Etofree 400 Tablet 10

Lupin Ltd

Strip of 10 Units

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MRP ~~₹131.1~~

₹104.88

₹13.11/Units

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Composition

Etodolac (400 Mg)

Strength:

300 MG 400 MG 200 MG

Etofree 400 Tablet 10 is primarily used to manage the pain, inflammation, and joint stiffness associated with conditions like rheumatoid arthritis and osteoarthritis. This medicine belongs to a group of medications known as NSAIDs.

This tablet is used to get relief from the signs and symptoms of juvenile rheumatoid arthritis. It is a type of arthritis that affects children and adolescents under the age of 16. It is a chronic inflammatory condition characterised by joint pain, swelling, and stiffness that can last for an extended period.

Before starting this tablet, it's crucial to consult your doctor, who will advise you on the correct dosage and frequency. You should inform your doctor about any preexisting diseases or ongoing medication. If you notice any side effects while on this medicine, promptly notify your doctor. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Etofree 400 Tablet 10 is used for:

Managing signs and symptoms of rheumatoid arthritis
Reducing discomfort in osteoarthritis
Alleviating pain, inflammation, and stiffness in juvenile rheumatoid arthritis

Swallow the tablet whole with a full glass of water.
Do not crush or chew the tablet.
This medicine can be taken with or without meals.
Avoid taking more than the recommended dose without consulting your doctor.
It's important not to stop taking this medicine without speaking to your doctor first.

Etofree 400 Tablet 10 is taken orally.

Etofree 400 Tablet 10 may have the following common side effects:

Abdominal pain
Constipation
Diarrhoea
Indigestion
Flatulence
Nausea and vomiting

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Etofree 400 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some tips to manage common side effects:

Indigestion: If you are experiencing indigestion, try taking the medicine after meals to lessen this effect.
Nausea and vomiting: Taking the medicine with food could help manage these symptoms.

Etofree 400 Tablet 10 contains Etodolac (400 mg), which works on the body through the following mechanisms:

Inhibition of Prostaglandin Production: Etodolac works by blocking the cyclooxygenase (COX) enzyme, which is essential in forming prostaglandins in the body. Prostaglandins are chemicals that contribute to inflammation, pain, and fever.
Reduction of Pain and Inflammation: By inhibiting the COX enzyme, Etodolac effectively reduces prostaglandin production, leading to decreased pain and inflammation.

Pregnancy

Etofree 400 Tablet 10 is generally not recommended during the later stages of pregnancy, particularly after the 30th week, due to potential adverse effects on foetal health. Pregnant women should always consult their doctor before using this medication to thoroughly assess the potential risks and determine if the benefits outweigh them.

Breastfeeding

Etodolac, the active ingredient in Etofree 400 Tablet 10, can pass into breast milk, posing potential risks to the nursing infant. Breastfeeding mothers should discuss the benefits and risks with their doctor, who may advise either discontinuing breastfeeding or finding an alternative treatment to Etodolac.

Alcohol

Caution is advised when consuming alcohol while on Etofree 400 Tablet 10, as it may increase the risk of gastrointestinal side effects. Consulting your doctor can help you understand how best to manage alcohol intake.

Liver

Individuals with liver conditions should exercise caution when using Etofree 400 Tablet 10, as it may affect liver function. A complete assessment by a doctor is recommended to determine the appropriate dosage and to monitor liver function periodically to minimise risks.

Kidney

Patients with preexisting kidney issues should use Etofree 400 Tablet 10 with caution. The medication can impair kidney function further, especially in those with moderate to severe renal conditions. It is essential to consult a doctor, who may adjust the dosage or recommend alternative options.

Using Machines & Driving

Dizziness may occur as a side effect, especially after starting the medication. Avoid driving or operating heavy machinery until you know how this medicine affects you.

Allergy

Do not take Etofree 400 Tablet 10 if you are allergic to Etodolac or any of its components. Additionally, those who have had allergic reactions to aspirin or other NSAIDs should avoid this medicine to reduce the risk of serious allergic reactions.

Children

Etofree 400 Tablet 10 should be administered with caution in children and only under a doctor’s guidance. Consult your doctor before giving this medication to anyone under 18 years of age.

Older Patients

Older adults, especially those over 70, may experience increased sensitivity to the side effects of Etofree 400 Tablet 10. Medical supervision is necessary, and your doctor may adjust the dosage based on your health condition.

