Acefile Sr 200 Tablet 10

Ajanta Pharma Ltd

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MRP ~~₹82.96~~

₹66.37

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Composition

Aceclofenac (200 Mg)

Acefile SR 200 Tablet is used to manage pain and inflammation linked to chronic joint and musculoskeletal conditions. It contains aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), in a sustained-release form.

This medicine helps relieve symptoms of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, while also providing short-term relief from pain, stiffness and swelling in various musculoskeletal disorders. Swallow the tablet whole with water, preferably with food, as prescribed by your doctor.

Staying gently active within your comfort level and applying a warm compress to stiff joints can support relief alongside this medicine.

Tell your doctor about any other medicines or underlying health issues, such as kidney or liver disease, before starting treatment. This medicine is not recommended in the third trimester of pregnancy. Report persistent stomach pain or unusual bruising to your doctor promptly, and do not stop taking the medicine without medical advice.

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Acefile SR 200 Tablet is used to manage pain and inflammation in chronic joint conditions such as rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, and for short-term relief of musculoskeletal pain and stiffness.

Uses of Acefile SR 200 Tablet are:

Rheumatoid Arthritis and Osteoarthritis: Relieves joint pain, stiffness and swelling.
Ankylosing Spondylitis: Eases inflammation and stiffness in the spine and joints.
Short-Term Musculoskeletal Pain: Provides relief from pain and swelling in other joint or muscle conditions.

Swallow the tablet whole with a glass of water. Avoid crushing or chewing it.
It's best to take this medicine with food to minimise potential stomach discomfort.
Always take the medicine in the dosage and frequency prescribed by your doctor.
Stopping this medicine abruptly may lead to withdrawal symptoms. Always consult your doctor before discontinuing use.

Acefile Sr 200 Tablet 10 is taken orally.

Acefile SR 200 Tablet may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few Common Side Effects of Acefile SR 200 Tablet:

Digestive: Nausea, vomiting, diarrhoea, stomach upset, indigestion and abdominal pain.
Neurological: Headache and dizziness.

If side effects do not improve or become serious, stop taking the medicine and speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can also effectively manage common side effects like nausea, vomiting, diarrhoea, or abdominal pain at home by taking the medicine with food or after your meals.

Acefile Sr 200 Tablet 10 contains aceclofenac (200 mg) as the main ingredient. It works in the human body in the following manner:

Aceclofenac blocks the cyclo-oxygenase enzyme, which is responsible for producing prostaglandins. Prostaglandins are chemical substances that trigger pain, inflammation, and fever in your body.
Aceclofenac also affects the central nervous system, modifying how you perceive pain and providing effective relief from pain.

Pregnancy

Acefile Sr 200 Tablet 10 is contraindicated in pregnancy, especially during the third trimester. If you are pregnant or planning to conceive, it is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised before taking this medicine while breastfeeding, as aceclofenac may pass into breast milk and affect your baby. Always consult your doctor before starting this medicine.

Alcohol

Avoid consuming alcohol while taking this medicine as it may increase the risk of side effects such as dizziness or stomach bleeding. Always consult your doctor regarding alcohol intake.

Liver

This medicine is contraindicated in patients with severe liver disease or liver failure. If you have any liver issues, discuss them with your doctor before starting this medicine.

Kidney

Patients with severe renal impairment or kidney failure are contraindicated from using this medicine as it may worsen their condition. Always consult your doctor for advice.

Use In Driving And Operating Machinery

Acefile Sr 200 Tablet 10 may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how this medicine affects you.

Allergy

If you have a history of allergic reactions to NSAIDs or any other component of Acefile Sr 200 Tablet 10, avoid its use. Always discuss your allergies with your doctor.

Children

This medicine is meant for adults and is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Elderly patients (≥65 years) may be more susceptible to the side effects of the medicine and should, therefore, take it under medical supervision. Your doctor will determine the dosage based on your condition.

Drug-Drug Interactions

Acefile Sr 200 Tablet 10 may interact with the following medications:

Anticoagulants: Medicines like warfarin and heparin, when taken with Acefile Sr 200 Tablet 10, can increase the risk of bleeding.
Diuretics: Medications such as furosemide and hydrochlorothiazide, when used with this tablet, can have their effects reduced, leading to possible kidney damage.
Mood stabilisers such as lithium: Consuming lithium-based medicines along with this tablet could lead to increased lithium levels in the body, causing adverse effects.
Beta-blockers: This medicine when taken with beta-blockers like atenolol and metoprolol can reduce the blood pressure-lowering capability of these medications.
Other NSAIDs: When used in combination with other NSAIDs such as ibuprofen or naproxen, there is an escalated risk of stomach problems and bleeding.

