Met Xl 3d 25/12.5 Tablet 15

Ajanta Pharma Ltd

Strip of 15 Units

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MRP ~~₹245~~

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Composition

Chlorthalidone (12.5 Mg) + Metoprolol Succinate (25 Mg) + Telmisartan (40 Mg)

Met Xl 3d 25/12.5 Tablet 15 is used to manage essential hypertension (high blood pressure) and stable coronary artery disease. It is a combination medicine that belongs to the antihypertensive medication class.

In addition to managing high blood pressure, this medicine helps reduce the workload on your heart. It also helps prevent complications such as stroke or heart attack in people with coronary artery disease, which is characterised by blockage in the heart's blood vessels that causes chest pain during physical activity.

You should take this medicine orally as advised by your doctor. The dosage depends on factors such as your age, body weight, and the severity of your condition. It is important to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while taking this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for best results.

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Met Xl 3d 25/12.5 Tablet 15 is used for the following:

Controlling high blood pressure
Treating stable coronary artery disease
Preventing chest pain during physical activity
Reducing the risk of cardiovascular complications
Lowering the workload on the heart
Helping regulate irregular heartbeat
Preventing morning headaches related to high blood pressure
Managing blood pressure in adults with heart conditions

Follow these instructions while taking Met Xl 3d 25/12.5 Tablet 15:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or break the extended-release tablet.
Take this medicine at the same time each day for best results.
Do not suddenly stop taking this medicine without consulting your doctor.

Met Xl 3d 25/12.5 Tablet 15 is taken orally.

Met Xl 3d 25/12.5 Tablet 15 may have the following common side effects:

Dizziness
Headache
Nausea
Fatigue
Low blood pressure: This occurs when your blood pressure drops below normal levels, making you feel lightheaded when standing up quickly.
Constipation

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Met Xl 3d 25/12.5 Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some ways to manage common side effects:

Nausea: Taking this medicine with food may help reduce stomach upset.
Dizziness: Consider taking Met Xl 3d 25/12.5 Tablet 15 in the morning rather than evening to minimise dizziness during the day.

Met Xl 3d 25/12.5 Tablet 15 contains three active ingredients that work together to lower blood pressure and reduce heart workload:

Telmisartan (40 mg): This component blocks the effects of angiotensin II, a hormone that causes blood vessels to narrow, allowing your blood vessels to relax and widen, which reduces blood pressure.
Chlorthalidone (12.5 mg): This diuretic enhances sodium and water excretion from the body, helping to reduce blood volume and thereby lowering blood pressure.
Metoprolol Succinate (25 mg): This beta-blocker works by blocking the effects of stress hormones on the heart by targeting beta-1 receptors. This helps to slow the heart rate and reduce the force of heart contractions.

Pregnancy

Be careful while taking Met Xl 3d 25/12.5 Tablet 15 if you are pregnant. It is ideal to discuss with your doctor before taking this medicine.

Breastfeeding

Take care while taking Met Xl 3d 25/12.5 Tablet 15 if you are breastfeeding. It is best to talk with your doctor before taking this medicine.

Alcohol

Care is advised when consuming alcohol while taking Met Xl 3d 25/12.5 Tablet 15. Alcohol may increase the risk of experiencing low blood pressure, dizziness, and fatigue when combined with this medicine.

Liver

Be careful while taking Met Xl 3d 25/12.5 Tablet 15 if you have liver problems. This medicine contains components that are processed by your liver. Before starting this medicine, inform your doctor about any existing liver conditions.

Kidney

Caution is advised before using Met Xl 3d 25/12.5 Tablet 15 if you have a history of any kidney problems. This medicine contains chlorthalidone, which affects kidney function. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Take care when driving or operating machinery while using Met Xl 3d 25/12.5 Tablet 15. This medicine may cause dizziness or fatigue in some people, which could affect your ability to concentrate and react quickly.

Allergy

If you have any known allergies to chlorthalidone, metoprolol, telmisartan, or any other medicines, inform your doctor before taking Met Xl 3d 25/12.5 Tablet 15. Allergic reactions may include skin rash, itching, or swelling.

Children

Caution is advised while giving Met Xl 3d 25/12.5 Tablet 15 to children under 18. Always talk with your doctor before giving any medicine to a child.

Older Patients

Older patients should take Met Xl 3d 25/12.5 Tablet 15 under medical supervision, as they may be more sensitive to its effects. Dosage adjustments might be necessary for patients over 65. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Met Xl 3d 25/12.5 Tablet 15 interacts with the following medicines:

Anti-diabetic medicines: Medicines like metformin, glimepiride and insulin may have reduced effectiveness when taken with Met Xl 3d 25/12.5 Tablet 15, requiring close monitoring of blood glucose levels.
Non-steroidal anti-inflammatory drugs (NSAIDs): Medicines such as ibuprofen or diclofenac may reduce the blood pressure-lowering effects of Met Xl 3d 25/12.5 Tablet 15.
Digoxin: When taken alongside Met Xl 3d 25/12.5 Tablet 15, digoxin levels may increase in the blood, potentially leading to increased side effects.
Lithium: Met Xl 3d 25/12.5 Tablet 15 may increase lithium levels in the blood, causing lithium toxicity.

