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CompositionImeglyn 1000 Tablet is used to manage type 2 diabetes by improving insulin sensitivity and reducing insulin resistance. It regulates glucose production in the liver and enhances sugar uptake in the muscles to support effective blood sugar control.
This medication is typically prescribed when diet and exercise alone are insufficient. Take this treatment exactly as directed by your doctor to maintain healthy glucose levels.
Imeglyn 1000 Tablet is used to manage type 2 diabetes mellitus by helping control blood sugar levels. It improves the body’s sensitivity to insulin and reduces glucose production in the liver, supporting more stable sugar levels throughout the day. Regular use of this medicine aids long-term diabetes management and may help prevent complications such as nerve damage, kidney issues, and other problems associated with uncontrolled blood sugar.
Before starting Imeglyn 1000 Tablet, follow these instructions:
It is taken orally with a glass of water.
Swallow the tablet whole. Avoid crushing or chewing.
Do not exceed the recommended dose without consulting your doctor.
Remember, never stop taking this medicine without first discussing it with your doctor.
Imeglyn 1000 Tablet is taken orally.
Imeglyn 1000 Tablet may cause some common side effects, including hypoglycemia, which is a drop in blood sugar leading to symptoms such as dizziness, sweating, and trembling. Other possible effects include nausea, vomiting, diarrhea, headache, and dizziness.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Imeglyn 1000 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some tips to manage common side effects:
Hypoglycemia: If you experience symptoms of low blood sugar, such as trembling or dizziness, try consuming a quick source of sugar, such as fruit juice or sweets.
Nausea/Vomiting: To minimise these effects, try taking Imeglyn 1000 Tablet with meals.
Imeglyn 1000 Tablet contains Imeglimin (1000 mg), which works in the body as follows:
Promotes Insulin Secretion: Imeglimin stimulates the secretion of insulin from pancreatic beta cells in a glucose-dependent manner. This helps control blood glucose levels.
Enhances Insulin Sensitivity: It works to improve insulin sensitivity and reduce insulin resistance in target tissues, helping your body use insulin more effectively.
Inhibiting Glucose Production: Imeglimin inhibits hepatic glucose production by downregulating key gluconeogenic enzymes, contributing to better blood glucose control.
Protects Vascular Cells: The medicine also reduces hyperglycaemia-induced cell death in vascular endothelial cells, protecting blood vessels.
Increases Glucose Uptake: Imeglimin may help increase glucose uptake into muscle tissues, contributing to the overall management of blood glucose levels.
Caution is advised while taking Imeglyn 1000 Tablet if you are pregnant. It is best to consult your doctor before starting this medication.
It's better to avoid this medication if you are breastfeeding.
There are no specific warnings about consuming alcohol while on Imeglyn 1000 Tablet. However, it's always wise to discuss this with your doctor.
If you have liver problems, caution is advised when starting Imeglyn 1000 Tablet, especially in severe cases. Discuss your liver health with your doctor before starting the medication.
Caution is recommended if you have a history of kidney problems. Consult your doctor before you start taking Imeglyn 1000 Tablet.
Imeglyn 1000 Tablet may cause dizziness as a side effect. If you experience this, avoid driving or operating heavy machinery until these symptoms subside.
If you have a known allergy to Imeglimin or any other ingredients in this medicine, avoid taking Imeglyn 1000 Tablet.
The safety and efficacy of Imeglyn 1000 Tablet haven't been established in children and adolescents under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take this medicine under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Imeglyn 1000 Tablet interacts with the following medicines:
Insulin and insulin secretagogues: If you take insulin or medicines that stimulate insulin production (like glimepiride or glipizide), Imeglyn 1000 Tablet could increase your risk of hypoglycemia (low blood sugar levels).
OCT2 transporter substrates, inhibitors, or inducers: Medicines like metformin or cimetidine that affect these transporters might interact with Imeglyn 1000 Tablet, potentially altering its absorption, distribution, metabolism, or excretion.
Medicines undergoing active renal tubular secretion: Since Imeglyn 1000 Tablet is primarily eliminated via the kidneys, it may interact with medicines like penicillin or methotrexate that also undergo active renal secretion.
