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CompositionSyndopa CR 125 Tablet is used to manage symptoms of Parkinson’s disease, including tremors, muscle stiffness, and slowed movements. It helps restore dopamine balance in the brain, improving motor control and daily functioning.
This medicine is also useful in Parkinsonian syndromes and movement disorders. Take it strictly as prescribed, and do not alter the dose without medical advice. Regular use helps maintain smoother movement control.
Syndopa CR 125 Tablet is used to manage symptoms of Parkinson’s disease by increasing dopamine levels in the brain. It helps improve motor control and reduces symptoms such as tremors, muscle stiffness, and slowness of movement (bradykinesia), enabling better coordination and improved daily functioning.
Here are some instructions to follow while taking Syndopa CR 125 Tablet:
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always take this medicine at the same time each day to maintain steady levels in your body.
Consult your doctor if you are unsure about any aspect of using this medicine.
Syndopa CR 125 Tablet is taken orally.
Syndopa CR 125 Tablet may cause side effects including sweating, dry mouth, dizziness, headache, abnormal dreams, nausea, vomiting, loss of appetite, and uncontrolled movements. In some cases, serious side effects like severe dizziness, fainting, hallucinations, confusion, fever, muscle stiffness, or unusual body movements may occur and require immediate medical attention. If any of these side effects persist or worsen, consult your healthcare provider.
Most side effects are temporary and generally harmless that resolve on discontinuing the use of Syndopa CR 125 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Dryness of mouth: Sipping water regularly can alleviate this effect.
Gastrointestinal disturbances: Taking Syndopa CR 125 Tablet with a light meal may lessen these effects.
Syndopa CR 125 Tablet contains two active ingredients:
Carbidopa (25 mg): Carbidopa acts by inhibiting an enzyme known as DOPA decarboxylase, found in peripheral tissues. By doing so, it prevents levodopa from being broken down before it reaches the brain, which allows more levodopa to be available in the brain.
Levodopa (100 mg): Once inside the brain, levodopa gets converted into dopamine, a neurotransmitter that plays a vital role in coordinating movements. In Parkinson's disease, there is a deficiency of dopamine in certain parts of the brain; levodopa helps replenish these levels, improving motor functions.
The extended-release formulation of Syndopa CR 125 ensures a steady supply of these active ingredients over several hours.
Caution is advised while taking Syndopa CR 125 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.
Syndopa CR 125 Tablet may suppress lactation partially or completely. If you are breastfeeding, it's best to discuss this with your doctor before starting this medication.
Avoid alcohol while taking Syndopa CR 125 Tablet as it can exacerbate dizziness and drowsiness caused by the medicine.
It's advisable to discuss any liver-related concerns with your doctor before starting Syndopa CR 125 Tablet.
Caution is advised before using Syndopa CR 125 Tablet if you have a history of kidney problems. It's a good idea to discuss this with your doctor before starting the medication.
Exercise caution while driving or operating machinery, as Syndopa CR 125 Tablet may cause sudden drowsiness and affect alertness.
Syndopa CR 125 Tablet should not be given to patients with known hypersensitivity to any component of the product. If you have experienced allergic reactions in the past, do inform your doctor.
Caution is advised while giving Syndopa CR 125 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Syndopa CR 125 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.
Syndopa CR 125 Tablet interacts with the following medicines:
MAO inhibitors: Taking Syndopa CR 125 Tablet along with MAO inhibitors like rasagiline and selegiline can cause a dangerous rise in blood pressure.
Antipsychotics: Medicines like chlorpromazine, haloperidol, and risperidone, can interfere with the action of Syndopa CR 125 Tablet, reducing its effectiveness.
Antihypertensives: These medicines, such as amlodipine, may interact with Syndopa CR 125 Tablet, potentially leading to excessively low blood pressure or hypotension.
Certain dietary items interact with Syndopa CR 125 Tablet.
High-protein foods: Consumption of high-protein foods can interfere with the absorption of levodopa in Syndopa CR 125 Tablet, reducing its effectiveness.
Syndopa CR 125 Tablet interacts with the following diseases:
Narrow-angle glaucoma: This medicine could worsen the condition of people suffering from narrow-angle glaucoma.
Severe psychosis or dementia: Symptoms of these conditions can be exacerbated by Syndopa CR 125 Tablet.
The daily dose of Syndopa CR 125 Tablet should be taken as directed by your doctor. Based on factors like your condition's severity and your response to the medication, the dosage may change. You must adhere to your doctor's prescribed dosage and never exceed it without medical advice.
In instances where an overdose of Syndopa CR 125 Tablet occurs, you might experience symptoms like dizziness, headache or gastrointestinal disturbances. If such symptoms occur, ensure you notify your doctor without delay.
If a dose of Syndopa CR 125 Tablet is missed, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and resume following your regular schedule. Never adjust your dosage without consulting with your doctor.
Store Syndopa CR 125 Tablet at room temperature, ideally not exceeding 25°C.
Keep the product away from direct light, heat, and moisture to maintain its effectiveness.
Always keep this medicine out of the reach and sight of children.
It's important to use Syndopa CR 125 Tablet before the expiration date printed on the pack.
Limit protein-rich foods like meat, fish, and dairy products. High protein diets can interfere with the absorption of levodopa, an active ingredient in Syndopa CR 125 Tablet, making it less effective in managing Parkinson's symptoms.
Be aware that sudden movements or changes in position can lead to a drop in blood pressure (orthostatic hypotension). So, make sure you rise slowly from a sitting or lying position to prevent dizziness or fainting.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Parkinson's disease, Parkinson's syndrome |
| Drug Category | Dopamine Precursor |
| Therapeutic Category | Antiparkinsonian |
Syndopa CR 125 Tablet is used to manage the symptoms of Parkinson's disease and related movement disorders.
It replenishes dopamine levels in the brain, improving motor functions and reducing symptoms like tremors and stiffness.
No, it doesn't cure Parkinson's. It manages the symptoms but can't cure the underlying condition, which is chronic and progressive.
The tablet is meant for oral administration. It should be swallowed whole, without crushing or chewing.
If you miss a dose, take it as soon as you remember, unless it's nearly time for your next dose.
Avoid a high-protein diet and limit dairy products. Also, don't take it with iron supplements or multivitamins containing iron.
Common side effects include dry mouth, dizziness, abnormal dreams, involuntary muscle movements, gastrointestinal disturbances like nausea and vomiting, and sweating.
Check out Editorial Policy
Riverside Pharmaceuticals. (1975). DHIVY (carbidopa and levodopa) tablets, for oral use. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/214869s000lbl.pdf
NDA 17-555/S-069. (2000). SINEMET (CARBIDOPA-LEVODOPA) TABLETS. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/017555s069lbl.pdf
Carbidopa: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00190
Levodopa: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01235
Block, G., Liss, C., Reines, S., Irr, J., & Nibbelink, D. (1997). Comparison of Immediate-Release and Controlled Release Carbidopa/Levodopa in Parkinson’s Disease. European Neurology, 37(1), 23–27. https://doi.org/10.1159/000117399
Allen, R. P., & Earley, C. J. (1996). Augmentation of the restless legs syndrome with Carbidopa/Levodopa. Sleep, 19(3), 205–213. https://doi.org/10.1093/sleep/19.3.205
LeWitt, P. A., Giladi, N., & Navon, N. (2019). Pharmacokinetics and efficacy of a novel formulation of carbidopa-levodopa (Accordion Pill®) in Parkinson’s disease. Parkinsonism & Related Disorders (Online)/Parkinsonism & Related Disorders, 65, 131–138. https://doi.org/10.1016/j.parkreldis.2019.05.032
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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