Drug-Drug Interactions

Etofree 400 Tablet 10 interacts with the following medicines:

Anticoagulants: Medications like warfarin and heparin can increase the risk of bleeding when taken with Etofree 400 Tablet 10.
Antihypertensives: Medications used to lower blood pressure, such as enalapril or losartan, may be less effective if taken with this medication.
Diuretics: Medications like furosemide or hydrochlorothiazide may increase the risk of kidney problems when used alongside Etofree 400 Tablet 10.

Drug-Food Interactions

Eating a high-fat meal before taking this medication may delay its absorption, potentially delaying the onset of pain relief.

Drug-Disease Interactions

Etofree 400 Tablet 10 interacts with the following diseases:

Peptic Ulcer Disease: Individuals with peptic ulcers are at higher risk of gastrointestinal bleeding or ulceration if they take Etofree 400 Tablet 10.
Cardiovascular Disease: People with a history of heart disease should be cautious, as this medication may increase the risk of serious cardiovascular events, such as heart attack and stroke.

Daily Dose

Take the daily recommended dose of Etofree 400 Tablet 10 as prescribed by your doctor. Your doctor will decide the right dosage for you based on factors like your condition's severity and how you respond to the medicine. Always follow the prescribed dosage and don't exceed it without consulting your doctor.

Over Dose

In case of an overdose of Etofree 400 Tablet 10, you may experience symptoms such as nausea, vomiting, abdominal pain, drowsiness, dizziness, and headache. Don't panic if this happens but do inform your doctor about it.

Missed Dose

If you forget to take a dose of Etofree 400 Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed dose and continue with your regular dose schedule. Never increase your dosage without consulting your doctor.

Store Etofree 400 Tablet 10 at room temperature below 30°C.
Keep the tablet in its original container to protect it from light and moisture.
Make sure the medicine is out of reach of children.
Always check the expiry date and avoid using the tablet if it's past due.

Incorporating regular gentle exercise into your routine can help manage joint stiffness and improve mobility, which is beneficial for conditions like rheumatoid arthritis and osteoarthritis.
Aim to maintain a balanced diet rich in omega-3 fatty acids (found in fish, walnuts, and flaxseeds), as they have anti-inflammatory properties that can help manage inflammation associated with these conditions.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Rheumatoid Arthritis, Osteoarthritis, Juvenile Rheumatoid Arthritis
Drug Category	Prostaglandin Synthesis Inhibitor
Therapeutic Category	NSAID

What is Etofree 400 Tablet 10 used for?

Etofree 400 Tablet 10 is an oral medication that contains Etodolac, primarily used to manage pain, inflammation, and joint stiffness in conditions like rheumatoid arthritis and osteoarthritis.

How does Etofree 400 Tablet 10 work?

Etofree 400 Tablet 10 works by inhibiting the cyclooxygenase (COX) enzyme, which helps reduce the production of prostaglandins. This decrease in prostaglandins helps alleviate pain, inflammation, and fever.

Can I take Etofree 400 Tablet 10 on an empty stomach?

Yes, Etofree 400 Tablet 10 can be taken with or without food. For best results, swallow the tablet whole with a full glass of water.

What are the common side effects of Etofree 400 Tablet 10?

Common side effects may include abdominal discomfort, constipation, diarrhoea, dizziness, and headache. If these symptoms persist or worsen, it is advisable to contact your doctor.

Can I take other medications with Etofree 400 Tablet 10?

Some medications may interact with Etodolac and lead to complications. It’s crucial to inform your doctor about all medications you are taking to prevent adverse interactions.

Is Etofree 400 Tablet 10 safe during pregnancy?

Etodolac is generally not recommended during the later stages of pregnancy due to potential risks to foetal health. Always consult your doctor if you are pregnant or planning to become pregnant before taking this medication.

How should I store Etofree 400 Tablet 10?

Store Etofree 400 Tablet 10 at room temperature in a tightly closed container, away from light and moisture, and out of reach of children.

Last Updated On 04 Jun. 2025 | 12:42PM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 9 years

PhD in Chemistry

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

Expiry on or after: November 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Lodine XL (etodolac extended-release tablets). (N.d.). Fda.Gov. Retrieved November 2, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/020584s004,006,007lbl.pdf
Etodolac: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a692015.html
Etodolac: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00749
DailyMed - ETODOLAC tablet, extended-release. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=107ea9d7-80a9-41a4-b61e-168370127319

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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