There are no specific known food interactions with Imeglyn 1000 Tablet.
Imeglyn 1000 Tablet interacts with the following diseases:
Renal impairment: If you have moderate kidney disease, your doctor may need to adjust your dose of Imeglyn 1000 Tablet. It's not recommended if you have severe kidney disease.
Hepatic impairment: If your liver isn't working well, especially in severe cases, you should use Imeglyn 1000 Tablet cautiously.
Pancreatitis and gallstones: If you've had pancreatitis (inflammation of the pancreas) or gallstones before, you should take care when using this medicine.
The daily dose of Imeglyn 1000 Tablet should be taken as recommended by your doctor. The dosage may vary based on individual factors, such as the severity of your condition and how well you respond to the treatment. Always adhere to the prescribed dosage, and don’t increase it without consulting your doctor.
If you happen to take more than the recommended dose of Imeglyn 1000 Tablet, you might experience symptoms like severe low blood sugar levels. In case of any persisting or worsening symptoms, inform your doctor.
If you forget to take your regular dose of Imeglyn 1000 Tablet, take it as soon as you can remember. However, if it's almost time for your next dose, leave out the missed one and continue with your usual schedule. You must avoid increasing your dose without discussing it with your doctor.
Store Imeglyn 1000 Tablet at a temperature below 30°C.
Keep this medicine protected from light and moisture.
Do not store in places of high humidity or near heat sources.
Ensure the medicine is kept out of reach and sight of children.
Always check the expiry date before using Imeglyn 1000 Tablet.
Follow a balanced diet low in sugars and high in fibre to help manage your blood glucose levels effectively. This will support the action of Imeglyn 1000 Tablet.
Regular physical activity, ideally 30 minutes a day, can help improve insulin sensitivity and assist in managing type 2 diabetes. Always consult your doctor before starting any new exercise regimen.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | Blood Glucose-Lowering Agent |
| Therapeutic Category | Antidiabetic |
Imeglyn 1000 Tablet is an oral medicine that helps manage type 2 diabetes in adults. It should be used with a balanced diet and regular exercise.
If you have moderate kidney disease, your doctor might adjust your dose. However, it's not recommended if you have severe kidney disease.
Use Imeglyn 1000 Tablet during pregnancy or breastfeeding only if your doctor thinks the benefits outweigh the risks.
No, the safety and effectiveness of Imeglyn 1000 Tablet aren't established in people under 18 years old.
Take the missed dose as soon as you remember, unless it's nearly time for your next dose. Don't take two doses at once.
It has a novel mechanism that targets mitochondrial function in cells, and unlike some other antidiabetic agents, it doesn't cause weight gain.
Yes, trials up to 24 weeks have shown it to be generally safe and well-tolerated. Long-term safety data is being generated.
Check out Editorial Policy
R.M.P. (n.d.). Imeglimin hydrochloride 500mg Film Coated tablet. https://www.centaurpharma.com/downloads/2024/diabetology/Imeclass.pdf
Hallakou‐Bozec, S., Vial, G., Kergoat, M., Pascale Fouqueray, Bolze, S., Borel, A., Fontaine, E., & Moller, D. E. (2020). Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes. Diabetes Obesity and Metabolism, 23(3), 664–673. https://doi.org/10.1111/dom.14277
Huston, J., Schaffner, H., Langley, L., Skrable, B., Ashchi, A., Berner, J., Gore, A., Sheikh-Ali, M., Sutton, D., & Rebecca Goldfaden. (2022). Imeglimin in type 2 diabetes. In Drugs of Today (Vol. 9, pp. 437–449) [Journal-article]. https://doi.org/10.1358/dot.2022.58.9.3419555
Doupis, J., Baris, N., Avramidis, K., & TOUCH MEDICAL MEDIA. (2021). Imeglimin: a new promising and effective weapon in the treatment of type 2 diabetes. In touchREVIEWS in Endocrinology (pp. 88–91). https://www.touchendocrinology.com/wp-content/uploads/sites/5/2021/11/touchENDO_17-2_pp88-91-1.pdf
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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