Diamicron Xr Mex 30/500 Tablet 15

Serdia Pharmaceuticals (India) Pvt. Ltd.

Strip of 15 Units

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MRP ~~₹125.2~~

₹100.16

₹8.35/Units

20% off

*MRP inclusive of all taxes

100% genuine medicines

Safe & secure payments

15 days Easy returns

Prescription required for this medicine

Store Below 30° C

Composition

Gliclazide (30 Mg) + Metformin (500 Mg)

Diamicron XR MEX 30/500 Tablet is used to manage type 2 diabetes in adults when treatment with one medicine does not control blood sugar adequately.

It contains gliclazide in a modified-release form, which helps the pancreas release insulin, and metformin, which improves the response to insulin and reduces the glucose the liver makes.

Take it with breakfast as prescribed, and do not skip that meal, as this can cause low blood sugar. Carry a fast-acting sugar source.

Tell your doctor about any kidney or liver problems, or if you drink alcohol regularly, before use. Seek urgent help for severe weakness or breathlessness, which can rarely signal lactic acidosis.

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Diamicron XR MEX 30/500 Tablet is used to manage type 2 diabetes.

Uses of Diamicron XR MEX 30/500 Tablet are:

Type 2 Diabetes: Helps control blood sugar when one medicine is not enough.
Combined Action: Increases insulin release and improves the response to insulin.
Steady Control: The modified-release form gives steady effect through the day.

Here is how to take Diamicron Xr Mex 30/500 Tablet 15:

Swallow the tablet whole with a full glass of water.
Do not split, crush, or chew the tablet.
This medicine should be taken once daily with your evening meal.
Always take this medicine exactly as directed by your doctor.

Diamicron Xr Mex 30/500 Tablet 15 is taken orally.

Diamicron XR MEX 30/500 Tablet may cause side effects, but not everyone gets them.

A few common side effects of Diamicron XR MEX 30/500 Tablet are:

Low Blood Sugar: Hypoglycaemia, with shakiness, sweating and a fast heartbeat; treat promptly with fast-acting sugar.
Digestive: Feeling sick (nausea), vomiting and diarrhoea; taking it with food may help.
Nervous System: Headache in some people.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Diamicron Xr Mex 30/500 Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hypoglycaemia: Carry a source of fast-acting glucose like sweets or a sugary drink with you at all times.
Nausea: Try taking Diamicron Xr Mex 30/500 Tablet 15 with food rather than on an empty stomach to reduce feelings of nausea.

Diamicron Xr Mex 30/500 Tablet 15 contains two active ingredients:

Gliclazide (30 mg): As a sulfonylurea, gliclazide stimulates the pancreas to produce more insulin. It works by binding to the sulfonylurea receptor on pancreatic beta-cell surfaces and blocking ATP-sensitive potassium channels. This action depolarises the beta-cell and opens voltage-dependent calcium channels, leading to an influx of calcium ions that stimulate insulin secretion.
Metformin (500 mg): Classified as a biguanide, metformin reduces glucose production by the liver and improves insulin sensitivity. It achieves these effects by activating AMP-activated protein kinase (AMPK), a liver enzyme that plays a crucial role in insulin signalling, whole body energy balance, and glucose and lipid metabolism.

Pregnancy

Diamicron Xr Mex 30/500 Tablet 15 is generally not recommended for use during pregnancy. Consult your doctor to explore safer alternatives if you are pregnant or planning to conceive.

Breastfeeding

Breastfeeding mothers should avoid taking Diamicron Xr Mex 30/500 Tablet 15, as its active ingredients can pass into breast milk, potentially affecting the infant. Consult your doctor for alternative options or discontinue breastfeeding if advised.

Alcohol

Avoid alcohol consumption while taking this medication, as it may intensify the blood sugar-lowering effect and increase the risk of lactic acidosis—a serious complication associated with metformin.

Liver

This medication is not recommended for patients with liver impairment due to the increased risk of adverse effects. Liver function may be further compromised with its use. Consult your healthcare provider if you have liver-related concerns.

Kidney

Diamicron Xr Mex 30/500 Tablet 15 is contraindicated in patients with severe renal impairment, as it may elevate the risk of lactic acidosis due to metformin accumulation. People with any history of kidney issues should discuss this with their doctor before starting the medication.

Use In Driving And Operating Machinery

As Diamicron Xr Mex 30/500 Tablet 15 may cause dizziness, caution is advised while driving or operating heavy machinery until you know how the medication affects you. Consult your doctor for guidance if you experience dizziness frequently.

Allergy

Avoid taking Diamicron Xr Mex 30/500 Tablet 15 if you are allergic to gliclazide, metformin, or any other excipients in the formulation. Discuss with your doctor any previous allergies or reactions to antidiabetic medications to determine suitable alternatives.

Children

This medication is not generally recommended for children unless specifically prescribed by a doctor. Always seek medical advice before administering this medicine to a child.

Older Patients

Elderly patients may be more susceptible to the side effects of Diamicron Xr Mex 30/500 Tablet 15 due to age-related declines in liver, kidney, and heart function. It is advisable for older patients to start at a lower dose as directed by their healthcare provider and take the medication under close medical supervision.

