Isryl M 1 Tablet Pr 15

Systopic Laboratories Private Limited

Strip of 15 Units

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Old MRP ₹45

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Composition

Glimepiride (1 Mg) + Metformin (500 Mg)

Isryl M 1 Tablet Pr 15 is used to manage type 2 diabetes mellitus. It helps control blood sugar levels by increasing insulin release and improving how the body uses it. This tablet reduces the risk of complications such as blindness, kidney damage, heart problems, and nerve issues, while supporting a healthier lifestyle in people with uncontrolled blood sugar.

This medicine should be taken orally as directed by your doctor. Inform your doctor if you have any pre-existing conditions or are on any other medications before starting this medication. If you notice any side effects while using this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor to achieve optimal results.

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Isryl M 1 Tablet Pr 15 is used to treat type 2 diabetes. It helps control high blood sugar levels by improving how the body uses insulin and reducing sugar production in the liver, lowering the risk of diabetes-related complications.

Swallow the tablet as prescribed by your doctor, preferably with a meal or as instructed.
Avoid crushing or chewing the tablet.
Never take more than your doctor has recommended.
It's crucial not to stop taking this medicine without first consulting your doctor.

Isryl M 1 Tablet Pr 15 is taken orally.

Isryl M 1 Tablet Pr 15 may have the following common side effects:

Hypoglycaemia
Nausea
Vomiting
Diarrhoea
Abdominal pain
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Isryl M 1 Tablet Pr 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hypoglycaemia: If you experience low blood sugar after taking Isryl M 1 Tablet Pr 15, consider having a small meal or snack to help manage this side effect.
Nausea or Vomiting: Taking Isryl M 1 Tablet Pr 15 with food may reduce feelings of nausea or prevent vomiting.

Isryl M 1 Tablet Pr 15 contains two active ingredients that work together to help manage blood sugar levels:

Glimepiride (1 mg): This component of Isryl M 1 Tablet Pr 15 belongs to the sulfonylurea class of medications. It works by stimulating the pancreas – specifically an area called beta cells – to produce more insulin, which helps regulate blood sugar levels.
Metformin (500 mg): As a biguanide, metformin has several functions in managing blood sugar levels. It reduces the amount of glucose the liver produces and improves how effectively your body uses insulin. Additionally, it increases glucose uptake in your body's cells, which helps lower overall blood sugar levels.

Pregnancy

Caution is advised while taking Isryl M 1 Tablet Pr 15 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, please discuss with your doctor before starting Isryl M 1 Tablet Pr 15.

Alcohol

Avoid excessive alcohol intake while on Isryl M 1 Tablet Pr 15 as it increases the risk of lactic acidosis with metformin.

Liver

This medicine should be used with caution if you have liver problems. Make sure to discuss any liver-related issues with your doctor before starting this medication.

Kidney

Caution is advised when using this tablet if you have a history of kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

As Isryl M 1 Tablet Pr 15 can cause side effects like dizziness or tiredness, caution is advised while driving or operating machinery until you know how the medicine affects you.

Allergy

Isryl M 1 Tablet Pr 15 is warned against use in patients with a known hypersensitivity to glimepiride, metformin, or any other component of the formulation.

Children

Isryl M 1 Tablet Pr 15 is not recommended for use in children as it's intended for adult use only.

Older Patients

Older patients should take Isryl M 1 Tablet Pr 15 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Isryl M 1 Tablet Pr 15 can interact with the following medicines:

Anti-diabetic medications such as insulin or gliclazide may enhance the blood sugar-lowering effect of Isryl M 1 Tablet Pr 15, increasing the risk of hypoglycaemia.
ACE inhibitors and Angiotensin II receptor antagonists: Medicines like enalapril or losartan can potentiate the hypoglycaemic effect of this medication.
Thiazides and Corticosteroids like hydrochlorothiazide or prednisolone may reduce the blood sugar-lowering effect of the medicine.
Oral contraceptives and Estrogen, such as ethinyl estradiol and levonorgestrel, can decrease the hypoglycaemic effect of Isryl M 1 Tablet Pr 15.
H2 blockers such as cimetidine can increase metformin levels in your body, enhancing its action.
Carbonic anhydrase inhibitors like acetazolamide can increase the risk of lactic acidosis when used with metformin in Isryl M 1 Tablet Pr 15.

Drug-Food Interactions

Certain foods may interact with Isryl M 1 Tablet Pr 15:

High-Fat diet: This can decrease the absorption of metformin, reducing its effectiveness.