Drug-Food Interactions

None

Drug-Disease Interactions

Acefile Sr 200 Tablet 10 may interact with the following diseases:

Gastrointestinal disorders: If you have a history of stomach ulcers or bleeding, this medicine is contraindicated.
Renal impairment: Those with severe kidney problems are contraindicated from taking this medicine as it may worsen their condition.
Liver disease: Patients with severe liver disease or liver failure are also contraindicated from taking this medicine as it could exacerbate their condition.
Cardiovascular conditions: If you have heart disease or are at risk for heart-related events, this medicine may amplify these risks and, hence is contraindicated.

Daily Dose

Take your dose of Acefile Sr 200 Tablet 10 as prescribed by your doctor. The dosage could vary depending on factors like the severity of your condition and how you respond to the medicine.

Over Dose

In case of an overdose, you may experience common side effects like stomach pain, nausea, or dizziness. If you notice these or any other unusual symptoms, inform your doctor promptly.

Missed Dose

If you missed a dose of the medicine, take it as soon as you remember. However, if it's nearly time for the next dose, skip the one you missed and continue with your regular schedule. Never increase the dose without discussing it with your doctor.

Store Acefile Sr 200 Tablet 10 in a cool, dry place, at room temperature below 30°C.
Keep the medicine away from direct light and moisture.
Always keep this medicine out of reach of children.
Ensure to use the medicine before its expiry date.

A balanced diet rich in calcium and vitamin D can help manage conditions like arthritis or ankylosing spondylitis. These nutrients support bone health.
Regular low-impact exercise, such as swimming or cycling, can help maintain joint flexibility and reduce stiffness. However, remember to consult your doctor before starting any new exercise regime.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis
Drug Category	NSAIDs
Therapeutic Category	Anti-Inflammatory

What is Acefile Sr 200 Tablet 10 used for?

Acefile Sr 200 Tablet 10 is used to manage pain and inflammation linked to various forms of arthritis and ankylosing spondylitis.

How does Acefile Sr 200 Tablet 10 work?

This medicine contains aceclofenac, an NSAID that reduces the production of prostaglandins in the body that cause pain and inflammation, thus providing relief.

How should I take Acefile Sr 200 Tablet 10?

You should swallow this tablet with water, preferably with food to lower the risk of stomach-related side effects. Always take the medicine in the dosage and frequency prescribed by your doctor.

Can anyone take Acefile Sr 200 Tablet 10?

No, people with certain health conditions like severe liver, kidney, or heart conditions are contraindicated from taking this medicine. Always consult your doctor before starting this medication.

Are there any side effects of Acefile Sr 200 Tablet 10?

Yes, the common side effects of the medicine include nausea, abdominal pain, diarrhoea, and dizziness. If these symptoms persist or worsen, consult your doctor immediately.

Can I drink alcohol while taking Acefile Sr 200 Tablet 10?

Alcohol consumption while taking this medicine may increase the risk of side effects such as dizziness or stomach bleeding. It's advisable to avoid alcohol when on this medication.

How should I store Acefile Sr 200 Tablet 10?

Store the tablet in a cool, dry place away from light and moisture. For safety, keep out of the reach of children and pets.

Last Updated On 22 Sep. 2026 | 11:32AM (IST)

Certified Content

Written by

Pragati Bhosale

Medical Content Reviewer | 5 years

M. Pharmacy

Reviewed by

Dr. Nikhil Sharma

Medical Content Writer | 6 years

M.S Orthopaedics

Check out Editorial Policy

Manufacturer details

54, Sir Mathuradas Vasanji Rd, Hanuman Nagar, Andheri East, Mumbai, Maharashtra 400053

Country of origin: INDIA

Expiry on or after: March 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

PubChem. (n.d.-a). Aceclofenac. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac
DailyMed - CLANZA CR- aceclofenac tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3
Medicines and Healthcare products Regulatory Agency. (2015, January 22). Aceclofenac (Preservex): updated cardiovascular advice in line with diclofenac and COX-2 inhibitors. GOV.UK. https://www.gov.uk/drug-safety-update/aceclofenac-preservex-updated-cardiovascular-advice-in-line-with-diclofenac-and-cox-2-inhibitors
A Review of Aceclofenac: Analgesic and Anti-Inflammatory Effects on Musculoskeletal Disorders. (2021, November 30). ncbi.nlm.nih.gov. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643213/
Aceclofenac: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06736
Aceclofenac. (2006). In Meyler’s Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (p. 11). Elsevier. https://www.sciencedirect.com/science/article/abs/pii/B0444510052012274?via%3Dihub

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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