Sepamet Xr 50/500 MG Tablet 10

Sepamet Xr 50/500 MG Tablet 10 interacts with the following medicines:

• Carbonic anhydrase inhibitors: Medications such as acetazolamide or methazolamide may interact with Sepamet Xr 50/500 MG Tablet 10, increasing the risk of lactic acidosis due to metformin.
• Insulin and insulin secretagogues: When taken with Sepamet Xr 50/500 MG Tablet 10, insulin and sulfonylureas like glimepiride or glibenclamide can cause low blood sugar (hypoglycaemia).
• Cationic medicines: Medicines like amiloride or quinidine, which are excreted via renal tubular secretion, may interact with Sepamet Xr 50/500 MG Tablet 10, leading to an accumulation of metformin.
• Diuretics: Furosemide may increase plasma levels of metformin when used with Sepamet Xr 50/500 MG Tablet 10, enhancing its blood glucose-lowering effect.
• Calcium channel blockers: Nifedipine may interact with Sepamet Xr 50/500 MG Tablet 10, leading to increased absorption and peak concentration (Cmax) of metformin.

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Sepamet Xr 50/500 MG Tablet 10 interacts with the following diseases:

• Renal impairment: Patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²) should avoid Sepamet Xr 50/500 MG Tablet 10 due to the risk of medicine accumulation and potential toxicity.
• Liver disease: Patients with liver disease should use Sepamet Xr 50/500 MG Tablet 10 cautiously, as it may impact the metabolism of the medication.
• Congestive heart failure: Those with heart failure requiring medication should exercise caution when taking Sepamet Xr 50/500 MG Tablet 10, as it may worsen their condition.
• Vitamin B12 deficiency: The metformin component in Sepamet Xr 50/500 MG Tablet 10 can reduce Vitamin B12 levels; therefore, individuals with a deficiency should be monitored closely.
• Hypoxic states: Conditions like cardiovascular collapse (shock) can increase the risk of lactic acidosis, necessitating careful monitoring when using Sepamet Xr 50/500 MG Tablet 10.

You should take Sepamet Xr 50/500 MG Tablet 10 as instructed by your doctor. The dosage can vary based on your individual health condition and response to the medication.

If you accidentally take more Sepamet Xr 50/500 MG Tablet 10 than prescribed, you may experience symptoms like nausea, weakness, or diarrhoea. If these symptoms occur, kindly consult your doctor.

If you miss a dose of Sepamet Xr 50/500 MG Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.