Cospiaq S 25 + 100 Tablet 10

Torrent Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹206.25~~

₹165

₹20.62/Units

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Composition

Empagliflozin (25 Mg) + Sitagliptin (100 Mg)

COSPIAQ S 25 + 100 TABLET 10 is prescribed as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It falls under a class of medications known as antidiabetics.

This tablet, when used in conjunction with a healthy diet and regular exercise, assists in achieving better blood sugar control. Maintaining optimal glycaemic levels is vital for preventing or delaying serious health conditions associated with diabetes, such as cardiovascular disease, kidney damage, nerve issues, and vision loss.

Before starting this medication, it is crucial to consult your doctor, who will prescribe the right dosage based on your condition. You should inform your doctor about any pre-existing health conditions or ongoing medications. If you experience any side effects while on this medicine, notify your doctor immediately.

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COSPIAQ S 25 + 100 TABLET 10 is used for:

Improving glycaemic control in adults with type 2 diabetes mellitus.

Swallow the tablet whole with water.
It can be taken with or without food, preferably at the same time every day.
Do not chew, crush, or split the tablet.
Always follow your doctor’s instructions regarding timing and dosage.

COSPIAQ S 25 + 100 TABLET 10 is taken orally.

COSPIAQ S 25 + 100 TABLET 10 may cause the following common side effects:

Vaginal yeast infections or other genital infections
Urinary tract infections
Increased urination
Constipation
Rash or itching

Management Of Side Effects:

Most side effects are temporary, generally harmless, and resolve upon discontinuing the use of COSPIAQ S 25 + 100 TABLET 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Urinary tract infections: Drink sufficient water, maintain hygiene, and seek medical help if you develop burning urination, fever, or back pain.
Genital infections: Keep the area clean and dry. Antifungal treatment may be prescribed if infections persist.
Dehydration from increased urination: Increase your fluid intake and avoid excessive alcohol and caffeine.
Constipation: Eat high-fibre foods, drink plenty of fluids, and stay physically active.

COSPIAQ S 25 + 100 TABLET 10 contains the following components:

Empagliflozin (25 mg): A sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by blocking SGLT2 in the kidneys, leading to increased removal of glucose through urine, thereby lowering blood sugar levels.
Sitagliptin (100 mg): A dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing incretin levels in the body, which improve insulin release after meals and reduce glucose production by the liver.

Pregnancy

COSPIAQ S 25 + 100 TABLET 10 is not recommended during pregnancy. Its safety has not been established, and animal studies suggest possible risks to the baby. Always consult your doctor for safer alternatives.

Breastfeeding

It is not known whether empagliflozin or sitagliptin passes into human breast milk. Animal studies show both components may appear in milk. To avoid potential risk to the infant, breastfeeding mothers should not use this medicine unless specifically advised by a doctor.

Alcohol

Alcohol may cause fluctuations in blood sugar levels, increase the risk of dehydration, and raise the risk of lactic acidosis. Avoid or limit alcohol consumption during treatment.

Liver

COSPIAQ S 25 + 100 TABLET 10 should be used with caution in patients with liver impairment. Severe liver disease may worsen side effects or change how the medicine works in the body.

Kidney

COSPIAQ S 25 + 100 TABLET 10 is not recommended for patients with severe kidney impairment or those on dialysis. Kidney function should be checked before starting treatment with this tablet.

Use In Driving And Operating Machinery

This medicine may cause dizziness, tiredness, or blurred vision, particularly if your blood sugar is too low or too high. Do not drive or operate machinery until you know how the medicine affects you.

Allergy

Do not use COSPIAQ S 25 + 100 TABLET 10 if you are allergic to empagliflozin, sitagliptin, or any other ingredient in the formulation.

Children

This medicine is not recommended for patients under 18 years of age, as safety and effectiveness have not been established in this group.

Older Patients

Patients aged over 70 years may have a higher risk of dehydration, kidney problems, and low blood pressure. Regular monitoring is necessary, and the medicine should only be used under close medical supervision.