Drug-Drug Interactions

Diamicron Xr Mex 30/500 Tablet 15 can interact with medications, including:

ACE-Inhibitors: Medicines such as captopril and enalapril can enhance the blood sugar-lowering effects of Diamicron Xr Mex 30/500 Tablet 15.
Beta Blockers: Medications such as propranolol may intensify the blood glucose-lowering effects of gliclazide, leading to hypoglycaemia (low blood sugar).
Diuretics: Diuretics like furosemide may increase blood sugar levels, which could reduce the effectiveness of Diamicron Xr Mex 30/500 Tablet 15.
Antifungals: Miconazole and fluconazole can amplify the hypoglycaemic effect of gliclazide, increasing the risk of very low blood sugar levels.

Drug-Disease Interactions

Diamicron Xr Mex 30/500 Tablet 15 can interact with conditions, including:

Kidney Impairment: This medication should be avoided in individuals with severe renal impairment due to the increased risk of lactic acidosis.
Liver Impairment: Avoid using Diamicron Xr Mex 30/500 Tablet 15 if you have liver disease, as it may exacerbate liver issues.
Cardiovascular Disease: Patients with heart disease should use this medication with caution, as metformin can cause lactic acidosis, a rare but potentially serious side effect to which people with cardiovascular conditions are more susceptible.

Daily Dose

The daily dose of Diamicron Xr Mex 30/500 Tablet 15 should be taken strictly as directed by your doctor. The dosage may vary depending on individual factors such as your condition's severity and your response to the medicine. Never alter your dosage without consulting your doctor.

Over Dose

Overdose may lead to severe hypoglycaemia (due to gliclazide) or lactic acidosis (due to metformin), both of which can be life-threatening. Immediate medical attention is essential.

Missed Dose

If you forget to take your regular dose of Diamicron Xr Mex 30/500 Tablet 15, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed one and continue with your regular schedule. Don't increase your dosage without consulting your doctor.

Keep Diamicron Xr Mex 30/500 Tablet 15 in a dry place, away from light and moisture.
The ideal storage temperature should be below 30°C.
Always keep this medicine out of the reach of children.
Remember to use the medicine before the expiry date mentioned on the pack.

As Diamicron Xr Mex 30/500 Tablet 15 manages type 2 diabetes, maintaining a balanced diet low in sugar and high in fibre can be beneficial. This includes whole grains, fruits, vegetables, and lean proteins.
Regular exercise can help control your blood glucose levels. Engaging in physical activity like walking, yoga or cycling for at least 30 minutes every day can make a significant difference.

Fact Box

Dosage Forms Available	Tablet Er
Habit Forming	No
Ailment	Type 2 Diabetes
Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic

What is Diamicron Xr Mex 30/500 Tablet 15 used for?

Diamicron Xr Mex 30/500 Tablet 15 is an antidiabetic medicine used to control blood sugar levels in adults with type 2 diabetes mellitus.

How does Diamicron Xr Mex 30/500 Tablet 15 work?

This medication combines gliclazide and metformin. Gliclazide helps stimulate insulin production, while metformin improves insulin sensitivity, thereby reducing blood sugar levels.

How should I take Diamicron Xr Mex 30/500 Tablet 15?

Take this medication with your evening meal or as directed by your doctor. Always follow the prescribed dosage and instructions provided by your healthcare provider.

Can I take Diamicron Xr Mex 30/500 Tablet 15 if I'm pregnant?

No, Diamicron Xr Mex 30/500 Tablet 15 is not recommended during pregnancy. Consult your doctor for safer alternatives.

Are there any side effects of Diamicron Xr Mex 30/500 Tablet 15?

Yes, common side effects may include hypoglycaemia, nausea, headache, and diarrhoea. If these persist or worsen, contact your doctor.

Can I drink alcohol while taking Diamicron Xr Mex 30/500 Tablet 15?

It is advised to avoid alcohol as it may increase the risk of hypoglycaemia and lactic acidosis, both of which are serious side effects of this medication.

What should I do if I overdose on Diamicron Xr Mex 30/500 Tablet 15?

In case of an overdose, seek immediate medical assistance. Overdosing can lead to severe hypoglycaemia and lactic acidosis, both of which are potentially life-threatening conditions.

Last Updated On 11 Sep. 2026 | 11:43AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 10 years

PhD in Chemistry

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 11 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

Parinee Crescenzo, Floor No. 1703, Plot No. C38 & 39, 17th Floor B Wing, behind MCA, G Block BKC, Bandra Kurla Complex, Bandra East, Mumbai, Maharashtra 400051

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Gliclazide 80mg and Metformin 500mg. (N.d.). Fda.Gov. Retrieved November 8, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
GLUCOPHAGE® (metformin hydrochloride) Tablets. (N.d.). Fda.Gov. Retrieved November 8, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
Panacea Biotec Limited. (2019). PRODUCT MONOGRAPH GLIZID-M gliclazide 80mg and Metformin 500mg. https://media.panaceabiotec.com/documents/2019/7/27/ProductMonograph-GlizidM-GliclazideplusMetformin.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

Telephone:09240250346

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