Apristar 125/80 Capsule 3

Lupin Ltd

Strip of 3 Units

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Old MRP ₹1300

MRP ~~₹1218.75~~

₹975

₹406.25/Units

20% off

*MRP inclusive of all taxes

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15 days Easy returns

Prescription required for this medicine

Store Below 30° C

Composition

Aprepitant (80 Mg)

Apristar 125/80 Capsule 3 is used to prevent nausea and vomiting associated with chemotherapy. It belongs to the class of medicines known as antiemetics (neurokinin-1 receptor antagonists).

This medicine is commonly prescribed to people undergoing moderate to highly emetogenic chemotherapy. It helps reduce the severity and frequency of nausea and vomiting caused by cancer treatment, supporting better comfort and adherence to therapy.

Take this medicine exactly as prescribed. Inform your doctor about any existing medical conditions, including liver problems, and share details of all other medicines you are taking. Continue the full course as advised, even if symptoms improve early.

Apristar 125/80 Capsule 3 is used to:

Prevent nausea and vomiting associated with chemotherapy
Prevent postoperative nausea and vomiting

Follow these instructions while taking Apristar 125/80 Capsule 3:

Take the capsule exactly as prescribed by your doctor.
Swallow the capsule whole with water.
It may be taken with or without food.
Take it at the same time each day as advised by your doctor.
Follow the duration of treatment exactly as prescribed.
Do not stop the medicine suddenly or take extra doses without medical advice.

Apristar 125/80 Capsule 3 is taken orally.

Apristar 125/80 Capsule 3 may cause side effects, such as:

Fatigue or tiredness
Loss of appetite
Constipation
Diarrhoea
Headache
Dizziness

Management Of Side Effects:

Most side effects of Apristar 125/80 Capsule 3 are usually mild and improve as your body adjusts to the medicine. However, if any symptom becomes severe or does not go away, contact your doctor.

Here are some general tips:

Fatigue or tiredness: Rest when needed and avoid overexertion. Take short breaks during the day to manage tiredness.
Constipation: Drink plenty of water, eat fibre-rich foods, and consider light physical activity if approved by your doctor.

Apristar 125/80 Capsule 3 contains the following active component:

Aprepitant (80 mg): This medicine works by blocking neurokinin-1 (NK1) receptors in the brain, which play a role in triggering nausea and vomiting. By preventing these signals, it helps reduce the frequency and severity of nausea and vomiting.

Pregnancy

Apristar 125/80 Capsule 3 is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Breastfeeding

Consult your doctor before taking Apristar 125/80 Capsule 3 while breastfeeding. Limited data is available on whether this medicine passes into breast milk.

Alcohol

Avoid excessive alcohol consumption while taking Apristar 125/80 Capsule 3, as it may increase fatigue, dizziness, or gastrointestinal discomfort.

Liver

If you have liver problems, inform your doctor before starting Apristar 125/80 Capsule 3. Dose adjustment or monitoring may be required.

Kidney

Apristar 125/80 Capsule 3 is generally safe, but tell your doctor if you have kidney issues.

Use In Driving And Operating Machinery

Some people may feel tired or dizzy. Avoid driving or using machines until you know how this medicine affects you.

Allergy

Do not take Apristar 125/80 Capsule 3 if you are allergic to aprepitant or any other ingredients in the capsule. Seek immediate medical help if you experience rash, swelling, or difficulty breathing.

Children

Apristar 125/80 Capsule 3 can be prescribed in children when advised by a doctor. The dose is adjusted based on age, body weight, and clinical condition. Always follow the doctor’s instructions regarding dosing and monitoring.

Older Patients

Older patients should take this medicine under medical supervision, as they may be more sensitive to side effects such as tiredness, dizziness, or stomach discomfort.

Drug-Drug Interactions

Apristar 125/80 Capsule 3 may interact with the following medicines:

Antiepileptic medicines (phenytoin, carbamazepine): These medicines decrease the effect of Apristar 125/80 Capsule 3 by increasing its breakdown in the body.
Antitubercular medicines (rifampicin): Strongly reduce the effectiveness of Apristar 125/80 Capsule 3 by increasing its breakdown in the body. This combination should generally be avoided. Consult your doctor if both medicines are prescribed.
Other medicines affected by liver enzymes (CYP3A4): Apristar 125/80 Capsule 3 can increase or decrease the levels of certain medicines such as dexamethasone, warfarin, and midazolam. Your doctor may adjust doses or monitor therapy closely.
Hormonal contraceptives (birth control pills, patches, implants, injections): This medicine can reduce the effectiveness of hormonal birth control methods. Your doctor may advise using additional non-hormonal contraception during treatment and for the recommended duration after stopping the medicine.