Drug-Disease Interactions

Isryl M 1 Tablet Pr 15 can interact with the following diseases:

Kidney disease: If you have kidney problems, this tablet can accumulate in your body, posing a risk for lactic acidosis.
Liver disease: As the liver clears metformin, liver diseases might alter metformin levels in your body.
Heart disease: Caution is needed if you have heart disease as lactic acidosis, though rare, can occur due to metformin in Isryl M 1 Tablet Pr 15.
Glucose 6-phosphate dehydrogenase (G6PD) deficiency: If you have G6PD deficiency, Isryl M 1 Tablet Pr 15 may cause haemolytic anaemia.

Daily Dose

The daily dose of Isryl M 1 Tablet Pr 15 should be taken as advised by your doctor. The dosage may differ depending on the severity of your condition and how you respond to the medication. It's crucial not to exceed the prescribed dosage without a doctor's consultation.

Over Dose

An overdose of Isryl M 1 Tablet Pr 15 might lead to nausea, diarrhoea, abdominal discomfort, and headaches. If you experience these symptoms after taking more than your prescribed dose, inform your doctor.

Missed Dose

If you miss a dose of Isryl M 1 Tablet Pr 15, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not increase your dose without consulting your doctor.

Keep Isryl M 1 Tablet Pr 15 at room temperature below 30°C.
Protect the product from both light and moisture to maintain its efficacy.
Ensure that you store this medicine out of reach of children for safety.
Always check the expiry date before use.

Maintain a diet low in refined sugars. Opt for complex carbohydrates with a lower glycaemic index to help regulate your blood sugar levels.
Incorporate regular physical activity into your lifestyle. Even moderate exercise like walking can improve your body's sensitivity to insulin, aiding in managing your blood sugar levels.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Anti-hyperglycaemic Agents
Therapeutic Category	Antidiabetic

What is Isryl M 1 Tablet Pr 15 used for?

Isryl M 1 Tablet Pr 15 is used to treat type 2 diabetes in adults. It helps lower blood sugar levels when used with a healthy diet and exercise by making the body use insulin better.

How does Isryl M 1 Tablet Pr 15 Work?

This medicine works by increasing insulin production from the pancreas and enhancing your body's sensitivity to insulin, thereby reducing blood sugar levels.

How should I take Isryl M 1 Tablet Pr 15?

You should take Isryl M 1 Tablet Pr 15 orally as prescribed by your doctor. Always swallow the whole tablet without crushing or chewing them. Your doctor will instruct you about the dosage and frequency of medication.

What precautions should I take while using Isryl M 1 Tablet Pr 15?

Avoid excessive alcohol intake while using this medicine, and inform your doctor if you experience persistent symptoms of high or low blood sugar.

Can I take other medicines while using Isryl M 1 Tablet Pr 15?

Certain medicines, such as enalapril or losartan and hydrochlorothiazide or prednisolone, can affect the efficacy of Isryl M 1 Tablet Pr 15. Always consult your doctor about all medications and supplements you are taking before starting this medicine.

What are the side effects of using Isryl M 1 Tablet Pr 15?

Common side effects include low blood sugar, nausea, vomiting, diarrhoea, abdominal pain, and headaches. Consult your doctor if these persist or worsen.

How should I store my Isryl M 1 Tablet Pr 15?

Store your tablets at room temperature below 30°C, protected from light and moisture. Keep them out of reach of children.

Last Updated On 15 Sep. 2025 | 11:43AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

101 PRAGATI CHAMBERS RANJIT NAGAR COMMERCIAL , NEW DELHI, Delhi, India - 110008

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

NHS UK. (n.d.). How and when to take glimepiride. Retrieved from https://www.nhs.uk/medicines/glimepiride/how-and-when-to-take-glimepiride/
DailyMed. (n.d.). Glimepiride tablet. Retrieved from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
U.S. Food and Drug Administration. (2015). Drug approval package: Synjardy (empagliflozin and metformin hydrochloride) tablets. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206073s003lbl.pdf
U.S. Food and Drug Administration. (n.d.). Metformin-containing drugs: Drug safety communication - revised warnings for certain patients with reduced kidney function. Retrieved from https://www.fda.gov/downloads/drugs/drugsafety/ucm280360.pdf
Metformin: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.-c). DrugBank. https://go.drugbank.com/drugs/DB00331
Glimepiride: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.-f). DrugBank. https://go.drugbank.com/drugs/DB00222

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

Telephone:09240250346

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