Cizaspa Sr Capsule 10

Lupin Ltd

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MRP ~~₹190.15~~

₹152.12

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Composition

Mebeverine (200 Mg)

Cizaspa-SR Capsule is primarily used to manage symptoms of irritable bowel syndrome (IBS). This medicine falls under the category of antispasmodic agents.

In addition to managing IBS, this medicine can also help alleviate associated discomforts such as abdominal pain, cramps, bloating, and irregular bowel movements. It is particularly effective in controlling these symptoms and helping you lead a more comfortable life.

Before starting this medication, it's crucial to consult your doctor who will guide you on the correct dosage and frequency. Make sure to inform your doctor about any pre-existing conditions or current medications you're taking. If you experience any side effects while on this medicine, notify your doctor promptly. Remember, for optimal results, continue taking the medicine for the entire duration prescribed by your doctor.

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Cizaspa-SR Capsule is commonly used for:

Management of irritable bowel syndrome (IBS)
Reduction of abdominal pain associated with IBS
Relief from cramping due to IBS
Alleviation of bloating and gas symptoms linked with IBS
Helping with irregular bowel movements caused by IBS

To get the most benefit from Cizaspa-SR Capsule, follow these guidelines:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Cizaspa-SR Capsule is taken orally.

Taking Cizaspa-SR Capsule may lead to the following side effects:

Nausea
Vomiting
Dizziness
Headache
Dry mouth
Constipation
Skin rash or itching

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Cizaspa-SR Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a couple of tips to manage common side effects:

Nausea: Try taking Cizaspa-SR Capsule with food or milk.
Constipation: Consider taking this medicine with plenty of water, which can help soften your stools.

Cizaspa-SR Capsule contains Mebeverine (200 MG) as its active ingredient. Here's how it works:

Blocks Calcium Channels: Mebeverine acts on calcium channels present in the smooth muscle cells of your gut, blocking them. This process prevents the influx of calcium ions required for muscle contractions.
Muscarinic Receptor Inhibition: Mebeverine inhibits muscarinic receptors on the gut muscles, further reducing muscle spasms.
Direct Relaxation Effect: In addition to inhibiting calcium channels and muscarinic receptors, mebeverine has a direct relaxant effect on intestinal smooth muscles. This dual action helps reduce abdominal pain and cramps associated with IBS.
Normalizes Bowel Movements: By controlling irregular contractions (spasms) of gut muscles, Mebeverine helps normalise bowel movements in individuals suffering from IBS.

Pregnancy

Caution is advised while taking Cizaspa-SR Capsule if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

You should consult your doctor before using this medicine while breastfeeding.

Alcohol

It's always wise to discuss your drinking habits with your doctor before starting any new medication.

Liver

If you have liver health issues, caution is recommended while taking Cizaspa-SR Capsule. Your dosage might need to be adjusted based on your health condition.

Kidney

People with kidney problems should be cautious while using Cizaspa-SR Capsule. It's a good idea to consult your doctor before starting this medication.

Using Machines & Driving

Cizaspa-SR Capsule can cause side effects like dizziness or blurred vision. So, you should avoid driving or operating heavy machinery until you know how the medicine affects you.

Allergy

If you're allergic to Mebeverine or any other ingredients of Cizaspa-SR Capsule, do not take this medicine. Always inform your doctor about any allergies you have.

Children

Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should use Cizaspa-SR Capsule under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age.

Drug-Drug Interactions

Cizaspa-SR Capsule interacts with the following medicines:

Antihistamines: Medicines like cetirizine and loratadine may interact with Cizaspa-SR Capsule, potentially increasing the risk of side effects such as dry mouth and dizziness.
Antidepressants: Tricyclic antidepressants (TCAs) like amitriptyline and imipramine, and monoamine oxidase inhibitors (MAOIs) like phenelzine and isocarboxazid can increase the antispasmodic effect of this medicine, leading to enhanced relief from abdominal cramps but also a higher risk of side effects.
Parkinson's Disease Medications: Medicines like levodopa may interact with Cizaspa-SR Capsule, potentially leading to altered medicinal effects or increased risk of side effects such as dry mouth and constipation.
Antipsychotics: Concomitant use of medicines like risperidone or haloperidol with Cizaspa-SR Capsule may increase the risk of adverse effects like dizziness or constipation.

