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Dapamac Trio 1000mg Tablet 10 is used to manage type 2 diabetes mellitus. The combination of Dapagliflozin, Metformin, and Sitagliptin effectively lowers blood glucose levels.
Consult your doctor for the correct dosage. Inform them about any pre-existing conditions or other medications. Continue taking the medicine for the full prescribed duration for optimal results.
Dapamac Trio 1000mg Tablet 10 is used to manage Type 2 diabetes and improve blood sugar control. It enhances glycemic management in adults, especially when dual therapy is not enough, and helps regulate blood sugar levels alongside diet and exercise.
Swallow the whole tablet with water without chewing or crushing it.
Avoid breaking, crushing or chewing the tablet
Never exceed the recommended dose by your doctor
It is crucial to stop taking this medicine without speaking to your doctor
Dapamac Trio 1000mg Tablet 10 is taken orally.
Dapamac Trio 1000mg Tablet 10 may cause female genital mycotic infections, nasopharyngitis, urinary tract infections, diarrhoea, headache, nausea, and vomiting. If these side effects persist or worsen, consult your doctor.
Most side effects are temporary and generally harmless; resolved by discontinuing the use of Dapamac Trio 1000mg Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Try taking Dapamac Trio 1000mg Tablet 10 with food or milk to reduce the chance of diarrhoea.
If you have nausea, consider taking this medicine after meals to lessen this effect.
Dapamac Trio 1000mg Tablet 10 contains three active ingredients:
Dapagliflozin (10 mg): This sodium-glucose cotransporter-2 (SGLT2) inhibitor effectively reduces blood glucose levels by decreasing glucose reabsorption in the kidneys and increasing excretion through urine. This occurs regardless of the insulin levels in your body.
Metformin (1000 mg): Metformin belongs to a class of medications known as biguanides. It helps lower blood sugar levels by reducing the amount of glucose produced by the liver, decreasing glucose absorption in the intestines, and improving insulin sensitivity, which enhances glucose uptake and usage by the body cells.
Sitagliptin (100 mg): This dipeptidyl peptidase-4 (DPP-4) inhibitor works by slowing down the inactivation of incretin hormones, thus leading to an increase in insulin production from pancreatic beta cells and reducing glucagon secretion from pancreatic alpha cells. This process is dependent on glucose levels in your body.
If you are pregnant or planning to conceive, it is best to consult your doctor before starting Dapamac Trio 1000mg Tablet 10.
If you are breastfeeding, it is important to consult your doctor before taking this medication to manage your type 2 diabetes level.
Caution is advised when drinking alcohol while taking Dapamac Trio 1000mg Tablet 10. Alcohol can intensify some side effects and may also affect blood glucose levels. Consult your doctor.
If you have liver problems, it is crucial to discuss them with your doctor before starting the Dapamac Trio 1000mg Tablet 10, as it can further aggravate your condition.
Dapamac Trio 1000mg Tablet 10 is contraindicated in severe renal impairment, end-stage renal disease or if you are on dialysis. If you have less severe kidney problems, consult your doctor before using this medicine.
Dapamac Trio 1000mg Tablet 10 doesn't generally affect your ability to drive or operate machinery. However, if you experience any side effects like dizziness or fatigue that could impair these activities, avoid doing them until you are feeling better.
If you have a history of serious allergic reactions to any ingredients in Dapamac Trio 1000mg Tablet 10, this medicine should not be used. Inform your doctor about any allergies before starting a new medication.
It is always advisable to consult your doctor before giving any medicine to a child.
Older patients should take Dapamac Trio 1000mg Tablet 10 under medical supervision. They may be more susceptible to side effects and may have liver or kidney issues. Your doctor will guide you based on your health status.
Dapamac Trio 1000mg Tablet 10 interacts with the following medicines:
Thiazide Diuretics: Medicines like hydrochlorothiazide or bendroflumethiazide, when taken with Dapamac Trio 1000mg Tablet 10, may increase the risk of dehydration and low blood pressure.
