Migranex 10 Tablet 10 is used to prevent migraine headaches in adults by reducing the frequency and intensity of attacks, helping improve daily functioning and quality of life.
It contains flunarizine, a calcium channel blocker used for migraine prevention. It is intended for preventive use rather than relief during an ongoing migraine attack. Take it regularly as prescribed by your doctor.
Keeping a regular sleep schedule, staying hydrated, managing stress and identifying and avoiding your personal migraine triggers can support prevention alongside this medicine.
Tell your doctor if you have depression, Parkinson's disease or other movement problems before use. If you notice mood changes, unusual movements, marked drowsiness or visual disturbances, inform your doctor promptly. Continue treatment for the full prescribed duration and do not stop it suddenly without medical advice.
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Migranex 10 Tablet 10
Strip of 10 Units
MRP ₹51.45
₹44.76
₹5.15/Units
100% genuine medicines
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15 days Easy returns
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Store Below 30° C
CompositionAbout Migranex 10 Tablet 10
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Uses of Migranex 10 Tablet 10
Migranex 10 Tablet 10 is used in adults for the prevention of migraine attacks, reducing how often and how severely migraines occur.
Uses of Migranex 10 Tablet 10 are:
- Migraine Prevention: Reduces the frequency and intensity of migraine episodes.
- Quality of Life: Helps improve daily functioning by reducing the need for acute migraine treatments.
Directions for Use of Migranex 10 Tablet 10
Here are some instructions to follow while taking Migranex 10 Tablet 10:
- Swallow the tablet whole with a glass of water.
- Avoid crushing or chewing the tablet.
- Try to take it at the same time each day to maintain a consistent level of the medicine in your body.
- Stopping the use of this medicine suddenly is not advised. Always consult your doctor first.
Route of Administration
Migranex 10 Tablet 10 is taken orally.
Side Effects of Migranex 10 Tablet 10
Migranex 10 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Migranex 10 Tablet 10 are:
- Neurological: Drowsiness and mood changes.
- Metabolic: Weight gain.
- Digestive: Dry mouth, stomach discomfort and feeling sick (nausea).
- Musculoskeletal: Muscle aches.
- Sleep and Skin: Difficulty sleeping (insomnia) and skin rash.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary, usually harmless, and resolve upon stopping the use of Migranex 10 Tablet 10. However, if you experience serious side effects or worsening of symptoms, consult your doctor.
Here are some general guidelines for managing common side effects:
- Drowsiness: If this medicine makes you feel sleepy, you may want to take it at bedtime.
- Nausea: If you experience stomach discomfort, taking Migranex 10 Tablet 10 with meals could lessen this effect.
How Migranex 10 Tablet 10 Works?
Migranex 10 Tablet 10 contains flunarizine (10 mg), which works on your body in the following ways:
- Selective calcium channel blocking: Flunarizine acts as a selective calcium entry blocker, preventing the flow of calcium into arterial smooth muscle cells in your brain. This action plays a pivotal role in preventing migraines.
- Vasodilation inhibition: The medicine also inhibits both arterial vasoconstriction and vasodilation involved in the development of migraines. It helps prevent abnormal tightening and widening of blood vessels in your brain, which is believed to trigger migraines.
- Antihistaminic effects: Additionally, flunarizine also has mild antihistaminic effects that could potentially contribute to its effectiveness against migraines.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Migranex 10 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.
Breastfeeding
If you are breastfeeding, exercise caution before taking Migranex 10 Tablet 10. Consult your doctor to understand the potential risks and benefits.
Alcohol
Alcohol should be avoided while taking this medicine, as it can exacerbate drowsiness, a common side effect of Migranex 10 Tablet 10.
Liver
If you have a history of liver problems, discuss them with your doctor before starting Migranex 10 Tablet 10. This medicine may affect liver function.
Kidney
Consult your doctor before using Migranex 10 Tablet 10 if you have any previous kidney health issues.
Use In Driving And Operating Machinery
Migranex 10 Tablet 10 may cause drowsiness, affecting your ability to drive or operate machinery. See how this medicine affects you before engaging in these activities.
Allergy
Avoid this tablet if you are allergic to flunarizine. Before starting Migranex 10 Tablet 10, disclose all your known allergies to your doctor.
Children
Caution is advised while giving Migranex 10 Tablet 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Migranex 10 Tablet 10 under medical supervision, as they may be more prone to its side effects. Caution is advised if patients are over 70 years of age.
Interactions of Migranex 10 Tablet 10
Drug-Drug Interactions
Migranex 10 Tablet 10 interacts with the following medicines:
- CNS depressants: The sedative effects of these medicines can be enhanced when taken with Migranex 10 Tablet 10. These include benzodiazepines like diazepam and alprazolam, barbiturates like phenobarbital and butalbital, antipsychotics like haloperidol and risperidone, and opioids like morphine and codeine.
- Anti-seizure medicines: Medicines like carbamazepine, phenytoin, or valproate may have their drowsiness-inducing effects heightened when combined with Migranex 10 Tablet 10.
