Glyciphage Sr 1gm Tablet 10

Franco Indian Pharmaceuticals Pvt Ltd

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MRP ~~₹45.2~~

₹36.16

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Composition

Metformin (1000 Mg)

Strength:

500 MG 850 MG 1000 MG

Glyciphage SR 1gm Tablet is predominantly used to manage type 2 diabetes mellitus. This medicine is part of a group of medications known as antidiabetic medications, specifically biguanides.

In addition to managing high blood sugar levels in type 2 diabetes, this medicine is also beneficial for adults who have not been able to achieve adequate glycemic control through diet and exercise alone. The sustained-release formulation of this tablet provides an added advantage, reducing the frequency of administration and making it a more convenient choice for patients.

Before you start taking this medicine, it's crucial to inform your doctor about any ongoing medications or existing medical conditions. Should you encounter any side effects throughout your course of medication, let your doctor know immediately. To reap the optimal benefits, it's important to continue taking the medicine for the full duration prescribed by your doctor.

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Glyciphage SR 1gm Tablet is used for the following:

Management of type 2 diabetes mellitus in adults
Enhancing insulin sensitivity in peripheral tissues
Decreasing glucose production in the liver
Reducing glucose absorption from the intestines

To take Glyciphage SR 1gm Tablet properly, follow these instructions:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or break the tablet.
Consult your doctor before making any changes to how and when to take this medicine.

Glyciphage SR 1gm Tablet is taken orally.

Glyciphage SR 1gm Tablet may cause the following side effects:

Diarrhoea
Nausea
Vomiting
Abdominal discomfort
Metallic taste: This is a peculiar taste that you might experience in your mouth.
Vitamin B12 deficiency: This can lead to low levels of vitamin B12 in your body, which can cause fatigue, weakness, and other symptoms.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Glyciphage SR 1gm Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Glyciphage SR 1gm Tablet with food.
Nausea: Consider taking this medicine with your evening meal to lessen this effect.

Glyciphage SR 1gm Tablet contains metformin (1000 mg), which acts on your body in several ways:

Reduces Intestinal Glucose Absorption: Metformin decreases the amount of glucose absorbed from the intestines into the bloodstream after eating.
Decreases Hepatic Gluconeogenesis: It also reduces the amount of glucose your liver produces, a process known as hepatic gluconeogenesis.
Enhances Peripheral Tissue Insulin Sensitivity: Metformin enhances the sensitivity of peripheral tissues to insulin, which improves the uptake and use of glucose in these tissues. This process helps to lower blood sugar levels without stimulating insulin secretion, which minimises the risk of hypoglycaemia when metformin is used on its own.

Pregnancy

Caution is advised while taking Glyciphage SR 1gm Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you're breastfeeding, make sure to discuss with your doctor before starting Glyciphage SR 1gm Tablet.

Alcohol

Alcohol consumption can increase the risk of lactic acidosis while taking Glyciphage SR 1gm Tablet. It's advisable to limit or avoid alcohol.

Liver

If you have liver health issues, it's recommended to discuss them with your doctor before starting Glyciphage SR 1gm Tablet. Your doctor will evaluate if this medicine is suitable for you.

Kidney

Caution is advised before using Glyciphage SR 1gm Tablet if you have a history of kidney problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

There's no known impact of Glyciphage SR 1gm Tablet on your ability to drive or operate machinery. However, each individual may respond differently to the medication.

Allergy

If you're allergic to metformin or any other components of Glyciphage SR 1gm Tablet, do not take this medicine. Consult your doctor for alternatives.

Children

Glyciphage SR 1gm Tablet is meant for adult use. Always consult your doctor before giving any medicine to children under 18 years of age.

Older Patients

Older patients should take Glyciphage SR 1gm Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Glyciphage SR 1gm Tablet interacts with the following medicines:

Cationic Medicines: Medicines like amiloride, digoxin, and ranitidine, which are removed from the body through renal tubular secretion, may cause an increase in metformin accumulation. This can potentially increase your risk of lactic acidosis.
Insulin Secretagogues: When used with medicines like glimepiride or glipizide (insulin secretagogues), Glyciphage SR 1gm Tablet may increase your risk of having low blood sugar or hypoglycemia.
Alcohol-containing Medications: Alcohol-containing medications, when taken alongside Glyciphage SR 1gm Tablet, could amplify your risk of developing lactic acidosis.

