Combitide 250 Octacaps 30

Sun Pharma Laboratories Ltd.

Bottle of 30 Units

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MRP ~~₹483.75~~

₹416.03

₹16.12/Units

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Prescription required for this medicine

Store Below 25°C

Composition

Fluticasone Propionate (250 Mcg) + Salmeterol (50 Mcg)

COMBITIDE 250 OCTACAPS 30 is used for the long-term maintenance treatment of asthma and COPD in adults, to control symptoms, improve breathing and reduce the risk of flare-ups.

It is a combination medicine for inhalation containing salmeterol (50 mcg), a long-acting bronchodilator, and fluticasone propionate (250 mcg), an inhaled corticosteroid. Use it regularly as prescribed using the appropriate inhaler device. The capsule is for inhalation only and must not be swallowed.

Rinsing the mouth and gargling with water after each use helps prevent a fungal mouth infection (oral thrush) alongside this medicine.

Tell your doctor about any heart conditions or diabetes before starting, and about other medicines you take. Keep a short-acting reliever inhaler for sudden symptoms. Report a sudden worsening in breathing after using this inhaler.

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COMBITIDE 250 OCTACAPS 30 is used for the long-term maintenance treatment of asthma and COPD in adults, to control symptoms and reduce exacerbations.

Uses of COMBITIDE 250 OCTACAPS 30 are:

Asthma Maintenance: Helps control and maintain asthma in adults needing combination therapy.
COPD Maintenance: Helps manage COPD symptoms and reduce flare-ups.
Long-Term Control: Provides sustained control of airway inflammation and obstruction.

This medicine is meant for inhalation only using a suitable device.
Avoid swallowing the capsules.
After each use, rinse your mouth with water to prevent oral fungal infection.
Always consult your doctor for specific advice on using this medication.

COMBITIDE 250 OCTACAPS 30 is administered through inhalation.

COMBITIDE 250 OCTACAPS 30 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Seronixt F 250 Capsule:

Respiratory: Throat irritation, hoarseness and cough.
Neurological: Headache. Resting and keeping well hydrated can help with headaches.
Oral: Fungal mouth infection (oral thrush).

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of COMBITIDE 250 OCTACAPS 30. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Throat Irritation: Drinking plenty of fluids can also help keep your throat moist and alleviate discomfort.
Oral Candidiasis: Brush your teeth and rinse your mouth with water after using the inhaler to help prevent fungal infections.

COMBITIDE 250 OCTACAPS 30 contains two active ingredients:

Fluticasone Propionate (250 mcg): As an inhaled corticosteroid, fluticasone propionate reduces inflammation in the lungs. It works by binding to glucocorticoid receptors in your cells, suppressing inflammatory mediators and decreasing airway hyperresponsiveness.
Salmeterol (50 mcg): This long-acting beta2-adrenergic agonist relaxes the muscles around your airways by stimulating beta2-adrenergic receptors in the lungs. This helps keep your airways open and makes breathing easier.

Pregnancy

Caution is advised while taking COMBITIDE 250 OCTACAPS 30 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's advised to discuss with your doctor before starting COMBITIDE 250 OCTACAPS 30.

Alcohol

To be on the safe side, it's best to avoid alcohol while using this medicine.

Liver

Caution is advised while taking this medicine in case of mild to moderate liver impairment. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before using COMBITIDE 250 OCTACAPS 30 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

There's no known effect of COMBITIDE 250 OCTACAPS 30 that could impact your ability to drive or operate machinery. However, if you experience dizziness or other side effects that might affect your abilities, refrain from such activities and speak to your doctor.

Allergy

This medicine is contraindicated if you're allergic to fluticasone, salmeterol or any other ingredients in COMBITIDE 250 OCTACAPS 30. Let your doctor know about any previous allergic reactions.

Children

Caution is advised while giving COMBITIDE 250 OCTACAPS 30 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take COMBITIDE 250 OCTACAPS 30 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

COMBITIDE 250 OCTACAPS 30 interacts with the following medicines:

HIV Protease Inhibitors: If you are taking medicines like ritonavir for HIV, the interaction might increase the risk of side effects from COMBITIDE 250 OCTACAPS 30.
Antifungals: Medicines such as ketoconazole may interact with COMBITIDE 250 OCTACAPS 30, potentially leading to increased side effects.
Beta-blockers: If you're on beta-blockers such as atenolol or propranolol, they could reduce the effectiveness of COMBITIDE 250 OCTACAPS 30 breathing-improvement action.

