
Alcohol may aggravate gastric irritation and worsen reflux symptoms. Limiting or avoiding alcohol consumption during treatment is advised.
Liver
Fexuclue Tablet 10 should be cautiously used in patients with hepatic impairment. Inform your doctor about the existing liver condition before this tablet is prescribed.
Kidney
Fexuclue Tablet 10 should be cautiously used in patients with renal impairment. Inform your doctor about the existing kidney condition before this tablet is prescribed.
Using Machines & Driving
Fexuclue Tablet 10 may cause dizziness in some individuals. Avoid driving or operating machinery if such symptoms occur.
Allergy
Do not use Fexuclue Tablet 10 if you have a known hypersensitivity to fexuprazan, tartrazine, or any other component of the formulation. Seek immediate medical attention if allergic reactions occur.
Children
The safety and effectiveness of Fexuclue Tablet 10 in children and adolescents have not been established. Use is not recommended.
Older Patients
Elderly patients may have reduced liver or kidney function. Careful administration and monitoring are advised.
Interactions of Fexuclue Tablet 10
Drug-Drug Interactions
Fexuclue Tablet 10 interacts with the following medicines:
- HIV medications such as Atazanavir, nelfinavir, rilpivirine: It results in reduced absorption due to increased gastric pH; concurrent use is not recommended.
Drug-Disease Interactions
Fexuclue Tablet 10 should be used cautiously in patients with:
- Suspected gastric malignancy: Fexuclue Tablet 10 may relieve acid-related symptoms and potentially delay the diagnosis of gastric cancer; underlying malignancy should be ruled out before initiating therapy.
- Osteoporosis or fracture risk: Long-term acid suppression with Fexuclue Tablet 10 may impair calcium absorption, potentially increasing the risk of bone fractures, especially in susceptible patients.
- History of electrolyte imbalance: Fexuclue Tablet 10 may be associated with disturbances such as hypomagnesaemia during prolonged use, requiring periodic monitoring of electrolyte levels.
Dosage of Fexuclue Tablet 10
Daily Dose
The daily dose of Fexuclue Tablet 10 should be taken as prescribed. If erosive oesophagitis remains untreated or symptoms persist, treatment may be extended for a longer duration as advised by your doctor.
Over Dose
Overdose of Fexuclue Tablet 10 can cause dizziness and gastrointestinal discomfort. If these symptoms persist or worsen, inform your doctor.
Missed Dose
If a dose of Fexuclue Tablet 10 is missed, take it as soon as remembered. If it is close to the next scheduled dose, skip the missed dose. Do not take an additional dose to compensate.
Storage
- Store at room temperature in a dry place.
- Keep the tablet in the original container.
- Protect from moisture and heat.
- Keep out of reach and sight of children.
- Do not use after the expiry date stated on the packaging.
Diet & Lifestyle
- Avoid spicy, fatty, and acidic foods that may worsen reflux symptoms.
- Eat smaller, more frequent meals instead of large meals.
- Avoid lying down immediately after eating.
- Maintain a healthy body weight to reduce abdominal pressure.
- Elevate the head of the bed if night-time reflux occurs.
Fact Box
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Erosive oesophagitis |
| Drug Category | Potassium-competitive acid blocker |
| Therapeutic Category | Gastric acid suppressant |
Frequently Asked Questions (FAQs)
What is Fexuclue Tablet 10 used for?
Can children use Fexuclue Tablet 10?
Does Fexuclue Tablet 10 affect driving?
Can Fexuclue Tablet 10 be used for long-term acid suppression?
What should I do if my symptoms do not improve with Fexuclue Tablet 10?
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Manufacturer details
Country of origin: INDIA
References
- Fexuclue Tablet. (n.d.). Gov.Ph. Retrieved December 30, 2025, from https://verification.fda.gov.ph/files/DR-XY48448_PI_01.pdf
- Fexuclue 40 mg Tablet. (n.d.). Fexuprazan. Fexuprazan. Retrieved December 30, 2025, from https://www.fexuprazan.com/?lang=en
- Fexuprazan. (n.d.). Retrieved December 30, 2025, from https://go.drugbank.com/drugs/DB16078
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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