Drug-Food Interactions

Certain foods and beverages may interact with Glyciphage SR 1gm Tablet:

High-sugar Foods: Consuming high-sugar foods or drinks while taking this medicine may hinder your glycemic control.

Drug-Disease Interactions

Glyciphage SR 1gm Tablet interacts with the following diseases:

Renal Impairment: If you have kidney problems, you should use Glyciphage SR 1gm Tablet with caution, as this medicine is primarily eliminated via the kidneys.
Metabolic Acidosis: People suffering from metabolic imbalances such as diabetic ketoacidosis should avoid using this medicine as it can further exacerbate their condition.
Acute Conditions: Conditions that can affect kidney function, like dehydration or severe infection, may interact negatively with Glyciphage SR 1gm Tablet.

Daily Dose

The daily dose of Glyciphage SR 1gm Tablet should be taken as instructed by your doctor. The dosage might vary based on individual factors such as condition severity and response to the medication. It's essential to adhere to your doctor's prescribed dosage and not exceed it without their advice.

Over Dose

If you accidentally take more than the prescribed dose of Glyciphage SR 1gm Tablet, you might experience common side effects such as nausea, vomiting, diarrhoea, or abdominal discomfort. If these symptoms persist or worsen, it's important to inform your doctor.

Missed Dose

If you've missed a dose of Glyciphage SR 1gm Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. You should never increase your dosage without consulting your doctor.

Always keep the Glyciphage SR 1gm Tablet in its original packaging.
Store it at room temperature, ideally between 15 and 30°C.
Protect it from light and moisture.
Ensure it is out of reach of children.
Remember to take note of the expiry date and use the medicine before then.

Regular physical exercise: Engaging in regular physical activity like walking, jogging, or yoga will help manage your blood glucose levels effectively, complementing the action of the Glyciphage SR 1gm Tablet.
Balanced diet: Include plenty of fruits, vegetables, whole grains and lean proteins in your diet. Avoid processed foods and those high in sugar as these can disrupt your blood glucose levels. This dietary pattern will optimise the effects of Glyciphage SR 1gm Tablet.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Biguanide Antidiabetic
Therapeutic Category	Oral Antidiabetic

What is the Glyciphage SR 1gm Tablet used for?

Glyciphage SR 1gm Tablet is used to manage type 2 diabetes in adults, particularly when diet and exercise alone don't maintain adequate blood sugar control.

How does Glyciphage SR 1gm Tablet work?

The active ingredient, metformin, reduces glucose absorption from the intestines, decreases glucose production by the liver, and enhances insulin sensitivity in peripheral tissues.

Can I crush or chew the Glyciphage SR 1gm Tablet?

No, you should swallow the tablet whole without crushing, chewing or breaking it to maintain its sustained release properties.

What are some common side effects of Glyciphage SR 1gm Tablet?

Common side effects include gastrointestinal disturbances like nausea, vomiting, diarrhoea, abdominal discomfort and a metallic taste.

Can I take Glyciphage SR 1gm Tablet if I have renal impairment?

Patients with renal impairment should use this medicine with caution. Consult your doctor before initiating treatment.

Are there any medications that can interact with Glyciphage SR 1gm Tablet?

Yes, certain medications may interact with this medicine including cationic medicines and alcohol-containing medications. Always inform your doctor about any medicines you are taking.

How should I store my Glyciphage SR 1gm Tablets?

Store your tablets at room temperature (15-30°C) in a tightly closed container and keep them out of reach of children and pets.

Last Updated On 13 May. 2025 | 11:06AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

20, Dr. E. Moses Road, Mahalaxmi, Mumbai, Maharashtra 400011

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). METFORMIN HYDROCHLORIDE- metformin hydrochloride tablet, film coated. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=1200ea71-8a9e-4e49-bb77-7d9fe0d84ae7
U.S. Food and Drug Administration. (2006). Drug Approval Package: Fortamet (Metformin Hcl) NDA #021748. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 4091, Metformin. Retrieved November 17, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Metformin
Guarino, E., Nigi, L., Patti, A., Fondelli, C., & Dotta, F. (2012). Combination therapy with metformin plus vildagliptin in type 2 diabetes mellitus. Expert opinion on pharmacotherapy, 13(9), 1377–1384. https://doi.org/10.1517/14656566.2012.667078
LaMoia, T. E., & Shulman, G. I. (2021). Cellular and Molecular Mechanisms of Metformin Action. Endocrine reviews, 42(1), 77–96. https://doi.org/10.1210/endrev/bnaa023

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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