Drug-Food Interactions

There are no specific food interactions known with COMBITIDE 250 OCTACAPS 30.

Drug-Disease Interactions

COMBITIDE 250 OCTACAPS 30 interacts with the following diseases:

Diabetes: The fluticasone in COMBITIDE 250 OCTACAPS 30 could affect blood sugar control. So, if you have diabetes, close monitoring of blood glucose levels is needed.
Glaucoma and Cataracts: This medicine may increase pressure in your eyes, potentially worsening these conditions. Regular eye check-ups are advisable.
Osteoporosis: Long-term use of inhaled corticosteroids like fluticasone can weaken bones. So, if you already have osteoporosis, this may exacerbate your condition.
Heart Problems: Salmeterol in this medicine may cause changes in heartbeat or palpitations. If you have a history of heart problems, caution is advised.

Daily Dose

Take the daily recommended dose of COMBITIDE 250 OCTACAPS 30 as instructed by your doctor. The dosage may vary depending on factors like the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

In case you accidentally inhale more than the prescribed amount, you may experience common symptoms such as headache or throat irritation. If these symptoms persist, inform your doctor.

Missed Dose

If you forget to administer a dose of COMBITIDE 250 OCTACAPS 30, do so as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store COMBITIDE 250 OCTACAPS 30 at a temperature below 30°C.
Keep the product away from direct sunlight and moisture, ensuring it remains in its original packaging until use.
For safety, keep the medicine out of reach and sight of children.
Always check the expiry date on the package and use the product before that date.

If you're managing asthma or chronic obstructive pulmonary disease (COPD) with COMBITIDE 250 OCTACAPS 30, try to avoid exposure to smoke, including second-hand smoke. Smoke can trigger symptoms and make your condition worse.
Regular exercise within your capacity can also be beneficial. It helps improve lung function by strengthening the breathing muscles. However, remember to consult your doctor before starting any new exercise regimen.

Fact Box

Dosage Forms Available	Octacap
Habit Forming	No
Ailment	Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Drug Category	Inhaled Corticosteroid, Long-Acting Beta2-Adrenergic Agonist
Therapeutic Category	Anti-Asthmatic, Bronchodilator

What is COMBITIDE 250 OCTACAPS 30 used for?

COMBITIDE 250 OCTACAPS 30 is used to manage symptoms of obstructive airway diseases like asthma and chronic obstructive pulmonary disease (COPD).

How does COMBITIDE 250 OCTACAPS 30 work?

The medicine contains two components: Fluticasone reduces swelling in the lungs, and salmeterol relaxes muscles around the airways, helping you breathe easier.

Can COMBITIDE 250 OCTACAPS 30 be used for sudden asthma attacks?

No, it's a long-term maintenance medication. For sudden asthma symptoms, you should use a quick-relief inhaler instead.

How should I use COMBITIDE 250 OCTACAPS 30?

Inhale this medicine as advised by your doctor.

What should I do if I miss a dose of COMBITIDE 250 OCTACAPS 30?

If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed one and continue your regular schedule.

Can I stop using COMBITIDE 250 OCTACAPS 30 once my symptoms improve?

No, discontinuing abruptly can worsen your condition. Always consult your doctor before making any changes to your medication regimen.

Is COMBITIDE 250 OCTACAPS 30 addictive?

No, this medicine is not addictive. However, do not exceed the recommended usage without consulting your doctor.

Last Updated On 30 Jun. 2026 | 5:52PM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 9 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 10 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

Expiry on or after: December 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

ADVAIR DISKUS® 100/50 (fluticasone propionate 100 mcg and
salmeterol 50 mcg inhalation powder).(N.d.). Fda.Gov. Retrieved August 29, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021077s029lbl.pdf
ADVAIR HFA (fluticasone propionate and salmeterol inhalation aerosol).(N.d.). Fda.Gov. Retrieved August 29, 2024, from
https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021254s036lbl.pdf
DailyMed - FLUTICASONE PROPIONATE AND SALMETEROL powder, metered. (n.d.). Nih.Gov. Retrieved August 29, 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=77269609-fb89-47c7-97cc-22e0183e91ae
Fluticasone and Salmeterol Oral Inhalation. (n.d.). Medlineplus.Gov. Retrieved August 29, 2024, from
https://medlineplus.gov/druginfo/meds/a699063.html
Salmeterol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00938
Fluticasone propionate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00588

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Registered Office Address

Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

Grievance Officer

Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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