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CompositionCrixan 500 Tablet is used to treat mild to moderate bacterial infections of the respiratory tract, skin, and soft tissues. It is also used to eradicate H. pylori bacteria in stomach ulcers and to prevent specific infections in patients with compromised immune systems.
Crixan 500 Tablet is used for a variety of bacterial infections, including sinusitis, bronchitis, and pneumonia. It is also effective for middle ear infections and dental issues. Additionally, it is used to eradicate H. pylori in peptic ulcer patients and prevent complex infections in individuals with HIV.
Here are some instructions to follow while taking Crixan 500 Tablet:
Swallow the tablet whole with a full glass of water.
The medicine can be taken with or without food.
Make sure to take the medicine at evenly spaced times for best results.
Do not crush, break, or chew the tablet.
Complete the full course prescribed by your doctor, even if your symptoms improve earlier. This helps to prevent a relapse of the infection.
Crixan 500 Tablet is taken orally.
Crixan 500 Tablet may cause diarrhea, nausea, vomiting, stomach pain, indigestion, headache, dizziness, anxiety, insomnia, and strange taste in the mouth.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Crixan 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are a couple of pointers to manage some common side effects:
Diarrhoea: Try taking your dose with food to minimise this effect.
Strange taste in the mouth: Consuming Crixan 500 Tablet with a meal might help mask this unusual taste.
The Crixan 500 Tablet contains clarithromycin (500 mg), which works on your body through distinct mechanisms:
Binds to Ribosomal Subunit: Clarithromycin connects with the 50S ribosomal subunit of susceptible bacteria. This part of a bacterium is responsible for protein synthesis which is crucial for their survival and growth.
Inhibits Protein Synthesis: By binding to the ribosomal subunit, clarithromycin interferes with aminoacyl translocation. This process involves moving the peptidyl tRNA from one site of the ribosome to another, effectively halting protein synthesis.
Bacteriostatic and Bactericidal Action: The inhibition of protein synthesis results in a bacteriostatic effect, meaning it prevents the bacteria from growing further. However, in high concentrations against highly susceptible organisms, clarithromycin can also be bactericidal, which means it can actively kill bacteria.
Broad Spectrum Activity: Clarithromycin has a broad spectrum of activity, which means it can act against various types of bacteria including gram-positive, gram-negative, anaerobic, and atypical bacteria. This makes Crixan 500 Tablet effective in managing a wide range of bacterial infections.
Caution is advised if you are pregnant. It is best to consult your doctor before taking this medicine.
Caution is advised while taking this medicine during breastfeeding. Consult your doctor to understand the potential risks and benefits.
Caution is advised when consuming alcohol while taking this medicine. Consult your doctor for guidance.
If you have mild to moderate liver impairment, caution should be exercised while taking Crixan 500 Tablet. This medicine may affect liver function, especially in severe conditions. Discuss with your doctor before starting this medication.
For those with a history of kidney problems, caution is recommended when using Crixan 500 Tablet. Make sure to consult your doctor before taking this medicine.
Crixan 500 Tablet might cause dizziness or confusion which could affect your ability to drive or operate machines. It's best to avoid such activities until you know how this medicine affects you.
If you are allergic to clarithromycin, erythromycin, or any macrolide antibiotic, you should not take Crixan 500 Tablet. Contact your doctor if you experience any allergic reactions.
It's advisable to consult a doctor before giving this medicine to children.
Older patients should take Crixan 500 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status, especially if you are above 70 years of age.
Crixan 500 Tablet interacts with the following medicines:
Anticoagulants: Medicines like warfarin may interact with Crixan 500 Tablet, potentially enhancing their anticoagulant effect.
Statins: When taken with Crixan 500 Tablet, statins like lovastatin and simvastatin can increase the risk of muscle damage.
Cardiac Medicines: Medicines like digoxin and pimozide may have increased levels due to interaction with Crixan 500 Tablet, leading to potential toxicity.
Crixan 500 Tablet can be taken with or without food. There are no specific food items that are known to interact with this medication.
Crixan 500 Tablet interacts with the following diseases:
Myasthenia gravis: Use of Crixan 500 Tablet could potentially worsen symptoms in patients suffering from myasthenia gravis, a condition that causes muscle weakness.
Heart disease: Patients with a history of ventricular arrhythmia or QT prolongation should use this medicine cautiously due to risk of further heart complications.
The daily dose of Crixan 500 Tablet should be taken as directed by your doctor. The dosage may vary depending on individual factors such as the severity of your condition and response to the medicine. Always follow the prescribed dosage and never exceed it without discussing with your doctor.
Taking too much of the Crixan 500 Tablet can lead to overdose symptoms such as stomach upset and hearing problems. If you suspect an overdose, inform your doctor to ensure appropriate measures are taken.
If you forget to take your Crixan 500 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Store your Crixan 500 Tablet below 30°C in a tightly closed container.
Keep the medicine protected from light and moisture.
Always keep it out of the reach of children.
It is crucial to use the medicine before its expiry date.
If you are taking Crixan 500 Tablet for respiratory infections, try to avoid smoke-filled environments and other irritants that may worsen your condition.
For those using it to manage dental infections or periodontitis, maintaining good oral hygiene, including regular brushing and flossing, can help in managing the condition better.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Respiratory Tract Infections, Skin Infections, Peptic Ulcer Disease |
| Drug Category | Protein Synthesis Inhibitor |
| Therapeutic Category | Antibiotic |
Crixan 500 Tablet is used to manage various bacterial infections such as respiratory tract, skin, ear, and dental infections. It can also help in eradicating H. pylori in ulcers.
The medicine works by binding to certain parts of bacteria and suppressing their protein synthesis. This disrupts their growth cycle, helping manage the infection effectively.
Yes, you can take Crixan 500 Tablet with or without food. However, always swallow it whole with a full glass of water for best absorption.
It may not be safe to use during pregnancy and breastfeeding. It should only be used if the benefits clearly outweigh potential risks after consulting your doctor.
If you've missed a dose, take it as soon as you remember unless it's nearly time for the next one. Don't double up doses to compensate.
Alcohol could enhance side effects like dizziness and stomach upset. It could also weaken your immune response so it's best avoided.
Generally, you may start feeling better within 2-3 days of starting the course but always complete the entire course to ensure complete management of the infection.
Check out Editorial Policy
BIAXIN. (n.d.). BIAXIN® FilmTab®. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050662s044s050,50698s026s030,050775s015s019lbl.pdf
Clarithromycin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01211
DailyMed - CLARITHROMYCIN tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=98580dee-d2f4-4f62-a2d4-7434bab2421e
Clarithromycin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a692005.html
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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