Glimetop Mp 1/500/15 MG Tablet 10

Rpg Life Sciences Ltd.

Pack of 10 Units

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Composition

Glimepiride (1 Mg) + Metformin (500 Mg) + Pioglitazone (15 Mg)

Glimetop Mp 1/500/15 MG Tablet 10 is used to manage Type 2 Diabetes mellitus in adults. It is a combination medicine that belongs to a class of medications known as oral anti-diabetic agents.

This medicine helps control blood sugar levels when diet, exercise, and single-agent treatments are insufficient. It helps prevent long-term complications of diabetes, such as kidney damage, nerve problems, vision loss, and cardiovascular issues that can develop when blood sugar remains uncontrolled.

This medicine should be taken orally as directed by your doctor. The dosage depends on the severity of your condition and your body's response to the treatment. Before starting this medicine, inform your doctor about any pre-existing conditions, especially kidney or liver disease, and any allergies to salicylates like aspirin. If you experience any side effects while taking this medicine, notify your doctor promptly. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

Glimetop Mp 1/500/15 MG Tablet 10 is used for the following:

Treatment of Type 2 Diabetes mellitus in adults
Control of blood sugar levels
Management of diabetes when single medicines fail
Prevention of diabetes complications
Protection against kidney damage from diabetes
Reduction of nerve problems in diabetic patients
Prevention of diabetes-related vision loss
Lowering the risk of cardiovascular issues in diabetics

Follow these instructions while taking Glimetop Mp 1/500/15 MG Tablet 10:

Take the tablet orally once daily with meals.
Swallow the tablet whole with a glass of water.
Do not crush, break, or chew the tablet.
Take this medicine at the same time each day.
Monitor your blood sugar levels regularly whilst taking this medicine.
Continue taking this medicine for as long as your doctor advises.

Glimetop Mp 1/500/15 MG Tablet 10 is taken orally.

Glimetop Mp 1/500/15 MG Tablet 10 may have the following common side effects:

Hypoglycaemia: This refers to low blood sugar levels, which may cause sweating, shakiness, confusion, and hunger.
Nausea
Vomiting
Diarrhoea
Headache
Weight gain: You might notice a gradual increase in your body weight while taking this medicine.
Dizziness

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glimetop Mp 1/500/15 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Taking Glimetop Mp 1/500/15 MG Tablet 10 with meals can help reduce feelings of sickness.
Hypoglycaemia: Having a small snack when taking this medicine may help prevent low blood sugar episodes.

Glimetop Mp 1/500/15 MG Tablet 10 contains three active ingredients that work together to manage diabetes:

Glimepiride (1 mg): Stimulates the pancreas to secrete more insulin, which helps your body cells absorb glucose from the bloodstream, thereby reducing blood sugar levels.
Metformin (500 mg): Decreases glucose production in the liver and improves insulin sensitivity in body tissues, allowing cells to use insulin more effectively and lower blood sugar levels.
Pioglitazone (15 mg): Increases the sensitivity of muscle, fat, and liver cells to insulin, enabling them to absorb glucose more efficiently, which helps maintain proper blood sugar control.

Pregnancy

Caution is advised while taking Glimetop Mp 1/500/15 MG Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Glimetop Mp 1/500/15 MG Tablet 10 during breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Avoid consuming alcohol while taking Glimetop Mp 1/500/15 MG Tablet 10. Alcohol may increase the risk of hypoglycaemia (low blood sugar) and lactic acidosis (a rare but serious condition where lactic acid builds up in your body).

Liver

Caution is advised while taking Glimetop Mp 1/500/15 MG Tablet 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before using Glimetop Mp 1/500/15 MG Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

Take care while driving or operating machinery as this medicine may cause dizziness or hypoglycaemia. If you experience these symptoms, avoid such activities until you feel better.

Allergy

If you have a known allergy to glimepiride, metformin, pioglitazone, or other medicines, inform your doctor before taking Glimetop Mp 1/500/15 MG Tablet 10. Allergic reactions require immediate medical attention.

Children

Caution is advised while giving Glimetop Mp 1/500/15 MG Tablet 10 to children under 18. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Glimetop Mp 1/500/15 MG Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Your doctor may need to adjust the dosage based on your kidney function and overall health status.

Drug-Drug Interactions

Glimetop Mp 1/500/15 MG Tablet 10 interacts with the following medicines:

Antidiabetic agents: Medicines like glibenclamide, gliclazide and insulin may increase the risk of hypoglycaemia (low blood sugar) when taken with this tablet.
Thiazide diuretics: Medicines such as hydrochlorothiazide or chlorthalidone can decrease the effectiveness of this tablet in controlling blood sugar.
Corticosteroids: Medicines like prednisolone or dexamethasone can increase blood glucose levels, potentially reducing the effectiveness of the tablet.
Sympathomimetic agents: Medicines such as salbutamol or terbutaline may increase blood sugar levels, counteracting the effects of the tablet.