- Antihistamines: Medications such as diphenhydramine or cetirizine can increase drowsiness if taken along with this tablet.
- Antidepressants: SSRIs and SNRIs, for example, fluoxetine and venlafaxine, respectively, can increase the risk of serotonin syndrome, a serious condition, when taken with Migranex 10 Tablet 10.
Drug-Food Interactions
There are no significant interactions between Migranex 10 Tablet 10 and food.
Drug-Disease Interactions
Migranex 10 Tablet 10 interacts with the following diseases:
- Depression: If you have a history of depression, you should use Migranex 10 Tablet 10 cautiously since it may exacerbate your symptoms.
- Liver disease: If you have a liver condition, the ability to metabolise Migranex 10 Tablet 10 may be impaired, leading to increased blood levels of the medicine.
- Heart conditions: Individuals with heart problems such as sick sinus syndrome or heart block should take this medicine cautiously since it can affect heart function.
Dosage of Migranex 10 Tablet 10
Daily Dose
Your doctor will prescribe the recommended dose of Migranex 10 Tablet 10 for you based on your health condition and your response to the medication. It's crucial not to exceed this dosage unless your doctor advises you to do so.
Over Dose
If you happen to take more than your prescribed dose of Migranex 10 Tablet 10, you may experience symptoms such as excessive drowsiness and low blood pressure. If this occurs, inform your doctor immediately.
Missed Dose
If you forget to take your regular dose of Migranex 10 Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.
Storage
- Store Migranex 10 Tablet 10 at room temperature in a cool, dry place.
- Keep it in a tightly sealed container, protected from light and moisture.
- Ensure the medicine is kept out of reach of children.
- Use this medication before its expiration date.
Special Dietary And Lifestyle Recommendation
- Given that Migranex 10 Tablet 10 is taken for managing migraines, try to avoid food triggers that could prompt migraines. This can include items such as aged cheese, caffeine, and alcoholic beverages.
- Regular physical exercise may help reduce the frequency of migraine attacks. Choose a low-impact activity, like walking or swimming, to decrease your chances of triggering a migraine.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Migraine Prevention |
| Drug Category | Calcium Channel Blocker |
| Therapeutic Category | Antimigraine |
Frequently Asked Questions (FAQs)
What is Migranex 10 Tablet 10 used for?
Migranex 10 Tablet 10 is used to prevent migraine headaches. It helps reduce the frequency and severity of attacks, improving daily functioning.
How does Migranex 10 Tablet 10 work?
Migranex 10 Tablet 10 contains flunarizine, a calcium channel blocker. It improves blood flow in the brain by preventing the abnormal dilation of blood vessels linked to migraines.
Can I take Migranex 10 Tablet 10 with my other medicines?
Some medicines may interact with flunarizine, enhancing their sedative effects. Always consult your doctor before starting new medications.
Will Migranex 10 Tablet 10 make me drowsy?
Yes, drowsiness is a common side effect of flunarizine. This may affect your ability to drive or operate machinery, so caution is advised.
How long does it take for Migranex 10 Tablet 10 to work?
Migranex 10 Tablet 10 may take 6-8 weeks to show noticeable effects in preventing migraines. Full benefits are usually seen after 3 months of treatment.
Will I gain weight due to Migranex 10 Tablet 10?
Yes, weight gain is a common side effect due to increased appetite. Following a balanced diet and regular exercise can help manage weight.
Can I take Migranex 10 Tablet 10 during pregnancy?
Exercise caution before taking Migranex 10 Tablet 10 if you are pregnant, and consult your doctor first.
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Manufacturer details
Country of origin: INDIA
References
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 941361, Flunarizine. https://pubchem.ncbi.nlm.nih.gov/compound/Flunarizine
- Great Ormond Street Hospital for Children. (2016, Apr). Flunarizine to prevent migraine. NHS Foundation Trust. https://www.gosh.nhs.uk/conditions-and-treatments/medicines-information/flunarizine-prevent-migraine/
- DrugBank Online. (2024, Jun 9). Flunarizine. https://go.drugbank.com/drugs/DB04841
- Holmes, B., Brogden, R. N., Heel, R. C., Speight, T. M., & Avery, G. S. (1984). Flunarizine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use. Drugs, 27(1), 6–44. https://doi.org/10.2165/00003495-198427010-00002
- Sorge, F., De Simone, R., Marano, E., Nolano, M., Orefice, G., & Carrieri, P. (1988). Flunarizine in prophylaxis of childhood migraine. A double-blind, placebo-controlled, crossover study. Cephalalgia: an international journal of headache, 8(1), 1–6. https://doi.org/10.1046/j.1468-2982.1988.0801001.x
- Leone, M., Grazzi, L., La Mantia, L., & Bussone, G. (1991). Flunarizine in migraine: a minireview. Headache, 31(6), 388–391. https://doi.org/10.1111/j.1526-4610.1991.hed3106388.x
- Thomas, M., Behari, M., & Ahuja, G. K. (1991). Flunarizine in migraine prophylaxis: an Indian trial. Headache, 31(9), 613–615. https://doi.org/10.1111/j.1526-4610.1991.hed3109613.x
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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