Tripin Om 40 Tablet 10

Lupin Ltd

Strip of 10 Units

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MRP ~~₹261.25~~

₹222.06

₹26.12/Units

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Composition

Amlodipine (5 Mg) + Hydrochlorothiazide (12.5 Mg) + Olmesartan Medoxomil (40 Mg)

Tripin OM 40 Tablet is primarily used to manage high blood pressure in adults. It's a combination medicine that belongs to the classes of calcium channel blockers, thiazide diuretics, and angiotensin II receptor blockers.

In addition to its main use for hypertension, this medication is also beneficial when a triple combination therapy is needed, especially for patients whose blood pressure isn't adequately controlled by dual combination therapy. The convenience of this tablet formulation simplifies the treatment regimen and potentially improves patient adherence.

This medicine should be taken orally as directed by your doctor. It's important that you let your doctor know about any pre-existing conditions or ongoing medications before you start taking this medicine. If you experience any side effects while on this medication, inform your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Tripin OM 40 Tablet is used for the following:

Management of hypertension in adults
Control of high blood pressure when dual combination therapy is insufficient
Reducing peripheral vascular resistance for blood pressure control
Decreasing cardiac output to help manage high blood pressure
Lowering blood pressure by reducing the volume of blood

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
You can take this medicine with or without food.
Always adhere to the recommended dosage by your doctor.
If you have any doubts regarding its intake, consult your doctor.

Tripin OM 40 Tablet is taken orally.

Tripin OM 40 Tablet may have the following common side effects:

Dizziness
Headache
Oedema: This refers to swelling caused by excess fluid trapped in your body's tissues.
Fatigue
Gastrointestinal disturbances

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Tripin OM 40 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dizziness: Try taking Tripin OM 40 Tablet at bedtime to manage this effect.
Gastrointestinal disturbances: Consider having this medicine with meals to lessen stomach discomfort.

Tripin OM 40 Tablet works through a blend of three active ingredients:

Amlodipine (5 mg): As a calcium channel blocker, it inhibits the movement of calcium into vascular smooth muscle and cardiac muscle cells. This action causes these muscles to relax (a process called vasodilation), reducing peripheral vascular resistance and thereby lowering blood pressure.
Hydrochlorothiazide (12.5 mg): This ingredient is a thiazide diuretic which increases the excretion of sodium, chloride, and water from the kidneys. By reducing the volume of blood that needs to be pumped around the body, it decreases cardiac output and helps lower blood pressure.
Olmesartan Medoxomil (40 mg): This angiotensin II receptor blocker selectively prevents angiotensin II from binding to its receptor in vascular smooth muscle and adrenal gland cells. This inhibition relaxes blood vessels (vasodilation) and reduces peripheral resistance, which lowers blood pressure.

Pregnancy

Tripin OM 40 Tablet is not recommended if you are pregnant, especially during the second and third trimesters. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, avoid using Tripin OM 40 Tablet as it may pass into breast milk. Discuss with your doctor to understand potential risks and benefits.

Alcohol

Alcohol may enhance the blood pressure-lowering effect of this medicine. Consult your doctor for guidance.

Liver

Caution is advised while taking Tripin OM 40 Tablet if you have mild to moderate liver problems. This medicine is not recommended for severe liver diseases. Discuss with your doctor if you have liver health issues before starting this medication.

Kidney

If you have kidney health issues, be cautious while taking Tripin OM 40 Tablet. It's important to consult your doctor before taking this medicine.

Using Machines & Driving

You may experience dizziness or lightheadedness while on this medication, especially in the initial phase of treatment. Avoid driving or operating machinery until you know how this medicine affects you.

Allergy

Do not take Tripin OM 40 Tablet if you are allergic to any of its components. If you have a history of angioedema or other allergies, discuss them with your doctor before starting this medicine.

Children

Tripin OM 40 Tablet is meant for use by adults only and should not be given to children under 18 years of age.

