Fenceta 325 Tablet 15

Alkem Laboratories Ltd.

Strip of 15 Units

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Old MRP ₹32.5

MRP ~~₹30.45~~

₹25.57

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Composition

Ibuprofen (400 Mg) + Paracetamol/acetaminophen (325 Mg)

Fenceta 325 Tablet is used in the treatment of acute painful and inflammatory conditions across a broad range of disorders, and is also effective in reducing fever. This is a combination medicine, typically containing Ibuprofen (an NSAID) and Paracetamol/Acetaminophen (an analgesic and antipyretic), which work together to provide comprehensive relief: Ibuprofen reduces swelling and pain by inhibiting prostaglandin production, while Paracetamol enhances the pain-relieving effect and actively lowers body temperature. This dual action makes it a suitable choice for managing symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, headaches, dental pain, and menstrual cramps.

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Fenceta 325 Tablet is used to manage osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, headache, dental pain, menstrual cramps, muscle pain, and fever. It effectively reduces pain and inflammation in these conditions, providing relief from discomfort and improving overall mobility and well-being.

Here's how you should take Fenceta 325 Tablet:

Swallow the tablet whole with a glass of water. Do not chew or crush it.
Try taking this medicine with food or milk if it upsets your stomach.
Do not exceed the recommended dose unless advised by your doctor.
If your symptoms persist or worsen, consult your doctor immediately.

Fenceta 325 Tablet is taken orally.

Fenceta 325 Tablet may cause nausea, abdominal pain, diarrhea, constipation, dizziness, headache, nervousness, rash, itchiness, and tinnitus.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the Fenceta 325 Tablet. However, if you experience severe side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dyspepsia: If you have indigestion after taking this medicine, try taking it with food or milk to lessen this effect.
Diarrhoea: Consider taking this medicine with food to reduce the risk of diarrhoea.

Keep your doctor informed if you face any severe side effects.

Fenceta 325 Tablet is a combination of two active ingredients:

Ibuprofen (400 mg): This component acts as a non-selective inhibitor of an enzyme known as cyclooxygenase (COX). COX is vital in producing prostaglandins - substances in your body that mediate pain, inflammation and fever. By inhibiting COX, ibuprofen effectively reduces these symptoms.
Paracetamol/Acetaminophen (325 mg): This ingredient works primarily in the brain to inhibit COX. Its action leads to its analgesic (pain-relieving) and antipyretic (fever-reducing) effects.

Combining these two agents in Fenceta 325 Tablet provides multi-faceted relief from pain and reduces fever through both peripheral (body-wide) and central (in the brain) mechanisms of action.

Pregnancy

Fenceta 325 Tablet is not recommended during the third trimester of pregnancy due to potential risks to the unborn child. If you are pregnant or planning to conceive, consult your doctor before taking this medicine.

Breastfeeding

Both ibuprofen and paracetamol are excreted in human milk. If you are breastfeeding, it's crucial to consult your doctor before using Fenceta 325 Tablet.

Alcohol

Alcohol consumption during treatment with Fenceta 325 Tablet may increase the risk of liver damage. It is advisable to limit alcohol intake while taking this medicine.

Liver

This medication is not suggested for patients with severe liver impairment. If you have any liver-related health problems, discuss them with your doctor before starting Fenceta 325 Tablet.

Kidney

Caution is advised before using Fenceta 325 Tablet if you have kidney health issues. Discuss these concerns with your doctor before starting this medication.

Using Machines & Driving

Fenceta 325 Tablet may cause dizziness or nervousness in some patients, which could affect your ability to drive or operate machinery. Be cautious if experiencing these symptoms.

Allergy

Avoid using Fenceta 325 Tablet if you have known allergies to ibuprofen, paracetamol or any other ingredients in its formulation.

Children

Caution is advised while giving these tablets to children . Always consult your doctor before giving this medicine to a child.

