Nizol 200 Mg Tablet 10

Nizol 200 mg Tablet 10 is used to treat systemic fungal infections when other therapies have failed or are not tolerated.

Uses of Nizol 200 mg Tablet 10 are:

• Blastomycosis and Histoplasmosis: Treats these systemic fungal infections.
• Coccidioidomycosis: Treats this fungal infection affecting internal organs.
• Chromomycosis and Paracoccidioidomycosis: Treats these fungal infections when alternative antifungals cannot be used.

Here's how to take Nizol 200 Mg Tablet 10 :

• Swallow the tablet whole with a glass of water.

• Avoid crushing or chewing the tablet.

• Always take this medicine with food to minimise gastric irritation and enhance absorption.

• Do not exceed the prescribed dose without consulting your doctor.

• If you are taking acid-lowering medicines, ensure there is at least a 2-hour gap before or after taking this medicine.

Nizol 200 Mg Tablet 10 is taken orally.

Nizol 200 Mg Tablet 10 contains ketoconazole (200 mg) which has multiple mechanisms of action:

• Inhibition of Ergosterol Synthesis: Ketoconazole works by inhibiting an enzyme known as 14α-demethylase in fungi. This enzyme is responsible for the conversion of lanosterol into ergosterol - a vital component of fungal cell membranes.

• Disruption of Fungal Cell Membrane: By blocking ergosterol synthesis, ketoconazole disrupts the structure and function of the fungal cell membrane. This increased permeability allows leakage of cellular contents leading to cell death and halts fungal growth.

• Reduction in Human Hormone Synthesis: Ketoconazole may also reduce the synthesis of testosterone and cortisol in humans by inhibiting certain enzymes. These effects are usually reversible once you stop taking the medicine.

Store Nizol 200 Mg Tablet 10 in a tightly sealed container.

• Maintain a room temperature below 30°C.

• Keep the medicine out of direct sun light and avoid damp areas.

• Always keep it out of the reach of children.

• Make sure you use the medication before its expiry date.

• As Nizol 200 Mg Tablet 10 is used for managing systemic fungal infections, maintaining good personal hygiene can help manage the condition. Regularly wash your hands and avoid sharing personal items like towels or combs.

• Include probiotics in your diet. Foods like yoghurt can support a healthy gut microbiome, which can potentially help in controlling fungal growth. Always consult your doctor before making any significant dietary changes.