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CompositionSyndopa CR Tablet is used to manage Parkinson’s disease symptoms by increasing dopamine levels in the brain. It helps improve movement, reduce tremors, and relieve stiffness, allowing patients to maintain better motor control and daily functioning.
Apart from treating Parkinson’s disease, this tablet is also effective in managing post-encephalitic parkinsonism and symptomatic parkinsonism caused by nervous system injuries, including those from carbon monoxide or manganese exposure.
Syndopa CR Tablet is used to treat Parkinson’s disease symptoms like tremors, stiffness, and slow movements. It contains Levodopa and Carbidopa, which increase dopamine levels in the brain to improve muscle control. This medicine also helps manage parkinsonism caused by brain infections, carbon monoxide poisoning, or manganese exposure.
Swallow the tablet whole with water.
Refrain from crushing or chewing the tablet.
Aim to take this medicine at the same time each day to maintain a consistent level in your body.
You can take this medicine with or without food. If you feel nauseous, taking it with food may help.
Remember not to consume high-protein meals or iron supplements around the same time as this medicine, as they might interfere with its absorption.
Always consult your doctor before altering the dosage or stopping the medicine
Syndopa CR Tablet is taken orally.
Syndopa CR Tablet may cause side effects like abnormal movements (dyskinesias), nausea, dizziness, headache, dry mouth. Other possible effects include dystonia, which involves sustained muscle contractions and repetitive movements, and somnolence, characterized by excessive sleepiness or a strong desire to sleep.
Nausea: Try taking Syndopa CR Tablet with food to help alleviate this.
Dizziness: Consider taking your medicine at night if it causes you to feel dizzy during the day.
Syndopa CR Tablet consists of two components:
Carbidopa (50 mg): Carbidopa does not cross into your brain. It works by blocking the conversion of levodopa into dopamine in other parts of your body. This reduces side effects like nausea and vomiting and allows a greater amount of levodopa to enter your brain.
Levodopa (200 mg): Unlike dopamine, levodopa can cross into your brain. Once it is in there, it gets converted into dopamine by an enzyme called DOPA decarboxylase. This increase in brain dopamine levels helps manage symptoms of Parkinson's disease.
Caution is advised while taking Syndopa CR Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.
If you are breastfeeding, it's important to discuss with your doctor before starting Syndopa CR Tablet.
It's advisable to limit alcohol consumption while taking Syndopa CR Tablet. High alcohol intake might interfere with the medicine's efficacy.
If you have a history of liver problems, it's recommended to talk to your doctor before starting Syndopa CR Tablet. This medicine may affect liver function.
If you've had kidney health issues in the past, caution is advised while taking Syndopa CR Tablet. Consult your doctor for advice tailored to your health status.
Syndopa CR Tablet may cause dizziness or somnolence. It's advisable not to drive or operate heavy machinery until you know how this medicine affects you.
If you're allergic to any component of Syndopa CR Tablet, avoid using this medicine. Discuss with your doctor for alternative options.
Syndopa CR Tablet is not typically recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should use Syndopa CR Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Dopamine D2 Receptor Antagonists: Medicines such as phenothiazines, butyrophenones, and risperidone may decrease the effectiveness of Levodopa in Syndopa CR Tablet.
Nonselective Monoamine Oxidase (MAO) Inhibitors: The use of selegiline, and tranylcypromine is contraindicated with Syndopa CR Tablet due to potential severe interactions.
Iron salts: These can reduce the amount of Levodopa available to your body when taken alongside Syndopa CR Tablet.
Eating a high-protein diet could reduce the effectiveness of Syndopa CR Tablet. It's recommended to distribute your daily protein intake so that most of it is consumed in the evening meal.
Neuroleptic Malignant Syndrome (NMS) or Akinetic Crisis: Abrupt withdrawal or dose reduction of Syndopa CR Tablet could trigger these conditions.
Myocardial Infarction or Arrhythmias: Patients with a history of these heart conditions should exercise caution while taking this medication.
Narrow-Angle Glaucoma: This medicine should not be used by patients with this eye condition due to potential severe complications.
Skin Lesions or Melanoma: Regular monitoring for melanoma is advised for patients with suspicious undiagnosed skin lesions or a history of melanoma while taking this medication.
The daily dose of Syndopa CR Tablet should be consumed as advised by your doctor. The dosage may vary based on individual responses and the severity of your condition. Always adhere to your doctor's instructions and avoid exceeding the recommended dosage.
If you accidentally consume more Syndopa CR Tablet than your prescribed dose, you may experience increased side effects such as nausea, dizziness, or abnormal involuntary movements. If these symptoms persist or worsen, consult your doctor.
In case you forget to take Syndopa CR Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular dosing schedule. Never increase your dose without consulting your doctor.
Keep Syndopa CR Tablet in a dry place, away from light and moisture.
The optimal storage temperature is below 25°C.
Always ensure the medicine is out of reach of children.
Remember to use the medicine before its expiry date.
To help manage Parkinson's disease, try performing gentle exercises like yoga or Tai Chi. These might help improve your balance, flexibility, and muscle strength.
A balanced diet is crucial. However, large amounts of protein may affect how this medicine works. Try to consume most of your daily protein in the evening meal.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Parkinson's Disease, Post-Encephalitic Parkinsonism |
| Drug Category | Dopamine Precursor |
| Therapeutic Category | Antiparkinsonian |
Syndopa CR Tablet contains levodopa and carbidopa. Levodopa is converted to dopamine in the brain, helping manage symptoms of Parkinson's disease. Carbidopa reduces side effects by ensuring more levodopa reaches the brain.
Take Syndopa CR Tablet exactly as prescribed by your doctor.
If you have a history of heart problems, glaucoma, skin lesions, or severe disease such as asthma or kidney disease, consult your doctor before starting Syndopa CR Tablet.
Avoid high-protein meals and iron supplements while taking Syndopa CR Tablet as they may interfere with levodopa absorption. Distribute protein intake throughout the day for better effectiveness.
No, the tablets should be swallowed whole without crushing or chewing to maintain the extended-release properties.
Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular schedule.
No, Syndopa CR Tablet does not cure Parkinson's disease but helps manage its symptoms effectively. Always consult your doctor before making any changes to your medication regimen.
Check out Editorial Policy
NDA 17-555/S-069. (2000). SINEMET (CARBIDOPA-LEVODOPA) TABLETS. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/017555s069lbl.pdf
Riverside Pharmaceuticals. (1975). DHIVY (carbidopa and levodopa) tablets, for oral use. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/214869s000lbl.pdf
AbbVie Inc. (2020). DUOPA [Prescribing information]. In DUOPA. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/203952s011lbl.pdf
Highlights of prescribing information. (2015). https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/203952s000lbl.pdf
DailyMed - CARBIDOPA AND LEVODOPA tablet, extended release. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=11587fa6-dc2c-44a5-85c6-85ec40c6b9b1
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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