Older Patients

Elderly patients should take Fenceta 325 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Fenceta 325 Tablet interacts with the following medicines:

Anticoagulants: Medicines like warfarin may interact with Fenceta 325 Tablets, increasing the risk of bleeding.
Aspirin: Taking aspirin with this medicine may increase the risk of gastrointestinal discomfort.
Diuretics: Due to its NSAID component, medicines such as furosemide may have a reduced effect when taken with Fenceta 325 Tablets.
Lithium: NSAIDs in Fenceta 325 Tablet can increase serum lithium levels, potentially leading to toxicity.
Methotrexate: Concurrent use may increase serum methotrexate levels, which could cause toxic effects.

Drug-Food Interactions

Fenceta 325 Tablet doesn't have any known specific interactions with food. However, taking it with food or milk is generally advised to reduce the risk of stomach upset. Please consult your doctor and share your concerns with them.

Drug-Disease Interactions

Fenceta 325 Tablet interacts with the following diseases:

Liver disease: In individuals with severe liver impairment, this medicine could worsen their condition due to the presence of paracetamol.
Kidney disease: Long-term use of Fenceta 325 Tablet might result in renal injury due to its NSAID content.
Heart failure: Patients with severe heart failure should exercise caution when taking this medicine as it contains an NSAID, which could exacerbate their condition.

Daily Dose

The daily dose of Fenceta 325 Tablet should be taken as directed by your doctor. The dosage may vary based on factors such as the severity of your condition and how you respond to the medicine. Sticking to the prescribed dosage and not exceeding it without consulting your doctor is vital.

Over Dose

An accidental overdose of Fenceta 325 Tablets can lead to symptoms such as feeling sick, stomach pain, and dizziness. If you experience these symptoms after taking more than the recommended dose, you should inform your doctor promptly.

Missed Dose

If you've missed a dose of Fenceta 325 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without talking to your doctor.

Storage instructions for these tablets are as fllows:

The ideal storage temperature is below 30°C.
Avoid exposure to excessive heat and direct sunlight.
Be sure to keep this medicine out of reach of children.
Always use the tablet before its expiry date.

Here are dietary and lifestyle guidance for Fenceta 325 Tablet:

If you're dealing with arthritis or muscle pain, try to include foods rich in omega-3 fatty acids, such as fish, walnuts, and flaxseeds. These can help reduce inflammation.
Regular gentle exercises such as swimming or walking can help manage arthritis pain and improve joint flexibility. However, do consult your doctor before starting any exercise routine.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Osteoarthritis, Rheumatoid Arthritis, Headache
Drug Category	COX Inhibitor
Therapeutic Category	Non-steroidal Anti-inflammatory

What is Fenceta 325 Tablet used for?

Fenceta 325 Tablet manages acute painful and inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and headache.

How does Fenceta 325 Tablet work?

This medicine combines ibuprofen and paracetamol, which work together to relieve pain and reduce fever through multiple mechanisms of action.

Is Fenceta 325 Tablet safe to take during pregnancy?

There could be risks when taking NSAIDs like ibuprofen during the third trimester of pregnancy. Always consult your doctor before using any medicine during pregnancy.

Can I take this medicine for a headache?

Yes, due to its analgesic properties, Fenceta 325 Tablet can be used to manage headaches.

How long can I safely use Fenceta 325 Tablet?

You should use the lowest effective dose for the shortest duration possible. Follow your doctor's instructions regarding the duration and consult them if symptoms persist or worsen.

Are there any specific contraindications for this medicine?

Yes, this medicine should not be taken if you have severe liver or kidney impairment, active peptic ulcer or gastrointestinal bleeding, and severe heart failure.

What are the common side effects of Fenceta 325 Tablet?

Common side effects include nausea, abdominal pain, dizziness, rash, and edema. If you experience any unusual symptoms, promptly consult your doctor.

Last Updated On 03 Dec. 2025 | 12:24PM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

Expiry on or after: April 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). Ibuprofen - Ibuprofen tablet. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm
MedlinePlus. (n.d.). Ibuprofen. https://medlineplus.gov/druginfo/meds/a681004.html
U.S. Food and Drug Administration. (2005). https://www.accessdata.fda.gov/drugsatfda_docs/nda/2005/021393s000_Advil_PM_MedR.pdf
U.S. Food and Drug Administration. (2006). Label: Paracetamol- paracetamol tablet. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/040330s015,040341s013,040434s003lbl.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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