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CompositionNicomalom 2 Tablet 30 is used to prevent and treat dangerous blood clots in the body, placing it in the class of oral anticoagulants (blood thinners). This medicine is indicated for conditions like deep vein thrombosis (DVT) and pulmonary embolism (PE). It works to prevent harmful clot formation and is crucial for reducing the risk of stroke in patients with non-valvular atrial fibrillation, preventing repetitive heart attacks, and managing transient ischaemic attacks.
Nicomalom 2 Tablet 30 is prescribed for preventing and treating deep vein thrombosis (DVT) and pulmonary embolism. It also reduces the risk of stroke in patients with atrial fibrillation and prevents blood clots in individuals with artificial heart valves or at high risk of recurrent heart attacks. This tablet helps manage blood clotting disorders and prevent clots following surgery.
Follow these instructions while taking Nicomalom 2 Tablet 30:
Swallow the tablet whole with a full glass of water.
Do not crush, chew, or break the tablet.
Take this medicine at the same time each day to maintain consistent blood levels.
Take this medicine exactly as prescribed by your doctor.
Nicomalom 2 Tablet 30 is taken orally.
Nicomalom 2 Tablet 30 may cause bleeding from the nose or gums, unusual bruising, dizziness, nausea, diarrhoea, hair loss, purple toe syndrome, and skin necrosis.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Nicomalom 2 Tablet 30. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Nausea: Taking Nicomalom 2 Tablet 30 with food can help reduce feelings of sickness.
Dizziness: Consider taking this medicine at bedtime to minimise the impact of dizziness on your daily activities.
Nicomalom 2 Tablet 30 contains nicoumalone (2 mg), which works on the body as follows:
Vitamin K Antagonist: Nicoumalone acts by blocking the action of vitamin K, which is essential for the production of certain clotting factors in your liver.
Clotting Factor Inhibition: It specifically inhibits the production of clotting factors II, VII, IX, and X, which are proteins that play a crucial role in blood clot formation.
Prolonged Clotting Time: By reducing the levels of these important clotting proteins, nicoumalone effectively prolongs the time it takes for your blood to clot.
Preventive Action: While this medicine prevents new blood clots from forming, it does not directly dissolve clots that have already formed in your body.
Nicomalom 2 Tablet 30 is not recommended during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Be careful while taking Nicomalom 2 Tablet 30 if you are breastfeeding. It is best to talk with your doctor before taking this medicine.
You should limit or avoid alcohol while taking Nicomalom 2 Tablet 30. Alcohol can increase the risk of bleeding and may affect your liver function, which could change how this medicine works in your body.
Caution is advised while taking Nicomalom 2 Tablet 30 in case of mild to moderate liver impairment. If you have liver problems, discuss them with your doctor before starting this medicine.
Caution is advised before using Nicomalom 2 Tablet 30 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.
You may continue driving and using machines while on Nicomalom 2 Tablet 30 unless you experience side effects like dizziness or unusual bleeding. If you notice any symptoms, avoid these activities until you feel better.
If you have a known allergy to nicoumalone or any other ingredients in Nicomalom 2 Tablet 30, do not take this medicine. Tell your doctor about all your allergies before starting treatment.
Caution is advised while giving Nicomalom 2 Tablet 30 to children under 18 years of age. Always discuss with your doctor before giving any medicine to a child.
Older patients should take Nicomalom 2 Tablet 30 under medical supervision, as they may be more sensitive to its side effects. Your doctor will guide you based on your health status.
Nicomalom 2 Tablet 30 interacts with the following medicines:
Aspirin and NSAIDs: Medications like ibuprofen and diclofenac increase your bleeding risk when taken with Nicomalom 2 Tablet 30.
Antibiotics: Medicines like ciprofloxacin and erythromycin can enhance the blood-thinning effect of Nicomalom 2 Tablet 30, potentially causing excessive bleeding.
Antifungals: Medications such as fluconazole and ketoconazole can increase nicoumalone levels in your blood, requiring dose adjustments.
Antiepileptics: Medicines like carbamazepine and phenytoin can decrease the effectiveness of Nicomalom 2 Tablet 30, reducing its blood-thinning action.
Heart medicines: Amiodarone and other similar heart medicines can strengthen the effect of Nicomalom 2 Tablet 30.
Nicomalom 2 Tablet 30 interacts with the following foods:
Cranberry juice: May increase the blood-thinning effect, raising bleeding risk.
Nicomalom 2 Tablet 30 interacts with the following diseases:
Liver disease: The medicine may build up in your body as the liver cannot process it properly, increasing bleeding risk.
Kidney disease: May affect how your body handles Nicomalom 2 Tablet 30, requiring dose adjustments.
Uncontrolled high blood pressure: Increases your risk of bleeding complications when taking this medicine.
Recent or active bleeding conditions: The blood-thinning effect can worsen existing bleeding problems.
The daily dose of Nicomalom 2 Tablet 30 should be taken as prescribed by your doctor. The dosage may vary based on your blood test results and medical condition. Never change your dose without consulting your doctor. Regular monitoring of your blood clotting time is essential.
Taking too much Nicomalom 2 Tablet 30 may cause unusual bleeding or bruising. You might notice bleeding gums, nosebleeds, blood in urine, or dark stools. If you experience any of these symptoms, consult your doctor promptly.
If you forget to take Nicomalom 2 Tablet 30, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue your regular schedule. Never take a double dose to make up for a missed one.
Store Nicomalom 2 Tablet 30 at room temperature (not exceeding 30°C) in its original packaging.
Keep the medicine in a original container, protected from light and moisture.
Do not store in bathroom cabinets or other damp places.
Always keep this medicine out of sight and reach of children.
Check the expiry date before use and do not take after this date.
Maintain a consistent intake of vitamin K-rich foods (like green leafy vegetables) rather than suddenly changing your diet, as dramatic changes can affect how well your blood-thinning medicine works.
Limit alcohol consumption, as it can increase bleeding risk and affect liver function, which is important for processing nicoumalone.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Blood clots, Stroke prevention, Heart attack prevention |
| Drug Category | Vitamin K antagonist |
| Therapeutic Category | Anticoagulant |
Take it as soon as you remember. If it's almost time for your next dose, skip the missed one. Never double your dose to make up for a forgotten one.
Avoid aspirin and ibuprofen, as they increase bleeding risk. Always consult your doctor before taking any additional medicines.
This depends on your condition. Some people need it for a few months, while others require it long-term. Follow your doctor's guidance about treatment duration.
Maintain a consistent intake of vitamin K-rich foods like spinach and kale. Sudden changes can affect how well nicoumalone works in your body.
Look out for unusual bruising, nosebleeds, bleeding gums, blood in urine or stools, heavy periods, and prolonged bleeding from cuts. Report these to your doctor.
Yes, you'll need regular blood tests to check your INR test results. These tests help your doctor ensure the medicine is working properly.
Limit alcohol intake, as it may increase bleeding risk and affect how nicoumalone works. Consult your doctor about whether any amount is safe for you.
Check out Editorial Policy
Acenocoumarol: Uses, Interactions, Mechanism of Action https://go.drugbank.com/drugs/DB01418
National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 54676537, Acenocoumarol. Retrieved May 14, 2025 from https://pubchem.ncbi.nlm.nih.gov/compound/Acenocoumarol.
BRAFIELD A. J. (1959). Nicoumalone: a new anticoagulant. British medical journal, 1(5131), 1211–1213. https://doi.org/10.1136/bmj.1.5131.1211
Acenocoumarol (N.d.). Retrieved May 14, 2025, from https://www.sciencedirect.com/topics/neuroscience/acenocoumarol
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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