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CompositionPruease 1mg Tablet is used to manage chronic constipation in adults, especially when other laxatives have not been effective. It stimulates bowel movements and improves stool consistency.
Follow your doctor’s instructions on dosage. Before starting, inform your doctor about ongoing medications or pre-existing conditions. Report any side effects and continue taking the medicine for the prescribed duration.
Pruease 1mg Tablet is used to manage chronic idiopathic constipation, improve bowel movement frequency, and enhance stool consistency. It helps relieve infrequent or difficult bowel movements, providing relief when other laxatives have been ineffective, supporting overall digestive health.
To ensure optimal use of Pruease 1mg Tablet, adhere to the following guidelines:
Swallow the tablet as a whole with a glass of water.
Do not crush or chew the tablet.
Take the medicine with or without food, as per your preference.
Stick to the recommended dosage and duration as advised by your doctor.
Refrain from exceeding the prescribed dose without consulting your doctor.
Pruease 1mg Tablet is taken orally.
Pruease 1mg Tablet may cause headache, nausea, diarrhea, abdominal pain, decreased appetite, dizziness (lightheadedness, unsteadiness), and vomiting.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pruease 1mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Try taking Pruease 1mg Tablet with food.
Nausea: If you feel sick after taking this medicine, consider taking it after meals to lessen this effect.
Pruease 1mg Tablet contains prucalopride (1 mg). This ingredient works in your body as follows:
Stimulates Acetylcholine Release: Prucalopride stimulates the release of a neurotransmitter called acetylcholine in your body. Neurotransmitters are chemicals that transmit signals in your body.
Increases Intestinal Motility: By releasing more acetylcholine, prucalopride boosts the movement of muscles in your intestines. This process, known as intestinal motility, helps move food through your digestive system.
Improves Peristaltic Contractions: Prucalopride increases the frequency of peristaltic contractions – the coordinated squeezing and relaxing of muscles that move food along your digestive tract. This leads to improved bowel movements and relief from constipation.
If you're expecting a baby, it's advisable to exercise caution when taking Pruease 1mg Tablet. Always consult your doctor before starting this medicine during pregnancy.
If you are breastfeeding, be sure to discuss this with your doctor before taking this medication.
It's wise to consult your doctor before consuming alcohol while taking this medicine.
Pruease 1mg Tablet should be used cautiously if you have severe liver problems. Your doctor may need to adjust the dose based on your condition.
People with serious kidney issues should take Pruease 1mg Tablet with care. Consult your doctor for advice tailored to your specific health situation.
Pruease 1mg Tablet may cause dizziness or fatigue, particularly in the initial days of treatment. Be careful when driving or operating machinery until you know how the medicine affects you.
Don't take this medicine if you're allergic to prucalopride or any other components of Pruease 1mg Tablet. If you notice symptoms like rash, itching, or difficulty breathing, seek immediate medical attention.
Pruease 1mg Tablet is intended for adults only. Always consult your doctor before giving any medicine to a child.
If you’re over 70 years old, proceed with caution when using Pruease 1mg Tablet. Older patients may be more susceptible to its side effects and may have other health considerations such as liver or kidney issues. Your doctor will provide guidance based on your health status.
Strong CYP3A4 inhibitors: Medicines like ketoconazole and clarithromycin can interact with Pruease 1mg Tablet, potentially altering the action of the medication.
QT interval-prolonging medications: Medicines such as pimozide and cisapride may cause interactions when taken with Pruease 1mg Tablet, leading to changes in heart rhythm.
Anticholinergic agents: Medicines like atropine and scopolamine may interact with Pruease 1mg Tablet, possibly affecting its ability to increase intestinal motility.
There's no known interaction between Pruease 1mg Tablet and any specific foods.
Severe kidney impairment: If you have severe kidney problems, you should use Pruease 1mg Tablet cautiously as the medicine's effects might be altered.
Severe liver impairment: Pruease 1mg Tablet should be used with caution if you have serious liver issues since your body's response to the medicine could change.
Psychiatric disorders: If you've had depression or suicidal thoughts in the past, your doctor should monitor you closely while you're taking Pruease 1mg Tablet.
The daily dose of Pruease 1mg Tablet should be taken as your doctor prescribes. The dosage may vary depending on factors such as your condition's severity and how you respond to the medicine. Always follow the prescribed dosage, and never exceed it without consulting your doctor.
Overdosing on Pruease 1mg Tablet may cause common side effects to become more severe. If you suspect an overdose, inform your doctor. It's important not to panic but act responsibly, following your doctor's advice.
If you forget to take Pruease 1mg Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't double up the dose to make up for a missed one.
Store Pruease 1mg Tablet at room temperature.
The medicine should be kept in its original packaging to shield it from light and moisture.
Ensure the tablet is always placed out of reach of children.
Always check the expiry date before using the medicine.
Drinking adequate water can help soften stools and ease constipation, making Pruease 1mg Tablet more effective.
Consumsing plenty of fruits, vegetables, and whole grains can help improve bowel movements. This dietary change can support the effectiveness of Pruease 1mg Tablet in managing chronic constipation.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Chronic Idiopathic Constipation |
| Drug Category | 5-HT4 Receptor Agonist |
| Therapeutic Category | Laxative |
Pruease 1mg Tablet is used to manage chronic idiopathic constipation in adults, especially when other laxatives have not provided adequate relief.
Pruease 1mg Tablet contains prucalopride, which stimulates bowel movements by increasing the activity of the intestines, leading to improved stool passage.
Yes, you can take Pruease 1mg Tablet with or without food as it doesn't affect the medicine's effectiveness.
Common side effects include headache, nausea, diarrhoea, abdominal pain, decreased appetite, dizziness and vomiting. If these persist or worsen, consult your doctor.
If you're pregnant or planning to become pregnant, consult your doctor before using this medicine.
Pruease may cause dizziness or fatigue. Until you know how the medication affects you, exercise caution when driving or operating machinery.
Store Pruease 1mg Tablet at room temperature, protected from light and moisture. Keep it out of reach of children and pets.
Check out Editorial Policy
Shire. (2018). Highlights of prescribing information for motegrity [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210166s000lbl.pdf
Prucalopride: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a619011.html
DailyMed - MOTEGRITY- prucalopride tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bca1e4c6-4b2b-4876-8ab3-654629c4ff1b
Prucalopride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06480
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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