Sildoease 4 D Capsule 10

Q: Is Sildoease-4 D Capsule an antibiotic?

No, Sildoease-4 D Capsule is not an antibiotic. It belongs to the group of medications called alpha-blockers. It is used to treat the symptoms of Benign prostatic hyperplasia or enlarged prostate in men who are aged above 50 years.

Q: How long can Sildoease-4 D Capsule be taken?

Sildoease-4 D Capsule should be taken for as long as a doctor prescribes it.

Q: Is Sildoease-4 D Capsule too hard on kidneys?

Yes. Sildoease-4 D Capsule should not be given to patients with severe kidney disease and also requires dose adjustment in patients with mild to moderate kidney disease.

Q: How long does Sildoease-4 D Capsule take to work?

Sildoease-4 D Capsule takes a few days to show its effect of relieving lower urinary tract symptoms due to Benign Prostatic Hyperplasia.

Q: Does Sildoease-4 D Capsule capsule cause retrograde ejaculation?

Yes, Sildoease-4 D Capsule causes the side effect of retrograde ejaculation, where the semen goes back into the urinary bladder instead of coming out. So on orgasm, the ejaculate has very little semen.

Q: What class of medication is Sildoease-4 D Capsule?

It belongs to the alpha-blockers group of medicines. It is used to treat the symptoms of enlarged prostate in men.

Q: Does Sildoease-4 D Capsule cause constipation?

No, Sildoease-4 D Capsule does not cause constipation. On the contrary, it can cause diarrhoea.

Q: What are the main contents of Sildoease-4 D Capsule?

The main constituents of Sildoease-4 D Capsule are Silodosin and Dutasteride. It is a combination medicine and belongs to the category of selective alpha-1 adrenergic receptor antagonists.

Q: What is the mode of the action of Sildoease-4 D Capsule?

The primary mechanism of Sildoease-4 D Capsule is by blocking alpha receptors present on the surface of the prostate, urinary bladder and urethra, thereby relaxing the smooth muscles of the bladder and prostate gland and enhancing the urine flow.

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MRP ~~₹175~~

₹87.33

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Composition

Dutasteride (0.5 Mg) + Silodosin (4 Mg)

Sildoease-4 D Capsule is used to manage the signs and symptoms of Benign prostatic hyperplasia (BPH) or enlarged prostate. It is a combination medicine and belongs to the category of selective alpha-1 adrenergic receptor antagonists.

It also provides relief from lower urinary tract symptoms like dribbling, urinary retention, etc, associated with Benign Prostatic hyperplasia, which helps improve the quality of life of such patients. It does not cure the disease but provides efficient symptomatic relief.

Inform your doctor about any pre-existing diseases, allergies and the medicines you take. Your doctor will carefully review and decide regarding the dosage and frequency of use of this medicine. In case of any persistent or worsening side effects, seek medical advice.

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Sildoease-4 D Capsule is used in the management of:

Benign Prostatic Hyperplasia: It provides symptomatic relief in such patients by relieving lower urinary tract symptoms such as difficulty in urination, dribbling of urine, weak stream of urine, and incomplete emptying of the bladder.

Take this medicine with a glass of water.
Swallow the capsule as a whole, do not crush or chew it.
This medication should be taken preferably with meals.
This medicine is recommended to be taken at a fixed daily time.

Sildoease-4 D Capsule should be taken orally.

The side effects of Sildoease-4 D Capsule include:

Diarrhoea
Dizziness
Orthostatic Hypotension/Postural Hypotension (Low blood pressure associated with posture, which occurs when the patient stands after sitting or lying for a while)
Stuffy nose or runny nose
Headache
Nasopharyngitis (Inflammation of the Nose and Pharynx)

Managing the Side Effects:

Most of the side effects are temporary and harmless and can be resolved by discontinuing the capsule. These may not require medical attention. To combat gastrointestinal side effects, take this capsule with food. If you experience any severe or persistent side effects due to this capsule, consult your doctor.

Sildoease-4 D Capsule contains the following components:

Silodosin (4 mg): It is an alpha-adrenergic antagonist that works by blocking the alpha 1A type of adrenoceptors located in the prostate gland, urethra and urinary bladder. It leads to the relaxation of smooth muscles in these locations, thus easing urinary flow.
Dutasteride (0.5 mg): It is a 5-alpha reductase inhibitor that works by inhibition of both type 1 and 2 of 5-alpha reductase. It is responsible for the conversion of testosterone to 5-alpha dihydrotestosterone. It is responsible for the initial development and subsequent enlargement of the prostate gland.

Pregnancy

Not applicable

Breastfeeding

Not applicable

Alcohol

Avoid alcohol consumption while on this medicine as it can aggravate the orthostatic hypotension caused by this medicine.

Liver

Sildoease-4 D Capsule should not be given to patients with severe liver disease or impairment. Dose adjustment is needed for mild to moderate liver disease after consultation with a doctor.

Kidney

Sildoease-4 D Capsule should not be given to patients with severe kidney disease or impairment. Dose adjustment is needed for mild to moderate kidney disease after consultation with a doctor.

Using Machines & Driving

Sildoease-4 D Capsule can cause postural hypotension and dizziness, which can impair driving and machine operating capability. Refrain from such activities while you are taking this medication.

Allergy

If you are allergic to this medicine or any of its constituents, then do not take it.

Children

Sildoease-4 D Capsule is not indicated for use in paediatric patients (<18 years of age).

Older Patients

Sildoease-4 D Capsule is to be used with caution in elderly patients with liver or kidney disease as they usually need dose adjustment after consultation from a doctor.

