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CompositionOcabile 5 Tablet is used to manage primary biliary cirrhosis (PBC), a chronic autoimmune liver disease. It reduces liver inflammation and fibrosis, slowing disease progression and improving liver function.
Take this medication as directed by your doctor. Discuss any pre-existing conditions or ongoing medications with your doctor before starting treatment. Report any side effects promptly and continue the medicine for the prescribed duration.
Ocabile 5 Tablet is used to manage primary biliary cirrhosis, a chronic autoimmune liver disease. It helps slow liver damage progression, improves liver function, and enhances bile flow, reducing inflammation and fibrosis in patients with this liver condition.
While taking Ocabile 5 Tablet, follow these instructions:
Ocabile 5 Tablet is taken orally.
Ocabile 5 Tablet may cause side effects such as itching, fatigue, skin rash, throat pain, dizziness, constipation, joint pain, abdominal discomfort, eczema, thyroid disorders, peripheral oedema (swelling in limbs), and palpitations. If these side effects persist or worsen, consult your doctor.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Ocabile 5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
To manage some common side effects:
Itching: Try taking Ocabile 5 Tablet with food to lessen this effect.
Abdominal discomfort: Consider taking this medicine at night if it causes you discomfort during the day.
Ocabile 5 Tablet contains obeticholic acid (5 mg), which works on your body as follows:
Activates FXR: Obeticholic acid works by activating the Farnesoid X Receptor (FXR) in your body. FXR is a protein that plays a crucial role in controlling bile acid levels in your body.
Decreases Bile Acid Synthesis: By activating FXR, obeticholic acid reduces the production of bile acids.
Increases Bile Flow: This activation also promotes better bile flow, preventing it from getting trapped in the liver.
Reduces Liver Inflammation and Fibrosis: The improved bile flow and reduced bile acid synthesis lead to a decrease in liver inflammation and fibrosis, improving overall liver function.
Caution is advised while taking Ocabile 5 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.
It is recommended to consult your doctor before taking this medicine if you are breastfeeding.
While on Ocabile 5 Tablet, it's advisable to limit the consumption of alcohol as it could potentially exacerbate liver issues. Please discuss this with your doctor.
Close monitoring of liver function is essential while you are on Ocabile 5 Tablet, especially if you have other liver conditions apart from PBC. Your doctor will guide you based on your health status.
If you have a history of kidney problems, caution is advised before starting Ocabile 5 Tablet. It's a good idea to consult your doctor first.
There are no specific precautions regarding operating machines or driving while on the Ocabile 5 Tablet. However, be aware that some side effects, like dizziness, may affect your ability to concentrate.
Before starting Ocabile 5 Tablet, inform your doctor about any allergies you may have, as this medicine may contain inactive ingredients that can cause allergic reactions or other problems.
Ocabile 5 Tablet should only be given to children under medical supervision and consultation. It's always important to speak with your doctor first.
Older patients should take Ocabile 5 Tablet under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your overall health status.
Ocabile 5 Tablet interacts with the following medicines:
Bile acid sequestering agents: Medicines like cholestyramine and colestipol may interact with Ocabile 5 Tablet. Take this medicine at least four hours before or after these medications.
Anticoagulants: The effect of anticoagulants like warfarin might be altered when taken alongside Ocabile 5 Tablet.
Immunosuppressants: Cyclosporine and other immunosuppressant medicines may interact with Ocabile 5 Tablet, potentially leading to altered medication effects.
There are no known specific food interactions with Ocabile 5 Tablet.
Ocabile 5 Tablet interacts with the following diseases:
Liver disease: If you have any liver problems other than primary biliary cirrhosis (PBC), be sure to inform your doctor, as this medication could exacerbate your condition.
Thyroid disorders: Ocabile 5 Tablet may interact with certain thyroid conditions, possibly affecting the effectiveness of your thyroid medication.
Your doctor will prescribe the precise daily dosage of Ocabile 5 Tablet, considering factors like your condition's severity and your response to treatment. It's crucial to follow this prescribed dosage and not exceed it without consulting your doctor.
In the unlikely event of an overdose of Ocabile 5 Tablet, you might experience intensified side effects like severe itching, fatigue, or abdominal discomfort. If these symptoms persist or worsen, inform your doctor.
If you've missed a dose of Ocabile 5 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.
Store Ocabile 5 Tablet at room temperature between 20°C and 25°C.
Keep the medicine in its original packaging, ensuring it's tightly sealed to protect from moisture.
Place Ocabile 5 Tablet in a safe location, out of reach of children and pets.
Always check the expiration date on the label before use; do not use the medicine past this date.
Since Ocabile 5 Tablet is used to manage primary biliary cirrhosis (PBC), maintaining a well-balanced, nutritious diet can be beneficial. This should include plenty of fruits, vegetables, lean proteins, and whole grains while limiting processed foods.
Regularly engage in low-intensity physical activities like walking, yoga, or light stretching exercises. This can help boost overall health and vitality while managing PBC symptoms. Always consult your doctor before starting any new exercise routine.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Primary Biliary Cirrhosis |
| Drug Category | Farnesoid X Receptor Agonist |
| Therapeutic Category | Liver Disease Management |
It's used to manage primary biliary cirrhosis, a chronic liver disease affecting the small bile ducts.
It's orally administered, usually once daily. Always follow your doctor's instructions and take it at the same time each day.
Yes, you can take Ocabile 5 Tablet with or without food.
Take it as soon as you remember. However, skip it if it's nearly time for the next dose.
Possible side effects include itching, fatigue, skin rash, throat pain, and dizziness, among others.
No, it may harm an unborn baby. Use effective contraception while taking this medicine.
This medicine isn't a cure, but it helps control the disease, relieve symptoms, and slow down liver damage.
Check out Editorial Policy
Intercept Pharmaceuticals. (2016). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/207999s008lbl.pdf
Obeticholic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB05990
Obeticholic acid: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a616033.html
Nevens, F., Andreone, P., Mazzella, G., Strasser, S. I., Bowlus, C., Invernizzi, P., Drenth, J. P., Pockros, P. J., Regula, J., Beuers, U., Trauner, M., Jones, D. E., Floreani, A., Hohenester, S., Luketic, V., Shiffman, M., Van Erpecum, K. J., Vargas, V., Vincent, C., . . . Shapiro, D. (2016). A Placebo-Controlled Trial of obeticholic acid in primary biliary cholangitis. New England Journal of Medicine/the New England Journal of Medicine, 375(7), 631–643. https://doi.org/10.1056/nejmoa1509840
Kowdley, K. V., Luketic, V., Chapman, R., Hirschfield, G. M., Poupon, R., Schramm, C., Vincent, C., Rust, C., Parés, A., Mason, A., Marschall, H., Shapiro, D., Adorini, L., Sciacca, C., Beecher‐Jones, T., Böhm, O., Pencek, R., & Jones, D. (2018). A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis. Hepatology, 67(5), 1890–1902. https://doi.org/10.1002/hep.29569
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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