Drug-Disease Interactions

Apristar 125/80 Capsule 3 may require caution in certain medical conditions:

Liver disease: This medicine is metabolised in the liver. In people with moderate to severe liver impairment, the medicine may stay longer in the body, which can increase the risk of side effects. Your doctor may monitor liver function and adjust the dose if needed.
Severe hepatic impairment (Child-Pugh Class C): In people with severe liver impairment (Child-Pugh Class C), the medicine may remain in the body longer than expected, leading to higher drug levels and an increased risk of side effects. Because safety data in this group is limited, this medicine should be used with caution or avoided unless clearly advised by a doctor. If prescribed, close medical supervision and monitoring for side effects may be required.

Daily Dose

Take Apristar 125/80 Capsule 3 exactly as prescribed by your doctor. Follow the schedule and instructions provided to prevent nausea and vomiting during chemotherapy. The medicine is usually taken alongside other anti-nausea medicines as recommended by your healthcare provider.

Over Dose

Taking more than the prescribed dose of Apristar 125/80 Capsule 3 may increase the risk of side effects such as dizziness, fatigue, or stomach discomfort. Contact your doctor or seek medical help immediately if you experience unusual symptoms.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one. Do not take extra capsules to make up for a missed dose.

Store Apristar 125/80 Capsule 3 in its original packaging.
Keep in a cool, dry place away from heat and moisture.
Keep out of reach of children.
Do not use it after the expiry date printed on the pack.

Stay well hydrated: Drink plenty of fluids throughout the day to help reduce fatigue and support overall body function during chemotherapy.
Eat small, frequent meals: Eating smaller portions more often may help manage nausea and maintain energy levels.
Choose bland, easy-to-digest foods: Foods like rice, toast, bananas, and oatmeal may be easier on the stomach if you feel nauseated.

Fact Box

Dosage Forms Available	Capsule
Habit Forming	No
Ailment	Nausea and vomiting associated with chemotherapy or surgery
Drug Category	Antiemetic
Therapeutic Category	NK1 receptor antagonist

What is Apristar 125/80 Capsule 3 used for?

Apristar 125/80 Capsule 3 is used to prevent nausea and vomiting caused by chemotherapy. It is often taken along with other anti-nausea medicines to protect against both early and delayed nausea.

How does Apristar 125/80 Capsule 3 work?

This medicine blocks a chemical in the body called substance P, which triggers nausea and vomiting. By doing so, it helps reduce how often and how severely you feel sick during chemotherapy.

Can I stop taking Apristar 125/80 Capsule 3 once I feel better?

No. Continuing the full course as prescribed is important to ensure maximum prevention of nausea and vomiting throughout your chemotherapy treatment.

Is Apristar 125/80 Capsule 3 safe during pregnancy or breastfeeding?

This medicine should be taken during pregnancy or breastfeeding only if clearly advised by the doctor, after assessing the risks and benefits.

Can Apristar 125/80 Capsule 3 affect my birth control?

Yes. Apristar 125/80 Capsule 3 can reduce the effectiveness of hormonal birth control, including pills, injections, implants, patches, and vaginal rings. To prevent pregnancy while taking this medicine, it is advised to use barrier methods, such as condoms, diaphragms, cervical caps, spermicides, or contraceptive sponges. Continue using these methods during treatment and for the time your doctor recommends.

Last Updated On 23 Feb. 2026 | 2:58PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead & Reviewer | 7 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 12 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

Expiry on or after: October 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). Aprepitant capsule; aprepitant kit. U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f58b8944-93ee-4be1-a238-cc0061ddd93a
MedlinePlus. (n.d.). Aprepitant. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a604003.html
National Center for Biotechnology Information. (n.d.). Aprepitant. PubChem Compound Summary. https://pubchem.ncbi.nlm.nih.gov/compound/Aprepitant
Nausea and vomiting and cancer - side effects. (2025, May 9). Cancer.gov. https://www.cancer.gov/about-cancer/treatment/side-effects/nausea-vomiting

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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