Drug-Drug Interactions

Sildoease-4 D Capsule interacts with the following medicines:

Antifungals like itraconazole and ketoconazole should not be taken with this medicine as it may increase the effect of this medicine.
Blood pressure-lowering medicines like verapamil and diltiazem can aggravate Orthostatic Hypotension caused by this medicine.
Antivirals like ritonavir decrease the metabolism of this medicine and increase its effect and side effects.
Immune-suppressing medications like cyclosporine should not be given with Sildoease-4 D Capsule as it might increase the effect of this medicine.
Antibiotics like clarithromycin and erythromycin should not be used with this medicine as they can reduce the effectiveness of this medicine.
Erectile dysfunction medicines like tadalafil and sildenafil (PDE-5 inhibitors) increase the side effects of this capsule like orthostatic hypotension, dizziness, etc.

Drug-Food Interactions

Sildoease-4 D Capsule interacts with the following the foods:

High-fat or moderate-calorie meals: Consumption of these foods can reduce the plasma concentration of Sildoease-4 D Capsule and thus reduce its effect.

Drug-Disease Interactions

Sildoease-4 D Capsule interact with the following diseases:

Severe kidney diseases: It can be aggravate the disease.
Severe liver diseases: The capsule can be worsen the disease.

Daily Dose

The daily dose of this medicine should be taken as prescribed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you or someone else takes an excessive amount of this medicine by accident, inform your doctor immediately and follow his advice. The overdose symptoms of this medicine include dizziness, fainting, lightheadedness and blurred vision. Be vigilant and do not ignore these symptoms.

Missed Dose

If you forget to take this medicine, take it as soon as you remember. However, avoid repeating the dose.

Store Sildoease-4 D Capsule at room temperature (15-25ºC).
Protect Sildoease-4 D Capsule from light and moisture.
Keep it away from children and pets
Do not use this medicine after the expiry date has passed.

Reduce the intake of substances that increase diuresis like coffee, and alcohol.
Perform regular pelvic exercises for symptomatic relief.
In case of anticipated eye surgery for cataracts, or glaucoma, inform the doctor about your consumption of this medicine.
Get your PSA (Prostate-specific antigen) levels checked regularly to rule out the development of cancer in the Prostate gland as well as to document improvement in Benign Prostatic Hyperplasia.

Fact Box

Drug Category	Selective alpha-1 adrenergic receptor antagonist
Therapeutic Category	Urology
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Symptomatic relief from lower urinary tract symptoms in Benign prostatic hyperplasia

Is Sildoease-4 D Capsule an antibiotic?

No, Sildoease-4 D Capsule is not an antibiotic. It belongs to the group of medications called alpha-blockers. It is used to treat the symptoms of Benign prostatic hyperplasia or enlarged prostate in men who are aged above 50 years.

How long can Sildoease-4 D Capsule be taken?

Sildoease-4 D Capsule should be taken for as long as a doctor prescribes it.

Is Sildoease-4 D Capsule too hard on kidneys?

Yes. Sildoease-4 D Capsule should not be given to patients with severe kidney disease and also requires dose adjustment in patients with mild to moderate kidney disease.

How long does Sildoease-4 D Capsule take to work?

Sildoease-4 D Capsule takes a few days to show its effect of relieving lower urinary tract symptoms due to Benign Prostatic Hyperplasia.

Does Sildoease-4 D Capsule capsule cause retrograde ejaculation?

Yes, Sildoease-4 D Capsule causes the side effect of retrograde ejaculation, where the semen goes back into the urinary bladder instead of coming out. So on orgasm, the ejaculate has very little semen.

What class of medication is Sildoease-4 D Capsule?

It belongs to the alpha-blockers group of medicines. It is used to treat the symptoms of enlarged prostate in men.

Does Sildoease-4 D Capsule cause constipation?

No, Sildoease-4 D Capsule does not cause constipation. On the contrary, it can cause diarrhoea.

What are the main contents of Sildoease-4 D Capsule?

The main constituents of Sildoease-4 D Capsule are Silodosin and Dutasteride. It is a combination medicine and belongs to the category of selective alpha-1 adrenergic receptor antagonists.

What is the mode of the action of Sildoease-4 D Capsule?

The primary mechanism of Sildoease-4 D Capsule is by blocking alpha receptors present on the surface of the prostate, urinary bladder and urethra, thereby relaxing the smooth muscles of the bladder and prostate gland and enhancing the urine flow.

Last Updated On 05 Mar. 2025 | 3:43PM (IST)

Manufacturer details

Leo House, Shaheed Bhagat Singh Nagar, Dugri Dhandra Road, Near Joseph School Ludhiana PB 141002 IN

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

RAPAFLO ® (silodosin) Capsule for oral use. (n.d.). Fda.Gov.(Retrieved December 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022206s012lbl.pdf
Silodosin. (n.d.). Medlineplus.Gov. (Retrieved December 2023). https://medlineplus.gov/druginfo/meds/a609002.html
Dutasteride. (n.d.). Medlineplus.Gov. (Retrieved December 2023). https://medlineplus.gov/druginfo/meds/a603001.html
Westfall, T.C., MacArthur, H., Westfall, D.P. (2018). Adrenergic Agonists and Antagonists. In Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (13th ed., pp. 209, 221t, 523t). essay, McGraw Hill Medical.
Urorec. (n.d.). Europa.Eu.(Retrieved December 2023). https://www.ema.europa.eu/en/medicines/human/EPAR/urorec
DailyMed - RAPAFLO- silodosin capsule. (n.d.). Nih.Gov. (Retrieved December 2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=96425d91-cfe1-477d-a130-b58c330ca8a3
Dutasteride. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB0112

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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