Drug-Food Interactions

Glimetop Mp 1/500/15 MG Tablet 10 should be taken with meals to reduce stomach upset. No specific food interactions are known, but maintaining consistent carbohydrate intake helps maintain stable blood sugar levels.

Drug-Disease Interactions

Glimetop Mp 1/500/15 MG Tablet 10 interacts with the following diseases:

Type 1 diabetes: This medicine is not suitable for type 1 diabetes as it requires functioning pancreatic cells to work properly.
Severe kidney problems: Patients with kidney impairment may experience increased risk of lactic acidosis (dangerous acid buildup in the blood) from the metformin component.
Liver disease: Reduced liver function can affect how the medicine is processed, potentially increasing side effects and toxicity.
Heart failure: Pioglitazone component may worsen fluid retention and heart failure symptoms in susceptible patients.

Daily Dose

The daily dose of Glimetop Mp 1/500/15 MG Tablet 10 should be taken as prescribed by your doctor. Your dosage may change based on your blood sugar levels and how you respond to treatment. Always follow your doctor's instructions carefully.

Over Dose

Taking too much of this medicine may cause low blood sugar (hypoglycaemia), nausea, stomach upset, headache, or dizziness. If you experience these symptoms after taking extra tablets, consult your doctor promptly for guidance.

Missed Dose

If you forget to take your tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Never take a double dose to make up.

Glimetop Mp 1/500/15 MG Tablet 10 should be stored in these ways:

Store this tablet at room temperature.
Keep in a dry place away from direct sunlight and moisture.
Store it in the original packaging to protect it from environmental exposure.
Keep out of reach of children.
Do not use this medicine after the expiry date printed on the package.

Monitor your carbohydrate intake and choose complex carbohydrates (like whole grains) over simple sugars to help manage your blood glucose (sugar) levels throughout the day.
Engage in regular physical activity, such as 30 minutes of brisk walking five days a week, to improve insulin sensitivity (how effectively your body uses insulin).

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 diabetes, Insulin resistance
Drug Category	Triple anti-diabetic combination
Therapeutic Category	Anti-diabetic medication

Can Glimetop Mp 1/500/15 MG Tablet 10 be used as a first-line treatment for type 2 diabetes?

No, it's typically prescribed when diet, exercise, or single medicines alone don't adequately control blood sugar levels.

How does Glimetop Mp 1/500/15 MG Tablet 10 work in the body?

It works through three mechanisms: stimulating insulin release, reducing glucose production in the liver, and improving the body's response to insulin.

Should I take this medicine with or without food?

Take it with meals to reduce stomach discomfort. Food helps your body absorb the medicine properly and lowers the risk of digestive side effects.

What are the common side effects of Glimetop Mp 1/500/15 MG Tablet 10?

Common side effects include low blood sugar (hypoglycaemia), stomach upset, headache, dizziness, and sometimes weight gain.

Can I drink alcohol while taking this medicine?

No, avoid alcohol completely. It increases your risk of low blood sugar and lactic acidosis, a rare but serious condition affecting blood acid levels.

What should I do if I miss a dose?

Take it as soon as you remember. If it's nearly time for your next dose, skip the missed one. Never take a double dose to make up.

How should I store Glimetop Mp 1/500/15 MG Tablet 10?

Store it at room temperature, in a dry place away from direct sunlight and moisture. Keep it out of children's reach.

Last Updated On 05 Jun. 2025 | 11:05AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 9 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

RPG House, 463, Dr. Annie Besant Road, Worli, Mumbai 400030

Country of origin: INDIA

Expiry on or after: August 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). Drug Information. Retrieved April 1, 2025, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=07ad4366-4b21-f633-49f3-c2b35f88168d
Metformin: MedlinePlus drug information. (2024, February 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a696005.html
NHS. (n.d.). Pioglitazone. Retrieved April 1, 2025, from https://www.nhs.uk/medicines/pioglitazone/about-pioglitazone/
KOMBIGLYZE® XR (kom-be-glyze X-R) (saxagliptin and metformin HCl extended-release) tablets. (n.d.). U.S. Food and Drug Administration. https://www.fda.gov/downloads/drugs/drugsafety/ucm280360.pdf
Takeda Pharmaceuticals America, Inc. (2009, September). ACTOPLUS MET® (ak-TŌ-plus-met) (pioglitazone hydrochloride and metformin hydrochloride) tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021842s009MedGuide.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Telephone:09240250346

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