Drug-Drug Interactions

COSPIAQ S 25 + 100 TABLET 10 interacts with the following medicines:

Diuretics such as furosemide: The concomitant use may increase the risk of dehydration or low blood pressure when combined with COSPIAQ S 25 + 100 TABLET 10.
Insulin and sulphonylureas (such as glimepiride): Increase the risk of low blood sugar. Your doctor may lower the dose of these medicines.
Antibiotics such as rifampin: May reduce the effectiveness of sitagliptin.
Corticosteroids such as prednisone and sympathomimetics such as epinephrine, albuterol: The concomitant use may make blood sugar harder to control.
UGT enzyme inducers (such as phenytoin or rifampicin): The concomitant use may reduce the effect of empagliflozin. Co-administration is not recommended.

Drug-Disease Interactions

COSPIAQ S 25 + 100 TABLET 10 interacts with the following diseases:

Pancreatitis: Patients with a history of pancreatitis should avoid this medicine as sitagliptin may increase the risk.
Kidney impairment: Reduced kidney function lowers the effectiveness of empagliflozin and may increase the risk of adverse effects. Discontinue if kidney function worsens.
Ketoacidosis: Rare cases have been reported. Patients with symptoms such as nausea, vomiting, abdominal pain, or unusual tiredness should stop treatment and seek urgent medical help.

Daily Dose

The recommended daily dose of COSPIAQ S 25 + 100 TABLET 10 should be taken as per your doctor’s advice. The dosage may vary depending on the severity of your condition and your response to treatment. Never change the dose without consulting your doctor.

Over Dose

Taking more than the prescribed dose of COSPIAQ S 25 + 100 TABLET 10 may cause severe dehydration, dizziness, increased urination, or low blood sugar. Seek medical help immediately.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose.

Store in a cool, dry place away from sunlight and moisture.
Keep out of the reach of children.
Do not use after the expiry date printed on the packaging.

Follow a balanced diet with reduced sugar and refined carbohydrates.
Eat more vegetables, whole grains, lean proteins, and fibre-rich foods.
Stay well hydrated to reduce the risk of dehydration.
Exercise regularly, as advised by your doctor, to improve blood sugar control.
Monitor your blood sugar levels regularly and keep scheduled follow-up appointments.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 diabetes mellitus
Drug Category	SGLT2 inhibitor + DPP-4 inhibitor
Therapeutic Category	Antidiabetics

What is COSPIAQ S 25 + 100 TABLET 10 used for?

It is used to improve blood sugar control in adults with type 2 diabetes mellitus and to help reduce the risk of complications such as heart disease.

How does COSPIAQ S 25 + 100 TABLET 10 work?

It contains empagliflozin, which removes extra sugar through urine, and sitagliptin, which helps regulate insulin release and reduces sugar production by the liver.

Can I take COSPIAQ S 25 + 100 TABLET 10 during pregnancy?

No, it is not recommended during pregnancy. Please consult your doctor for safer alternatives.

Does COSPIAQ S 25 + 100 TABLET 10 cause low blood sugar?

When used alone, the risk of low blood sugar is low. However, when combined with insulin or sulphonylureas, the risk of low blood sugar increases.

Can elderly patients take COSPIAQ S 25 + 100 TABLET 10?

Yes, but with caution. Older patients are at greater risk of dehydration and kidney problems. Regular monitoring is important.

Last Updated On 15 Sep. 2025 | 6:02AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 10 years

PhD in Chemistry

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 11 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

Torrent House, Off. Ashram Road, Ahmedabad - 380009, Gujarat, India

Country of origin: INDIA

Expiry on or after: November 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

EMPAZIO S 25+100. (N.d.). Torrentpharma.Com. Retrieved August 25, 2025, from https://www.torrentpharma.com/assets/Empazio_S_PI_33638c5900.pdf
Empagliflozin: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a614043.html
Empagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09038
JANUVIA® (sitagliptin) Tablets. (N.d.). Fda.Gov. Retrieved August 25, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021995s019lbl.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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