Loop Diuretics: Medications such as furosemide or bumetanide may interact with Dapamac Trio 1000mg Tablet 10, potentially increasing the risk of lactic acidosis.
Carbonic Anhydrase Inhibitors: If you are taking medications like acetazolamide or methazolamide, the risk of lactic acidosis could be increased when combined with Dapamac Trio 1000mg Tablet 10.
Specific food interactions with Dapamac Trio 1000mg Tablet 10 have not been reported. However, it is always good to maintain a balanced diet when managing your diabetes.
Dapamac Trio 1000mg Tablet 10 interacts with the following diseases:
Severe Renal Impairment: Dapamac Trio 1000mg Tablet 10 is not recommended for individuals with severe renal impairment or those undergoing dialysis due to its metformin component.
Hepatic Impairment: People suffering from liver diseases should avoid Dapamac Trio 1000mg Tablet 10 due to potential risks associated with metformin therapy.
The daily dosage of Dapamac Trio 1000mg Tablet 10 is decided by your doctor, based on factors such as your health condition and response to the medicine. Never alter the prescribed dose without discussing it with your doctor.
In case of an accidental overdose of Dapamac Trio 1000mg Tablet 10, you may experience symptoms like nausea and discomfort. It's crucial not to panic but to inform your doctor about the situation so they can provide guidance.
If you miss a dose of Dapamac Trio 1000mg Tablet 10, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Increasing your dose without your doctor's advice isn't recommended.
Keep your Dapamac Trio 1000mg Tablet 10 in a tightly sealed container.
Store it at room temperature, ideally below 30°C.
Protect your medicine from moisture and humidity to maintain its effectiveness.
Always ensure that this medicine is out of reach of children.
Use the medicine before the expiry date mentioned on the package.
Follow a diet low in sugar and high in fibre. This can help control your blood sugar levels more effectively.
Regular physical activity like walking or yoga can help improve insulin sensitivity, thus helping your body use the sugar present in your system better.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | SGLT2 Inhibitor, Biguanide, DPP-4 Inhibitor |
| Therapeutic Category | Antihyperglycemic |
Dapamac Trio 1000mg Tablet 10 is used to manage blood sugar levels in adults with type 2 diabetes, in combination with diet and exercise.
The medicine reduces blood glucose by decreasing its production and absorption, increasing its uptake and utilisation, and facilitating more insulin production.
No, Dapamac Trio 1000mg Tablet 10 is not recommended for managing type 1 diabetes or diabetic ketoacidosis. It is mainly for type 2 diabetes in adults.
You should take the tablet orally. The tablet should be swallowed whole without crushing or chewing.
Yes, it can cause side effects like genital infections, nasopharyngitis, urinary tract infections, diarrhoea, headache, nausea, and vomiting .
No, if you have severe renal impairment or end-stage renal disease or if you are on dialysis, you should not take this medicine due to the metformin component.
Always consult your doctor before taking Dapamac Trio 1000mg Tablet 10 if you are pregnant or breastfeeding.
Check out Editorial Policy
Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Merck Sharp & Dohme Corp. (2006). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021995s019lbl.pdf
Sahay, R. K., Giri, R., Shembalkar, J. V., Gupta, S. K., Mohan, B., Kurmi, P., Kumar, S. R., Sawardekar, V. M., Mishra, A., Murthy, L. S., Arya, V. V., Sonawane, A. R., Soni, P. N., Gofne, S. K., Karnawat, S. R., Rajurkar, M. N., Patel, P. M., Lakhwani, L. K., Mehta, S. C., & Joglekar, S. J. (2023). Fixed-Dose Combination of Dapagliflozin + Sitagliptin + Metformin in Patients with Type 2 Diabetes Poorly Controlled with Metformin: Phase 3, Randomized Comparison with Dual Combinations. Advances in Therapy, 40(7), 3227–3246. https://doi.org/10.1007/s12325-023-02523-z
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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