Drug-Food Interactions

Met Xl 3d 25/12.5 Tablet 15 interacts with the following foods:

Grapefruit or grapefruit juice: Grapefruit or grapefruit juice should be avoided when taking Met Xl 3d 25/12.5 Tablet 15 as it may intensify the medicine's effects, potentially causing unwanted side effects.

Drug-Disease Interactions

Met Xl 3d 25/12.5 Tablet 15 interacts with the following diseases:

Kidney problems: May worsen kidney function in patients with existing kidney issues.
Liver disease: People with liver problems may experience increased sensitivity to this medicine.
Diabetes: May affect blood sugar control, requiring careful monitoring of glucose levels.
Coronary artery disease: Sudden withdrawal of this medicine might worsen chest pain or trigger a heart attack.

Daily Dose

The daily dose of Met Xl 3d 25/12.5 Tablet 15 should be taken as prescribed by your doctor. Your dosage may vary based on your condition's severity, age, weight, and how your body responds to the medicine. Never change your dosage without consulting your doctor.

Over Dose

Taking more than the prescribed dosage of Met Xl 3d 25/12.5 Tablet 15 may cause dizziness, extreme tiredness, low blood pressure, nausea, headache, and increased urination. If you experience fainting or severe weakness, contact your doctor for advice about what to do next.

Missed Dose

If you forget to take your Met Xl 3d 25/12.5 Tablet 15, take it when you remember. However, if it's nearly time for your next scheduled dose, skip the missed one and continue with your regular schedule. Never take a double dose to make up.

Store Met Xl 3d 25/12.5 Tablet 15 at room temperature (below 30°C).
Keep away from direct sunlight, heat, and moisture.
Store in the original packaging until ready to use.
Keep out of reach of children and pets.
Do not use the medicine after the expiry date printed on the package.

Reduce your sodium intake by avoiding processed foods, canned soups, and table salt. High sodium consumption can worsen high blood pressure.
Engage in regular moderate physical activity, such as brisk walking, for 30 minutes daily to improve heart health and help manage your blood pressure levels.

Fact Box

Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Hypertension, Coronary artery disease
Drug Category	Multi-action antihypertensive
Therapeutic Category	Antihypertensive combination

What is the use of Met Xl 3d 25/12.5 Tablet 15?

Met Xl 3d 25/12.5 Tablet 15 is used to manage high blood pressure and stable heart conditions where the heart's blood vessels are narrowed.

How does Met Xl 3d 25/12.5 Tablet 15 work?

It combines three medicines that work together: a water pill, a medicine that relaxes blood vessels, and another that reduces heart workload.

Can I take Met Xl 3d 25/12.5 Tablet 15 at any time of day?

It's best taken during daytime or at least four hours before bedtime to avoid night-time trips to the toilet.

What side effects might I experience with this medicine?

Common side effects include dizziness, headache, tiredness, upset stomach, and sometimes low blood pressure when standing up quickly.

Is it safe to use Met Xl 3d 25/12.5 Tablet 15 during pregnancy?

No, pregnant women should consult their doctor before using this medicine as it may harm the developing baby.

Can I stop taking Met Xl 3d 25/12.5 Tablet 15 once my blood pressure is normal?

No, sudden stopping can cause your blood pressure to rise dangerously. Only change your medicine schedule with your doctor's guidance.

Do I need regular check-ups while taking this medicine?

Yes, your doctor will want to check your kidney function, salt levels in your blood, and blood pressure regularly.

Last Updated On 23 May. 2025 | 10:20AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

54, Sir Mathuradas Vasanji Rd, Hanuman Nagar, Andheri East, Mumbai, Maharashtra 400053

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

AstraZeneca AB. (2010). HIGHLIGHTS OF PRESCRIBING INFORMATION. Metoprolol succinate. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/019962s041lbl.pdf
Boehringer Ingelheim Limited. (2017, November). Telmisartan. Bracknell, Berkshire. https://www.boehringer-ingelheim.com/human-health/products/micardis
Sarkar, G., Gaikwad, V. B., Sharma, A., Halder, S. K., Kumar, D. A., Anand, J., Agrawal, S., Kumbhar, A., Kinholkar, B., Mathur, R., Doshi, M., Bachani, D., & Mehta, S. (2021). Fixed-dose combination of Metoprolol, Telmisartan, and Chlorthalidone for essential hypertension in adults with stable coronary artery disease: Phase III study. Advances in Therapy, 39(2), 923-942. https://doi.org/10.1007/s12325-021-01971-9
Chlorthalidone: MedlinePlus drug information. (2017, June 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682342.html

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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