Mebeverine
Uses of Mebeverine
Mebeverine is used to relieve the symptoms of irritable bowel syndrome (IBS) and other conditions involving painful intestinal spasms.
Mebeverine is commonly used for:
• Irritable bowel syndrome (IBS): Relieves abdominal cramping, pain, bloating, and bowel habit changes associated with IBS, including both constipation-predominant and diarrhoea-predominant types.
• Spastic colon: Reduces painful involuntary contractions of the colon that cause abdominal discomfort and irregular bowel movements.
• Mucous colitis: Relieves symptoms associated with intestinal spasm, such as abdominal pain and discomfort.
• Chronic irritable colon: Provides symptomatic relief of abdominal pain and intestinal spasms.
• Intestinal spasm associated with other conditions: Used for abdominal cramping related to other gastrointestinal conditions where muscle spasm is a contributing factor.
Side effects of Mebeverine
Nausea
Headache
Dizziness
Insomnia
Allergic skin reactions
How Mebeverine works
Mebeverine works by directly relaxing the smooth muscle in the walls of the intestines, reducing painful spasms without significantly affecting normal bowel movement patterns.
It is classified as a musculotropic antispasmodic, meaning it acts directly on the muscle tissue of the gut rather than on the nervous system.
Mebeverine relaxes intestinal smooth muscle through its direct action on the muscles of the gut:
- Relief of intestinal spasm: It relaxes the muscles of the intestine, helping to reduce painful spasms and cramping associated with irritable bowel syndrome (IBS).
- Reduction of abdominal pain and discomfort: By relieving intestinal muscle spasm, it helps reduce abdominal pain and other symptoms associated with IBS.
Unlike some other antispasmodics, Mebeverine's action is selective to the gut, meaning it generally does not cause the dry mouth, blurred vision, or urinary retention that can occur with medicines that block acetylcholine throughout the body. This makes it well tolerated for ongoing symptom management in IBS.
Certified content
Written By
BDS, MDS
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
- Mebeverine is available for oral administration via the following forms: immediate-release tablets, sustained-release capsules, and granules for oral suspension.
Age And Dose Restrictions
- Mebeverine is intended for use in adults and adolescents above 12 years of age. The suitable dose would be advised by the doctor.
Contraindications
- Mebeverine is contraindicated in individuals with a known hypersensitivity to Mebeverine or any of its components.
- Patients with porphyria, a group of rare genetic disorders that affect the nervous system, should not use this medicine.
Other Medications To Avoid With This Medicine
- Mebeverine may interact with antimuscarinic medicines (such as atropine and scopolamine), opioids (such as codeine and morphine), antifungals (like ketoconazole), and medications for tuberculosis (such as rifampicin).
Overdose And Missed Dose
- An overdose of Mebeverine may cause symptoms such as dizziness, agitation, and increased excitability of the central nervous system. If you suspect an overdose, contact your doctor or go to the nearest hospital immediately.
- If you miss a dose of Mebeverine, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for the missed one. Mebeverine is most effective when taken consistently before meals as recommended by your doctor.
Management Of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
- Drinking ample water can help ease dry mouth.
- Relaxation techniques like deep breathing exercises can help manage dizziness and insomnia.
Use In Driving And Operating Machinery
- Mebeverine may cause side effects such as dizziness or sleepiness. If you experience these after taking the medicine, avoid driving or operating heavy machinery until you feel well again.
Use In Pregnancy And Lactation
- Mebeverine should be used during pregnancy and lactation only if prescribed by your doctor.
Caution In Other Conditions
- Patients with significant bladder outflow obstruction, angle-closure glaucoma, and myasthenia gravis (weakness and rapid fatigue of voluntary muscles) should use this medicine carefully, as it may exacerbate these conditions.
Special Dietary And Lifestyle Recommendation
- Maintain a balanced diet with plenty of fruits, vegetables, and whole grains.
- Regular physical activity can help relieve stress and improve digestion.
- Limit intake of gas-producing foods like beans, broccoli, and cabbage, which may worsen IBS symptoms.
- Avoid food triggers, which can vary from person to person but may include dairy products, caffeine, and alcohol.
Frequently asked questions
Is Mebeverine a steroid?
No, Mebeverine is not a steroid. It belongs to the class of antispasmodic medications, specifically known as musculotropic antispasmodics.
Does Mebeverine have any effect on sleep?
Mebeverine has been reported to cause insomnia in some cases, but this side effect is relatively uncommon. Always consult your doctor if you experience unexpected or severe side effects.
Will Mebeverine affect fertility?
There is no evidence to suggest that Mebeverine affects fertility in men or women. However, if you have any concerns or experience any issues, you should discuss them with your doctor.
Is it safe to take Mebeverine daily?
Mebeverine should be taken in the dosage and duration as prescribed by your doctor and used according to their instructions.
How much time does Mebeverine take to work?
The exact time for Mebeverine to start working can vary between different individuals, but generally, it starts acting within a few hours of administration.
What is the best time to take Mebeverine?
The best time to take Mebeverine is approximately 20 minutes before meals, as advised by your doctor.
Is Mebeverine available over the counter, or do I need a prescription?
Mebeverine usually requires a prescription and is not typically available over the counter.
Mebeverine in other salts
List of medicines for Mebeverine
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