Older Patients

Older patients should take Tripin OM 40 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients above 70 years of age who might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Tripin OM 40 Tablet can interact with the following medicines:

Potassium supplements and potassium-sparing diuretics: Medications like spironolactone and amiloride can interact with Tripin OM 40 Tablet, potentially increasing your blood potassium levels (hyperkalaemia).
Mood stabilisers: Tripin OM 40 Tablet may interact with lithium, leading to an increase in lithium levels and possible toxicity.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): When taken with Tripin OM 40 Tablet, NSAIDs like ibuprofen and naproxen can reduce the blood pressure-lowering effects of the tablet and increase the risk of kidney dysfunction.
Antidiabetic agents: The diuretic effect of hydrochlorothiazide in Tripin OM 40 Tablet may affect blood glucose levels, potentially reducing the effectiveness of medicines like metformin and insulin.

Drug-Food Interactions

High-potassium foods: Foods rich in potassium such as bananas, oranges, and spinach should be consumed in moderation due to the risk of hyperkalemia (high blood potassium levels).

Drug-Disease Interactions

Tripin OM 40 Tablet can interact with the following diseases:

Liver disease: People with severe liver disease should be cautious as Tripin OM 40 Tablet could exacerbate their condition.
Renal impairment: Patients with kidney disease might experience an increase in potassium levels due to this medicine. Regular monitoring of potassium levels is essential for these patients.
Diabetes: As Tripin OM 40 Tablet could impact blood sugar control, it is important to monitor glucose levels closely when on this medication.

Daily Dose

The daily dose of Tripin OM 40 Tablet should be taken as directed by your doctor. The dosage may vary depending on factors such as the severity of your condition and how you respond to the medicine. It's crucial to stick to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Tripin OM 40 Tablet, you might experience symptoms like dizziness or a headache. If these symptoms persist or worsen, inform your doctor promptly.

Missed Dose

If you forget to take your regular dose of Tripin OM 40 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and follow your usual dosing schedule. Never increase your dosage without consulting your doctor.

Store Tripin OM 40 Tablet at room temperature below 30°C.
Keep it in a dry place, away from direct light and moisture.
Ensure the medicine is kept out of the reach of children.
Always check the expiry date before taking the medicine.

Maintain a low-salt, low-fat diet: High blood pressure can be managed by reducing your intake of salt and unhealthy fats. This helps control your blood pressure levels, aiding the effectiveness of Tripin OM 40 Tablet.
Regular Exercise: Engage in moderate physical activity for at least 30 minutes each day. This helps reduce high blood pressure, improving your overall cardiovascular health.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension
Drug Category	Calcium Channel Blocker, Thiazide Diuretic, Angiotensin II Receptor Blocker
Therapeutic Category	Antihypertensive

What is Tripin OM 40 Tablet used for?

It is used to manage hypertension (high blood pressure) in adults.

How does Tripin OM 40 Tablet work?

It combines three medicines that each lower blood pressure in different ways, resulting in comprehensive control.

Can I take Tripin OM 40 Tablet with or without food?

Yes, this medicine can be taken with or without food as advised by your doctor.

What are the common side effects of Tripin OM 40 Tablet?

Side effects may include dizziness, headache, swelling, tiredness, and digestive discomfort.

Is Tripin OM 40 Tablet safe for pregnant or nursing women?

Pregnant women, especially in their second and third trimesters, and nursing mothers should avoid this medicine.

Can I drive or operate machinery after taking Tripin OM 40 Tablet?

If you feel dizzy or lightheaded after taking the medicine, avoid driving or operating machinery.

How should I store Tripin OM 40 Tablet?

Store it at room temperature, away from light and moisture, out of reach of children and pets.

Last Updated On 13 May. 2025 | 10:44AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2010). https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/200175s011lbl.pdf
Pfizer. (1987). NORVASC [Prescribing Information]. In NORVASC (pp. 1–7). https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf
Reference ID: 4659169. (n.d.). MICROZIDE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020504s026lbl.pdf
Daiichi Sankyo, Inc. (2002). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021286s023lbl.pdf
Amlodipine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00381
Hydrochlorothiazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00999
Olmesartan: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00275

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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