Drug-Food Interactions

There are no food interactions with Cizaspa-SR Capsule.

Drug-Disease Interactions

Cizaspa-SR Capsule interacts with the following diseases:

Paralytic Ileus: This condition, which involves a lack of intestinal movement, could be exacerbated by Cizaspa-SR Capsule due to its muscle relaxant effect on the gut.
Intestinal Obstruction: Use of this medicine in cases of blocked bowel could worsen the patient's condition.
Severe Ulcerative Colitis: As this inflammatory bowel disease involves frequent diarrhoea and abdominal pain, the antispasmodic action of Cizaspa-SR Capsule could potentially increase these symptoms.

Daily Dose

The daily dosage of Cizaspa-SR Capsule should be as prescribed by your doctor. Your doctor may adjust the dosage based on your individual response to the medication and severity of the condition. Do not exceed the prescribed dosage without consulting your doctor.

Over Dose

Overdosing on Cizaspa-SR Capsule can lead to symptoms like feeling drowsy, confused, experiencing dry mouth, nausea, vomiting or a faster heartbeat. If you suspect an overdose, it's important that you inform your doctor right away.

Missed Dose

In case you miss a dose of Cizaspa-SR Capsule, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Cizaspa-SR Capsule at room temperature, ideally between 15 and 30 degrees Celsius.
Keep the medicine away from excess light and moisture to maintain its efficacy.
Always ensure the medicine is out of the reach of children.
Remember to use Cizaspa-SR Capsule before its expiry date for the best results.

Ensuring a balanced diet rich in fibre can help manage symptoms of irritable bowel syndrome (IBS). Include whole grains, fruits, and vegetables in your meals.
Regular physical activity can also help reduce IBS symptoms. Try to incorporate moderate exercise, like walking or cycling, into your daily routine.

Fact Box

Available Dosage Types	SR Capsule
Habit Forming	No
Ailment	Irritable Bowel Syndrome, Abdominal Cramps
Drug Category	Calcium Channel Blocker
Therapeutic Category	Antispasmodic

What is Cizaspa-SR Capsule used to manage?

Cizaspa-SR Capsule is used to manage symptoms of irritable bowel syndrome (IBS) like abdominal pain, cramps, bloating, and irregular bowel movements.

How does the medicine in Cizaspa-SR Capsule work?

The active ingredient, Mebeverine, works by relaxing the muscles in your gut, reducing spasms and relieving IBS symptoms like abdominal pain and cramps.

Can I take Cizaspa-SR Capsule for a long time?

Yes, Cizaspa-SR Capsule is generally safe for long-term use when taken as directed. Always consult your doctor about the duration of medication.

Can I take Cizaspa-SR Capsule with other IBS medicines?

You should consult your doctor before taking Cizaspa-SR Capsule with other IBS medicines to avoid potential interactions.

I missed a dose of Cizaspa-SR Capsule, what should I do?

If you miss a dose, take it as soon as you remember. If it's nearly time for the next one, skip the missed dose and continue as normal.

Is Cizaspa-SR Capsule gluten-free?

Yes, Cizaspa-SR capsules do not contain gluten. Nonetheless, it's always best to check with your doctor if you have celiac disease or gluten sensitivity.

How soon can I expect to see improvements after starting on Cizaspa-SR Capsule?

It might take 1-2 weeks before you start noticing an improvement in your symptoms and up to 4 weeks for full benefits.

Last Updated On 13 May. 2025 | 9:49AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead & Reviewer | 6 years

MBBS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MeBeverine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB12554
Arrotex Pharmaceuticals. (n.d.). MEBEVERINE (Arrotex Pharmaceuticals) datasheet. https://www.medsafe.govt.nz/profs/datasheet/m/mebeverinetab.pdf
Mebeverine hydrochloride. (2021). Package Leaflet: Information for the patient Mebeverine 135 mg film-coated tablets. https://www.medicines.org.uk/emc/files/pil.2315.pdf
Unknown. (2021). Package leaflet: Information for the patient Mebeverine hydrochloride 135 mg Film-coated Tablets. https://www.hpra.ie/img/uploaded/swedocuments/faee725e-6d31-4b79-95ba-0bbd849b5170.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.

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